Showing 126–150 of 200 documents
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Mariana Gaspar Botelho Funari de Faria, Rubia Laine De Paula Andrade Gonçalves, Livia Maria Lopes, Elisangela Fransiscon Naves, Rafaele Oliveira Bonfim, et al.
…ed to analyse the repercussions of the COVID-19 pandemic on tuberculosis diagnosis indicators. A systematic review was conducted, examining studies published between 2020 and 2024 in Portuguese, English, or Spanish across five databases and Google Scholar. The search, performed i…
Hafsat U Ibrahim, Rayyan M Garba, Jameel I Ahmad, Kabiru Abdulsalam, Yasir N Jibril, et al.
**BACKGROUND:** Tuberculosis (TB) remains a leading cause of morbidity and mortality in Nigeria, particularly among people living with HIV (PLWH), who face significantly higher risks of developing active TB. Conventional diagnostic methods such as sputum smear microscopy and ches…
Morrish Obol Okello, Ivaan Pitua, James Nelson Okema, Doris Ekwem, Felix Bongomin, et al.
**BACKGROUND:** Drug-resistant tuberculosis (DR-TB) is a major public health challenge in Sub-Saharan Africa (SSA), worsened by high HIV prevalence and limited healthcare infrastructure. Bedaquiline, a cornerstone DR-TB treatment, is linked to QT interval prolongation, a risk fac…
Khasapane N G, Nkhebenyane S J, Ramatla T
**INTRODUCTION:** Bovine tuberculosis (bTB) is a chronic zoonotic disease affecting cattle of all age groups, including wild animals. The objective of this systematic review and meta-analysis was to provide a comprehensive and unbiased summary on the distribution of bTB and its a…
Julia Gallini, Urvashi B Singh, Madolyn Dauphinais, Sonali Sarkar, Madeline Carwile, et al.
**BACKGROUND:** Undernutrition is a leading risk factor for tuberculosis (TB) mortality and poor treatment outcomes. We evaluated the cost-effectiveness of providing in-kind nutritional support to impoverished persons with TB (PWTB) in India. **METHODS:** We developed a Markov m…
Xiuying Lv, Yuan Liu, Yan Li, Qi Zhang, Shiju Chen, et al.
…; inhibitors (TNFi) are established to increase the risk of tuberculosis (TB). However, the comparative risk across different TNFi agents remains poorly defined due to a lack of head-to-head comparative studies. This network meta-analysis (NMA) aimed to evaluate and compare the r…
Isabella van der Feltz, Haini Wen, Rob E Aarnoutse, Cecile Magis-Escurra, Elin M Svensson, et al