Showing 151–175 of 200 documents
Sorted by hybrid relevance (keyword + semantic via RRF)
Bibie Said, Yuan Pétermann, Patrick Howlett, Monia Guidi, Yann Thoma, et al.
…HIV) infection, diabetes mellitus (DM), and malnutrition in tuberculosis (TB) patients can alter drug concentrations, thereby affecting the treatment outcomes. For these populations, personalised strategies such as therapeutic drug monitoring (TDM) may be essential. We investigat…
Xiaoyi Zhang, Hai Zheng, Peng Zhou, Wenfeng Hu, Yuxin Si, et al.
…tors of systemic lupus erythematosus (SLE) complicated with tuberculosis (TB) infection through a systematic review and meta-analysis. **METHODS:** PubMed, Embase, Cochrane Library, and Web of Science databases were searched for relevant research articles on systemic lupus eryth…
Aishwarya Lakshmi Vidyasagaran, Noemia Teixeira de Siqueira Filha, Sampurna Kakchapati, Thomas Falconer Hall, Baby Naznin, et al.
… evaluate the impact of public-private mix (PPM) models for tuberculosis (TB) on health, process and system outcomes, adopting the WHO's definition of PPM, which is a strategic partnership between national TB programmes and healthcare providers, both public and private, to delive…
Sabbir Hossen Sabuz, Israt Jahan, Bristi Kona Debnath, Md Mominul Islam, Md Sadequl Islam
**BACKGROUND:** Tuberculosis (TB) remains a global health concern, with unpasteurized milk serving as a major source of zoonotic Mycobacterium bovis transmission in endemic, low-resource regions. **OBJECTIVE:** This meta-analysis investigates the prevalence of human TB cases lin…
Kayla Appel, Faeez Nackerdien, Carmen S Christian
**BACKGROUND:**  Tuberculosis (TB) remains a major public health issue in South Africa, a high-burden TB country. The coronavirus disease 2019 (COVID-19) pandemic has exacerbated challenges in accessing essential TB services. This scoping review explores how access to TB car…
Omri A Arbiv, Thomas Holmes, Marie JeongMin Kim, Marie Yan, Kamila Romanowski, et al.
…n (SDR) with TDR and/or double-dose rifampin (DDR) in human tuberculosis treatment. The primary outcome was pooled incidence rate ratio (IRR) of severe adverse events (SevAEs) between participants who received TDR and those who received SDR. Pooled relative risk (RR) of death was…
Qinglin Cheng, Ping Chen, Ruoqi Dai, Qingjun Jia, Xuexin Bai, et al.
**BACKGROUND:** Tuberculosis (TB) treatment remains a critical global health challenge, as traditional standard of care (SoC) approaches face limitations in accessibility and efficacy. While digital health technologies (DHTs) offer promising solutions to address these gaps, limit…
Ravindra Kumar Garg, Rajiv Garg, Akshaya Anand Agrawal, Sanjay Singhal, Raza Abbas Mahdi
Tuberculosis (TB) in pregnancies conceived via in vitro fertilization (IVF) presents unique diagnostic and management challenges, especially in TB-endemic regions. This systematic review synthesizes evidence on maternal and neonatal TB outcomes after IVF. We conducted a syst…
Yaquta Nur Mohamud, Wanna Chaijaroenkul, Kesara Na-Bangchang
…multifaceted roles of γδ T cells in malaria and tuberculosis (TB) with an emphasis on subset-specific dynamics and functional plasticity. In malaria, γδ T cells, particularly Vγ9Vδ2+ cells, are rapidly activated upon infection with Plasmodium f…
Wenmei Zhao, Wai Yan Min Htike, Yiu-Wing Kam
**BACKGROUND:** Tuberculosis (TB) remains a major public health challenge in China and worldwide, with smoking being a key modifiable risk factor. Given China's large population and rising smoking rates, this paper aims to examine the link between smoking and TB incidence. **MET…
Yonela Faith Ndlangalavu, Carmen Sue Christian
**INTRODUCTION:** Many patients with tuberculosis (TB) suffer from a huge economic burden, even though TB services are often provided free of charge at the point of care. Costs can create significant barriers, hindering patients' access to TB treatment. These costs include direct…
Anand Kumar Maurya, Sabir Ali, Shaina Gaikwad
**BACKGROUND:** Tuberculosis (TB) remains a major infectious cause of morbidity and mortality worldwide and is influenced by both environmental exposures and host genetic factors. Macrophage migration inhibitory factor (MIF), a proinflammatory cytokine, plays an important role in…
Mona S Mohamed, Miranda Zary, Cedric Kafie, Chimweta I Chilala, Shruti Bahukudumbi, et al.
**BACKGROUND:** Incomplete tuberculosis (TB) treatment adherence may lead to unsuccessful treatment and relapse. Digital adherence technologies (DATs) may allow more person-centric approaches for supporting treatment adherence. We conducted a systematic review (PROSPERO- CRD42022…
Pravachana Malakapogu, Tejaswini Baral, Kavitha Saravu, Mohan K Manu, Chiranjay Mukhopadhyay, et al.
**BACKGROUND:** Tuberculosis (TB) and diabetes mellitus (DM) are major global health concerns that frequently coexist, particularly in low- and middle-income countries. This dual burden negatively affects disease progression and outcomes. The patient care interventions have demon…
Nadira Aitambayeva, Altyn Aringazina, Laila Nazarova, Kamila Faizullina, Magripa Bapayeva, et al.
**BACKGROUND:** Stigma associated with tuberculosis (TB) continues to undermine patient well-being, treatment adherence, and public health goals and objectives. This study aims to systematically review the literature to identify and synthesize TB stigma reduction interventions pu…
Usha Nayak, Tejaswini Baral, Sonal Sekhar Miraj, Mohan K Manu, Muralidhar D Varma, et al.
**BACKGROUND:** Female genital tuberculosis (FGTB) continues to be a significant problem worldwide. Endometrial biopsy (EB) is the most effective sample for detecting FGTB. However, biopsy is invasive and causes unwarranted suffering. Furthermore, a few studies have investigated …
Ramona Cioboata, Mihai Olteanu, Denisa Maria Mitroi, Simona-Maria Roșu, Maria-Loredana Tieranu, et al.
Chronic obstructive pulmonary disease (COPD) and tuberculosis (TB) increasingly co-occur in low- and middle-income countries and aging populations. Prior pulmonary TB is a robust, smoking-independent determinant of COPD and is linked to persistent systemic inflammation, endotheli…
Mufti As Siddiq M Irzal, Tri Yunis Miko Wahyono, Putri Novia Choiri Insani, Welstin Wemi Loa, Leopardo Alvalius Ngetwa
**BACKGROUND:** Tuberculosis (TB) continues to pose a major global health threat, particularly in low- and middle-income countries. An estimated 10.8 million people developed TB in 2023, corresponding to 134 cases per 100,000 population. The Southeast Asia region accounted for 45…
Ratnesh Sinha, Dewesh Kumar, Sharath Burugina Nagaraja, Mohammad Hifz Ur Rahman
**BACKGROUND:** Tuberculosis (TB) remains a significant public health challenge in India, particularly among vulnerable populations. The Saharia tribe, a Particularly Vulnerable Tribal Group (PVTG), faces a disproportionately high TB burden. This study aimed to systematically rev…
Michael Prodanuk, James W King, Jessie Cunningham, Ian Kitai, Pierre-Philippe Piché-Renaud, et al.
**BACKGROUND:** Current tuberculosis (TB) diagnostics have limited sensitivity in children, resulting in undiagnosed and untreated cases; host blood biomarkers have the potential to narrow this diagnostic gap. **OBJECTIVES:** To conduct a systematic review to identify host blood…
Sem Samuel Surja, Donnatella Valentina, Anita Devi Krishnan Thantry, Jonathan Christianto Subagya, Edho Yuwono, et al.
…mosis is often misdiagnosed as or coinfected with pulmonary tuberculosis (TB). This study aims to analyze the misdiagnosis or co-occurrence of published cases of pulmonary TB and pulmonary histoplasmosis. Cases of histoplasmosis with dissemination were excluded, as it affects oth…
Hui Ming, Biao Fu, Xiaogang Chen, Wenbing Hu, Hui Yu
**OBJECTIVE:** To systematically evaluate the incidence of tuberculosis (TB) in cancer patients treated with immune checkpoint inhibitors (ICIs) and compare the risk of TB between ICI-treated and non-ICI-treated cancer patients, so as to provide evidence-based support for TB prev…
Rechel Shrisunder, Manesh Muraleedharan, Sammita Jagdish Jadhav, Dwight Figueiredo
**BACKGROUND:** India aims to eliminate tuberculosis (TB) by 2025. Despite ongoing efforts to transform TB care, numerous factors contribute to the persistence of missing cases in India. To gain insight into this issue, we performed a comprehensive review to identify the factors …
Monica Mbabazi, David Patrick Kateete, Faith Nakazzi, Joanitah Nabwire Wandera, Naume Mutesi, et al.
**BACKGROUND:** Tuberculosis (TB) remains the leading cause of bacterial disease-related mortality worldwide. While Koch’s single-agent model has long guided TB diagnostics and treatment, metagenomic studies reveal a resident lung microbiome disrupted by TB and its orally …
Diana Chusna Mufida, Muhammad Farhan Hibatulloh, Muhammad Yusuf Fadhil, Deva Fitra Firdausa Anwar, Cinday Kinanti Pramusinta, et al.
**INTRODUCTION:** Tuberculosis (TB) remains a significant global health challenge despite numerous innovations in diagnostic methods. Accurate early identification is essential for effective TB management and prevention of disease spread. **METHODS:** This study combined bibliom…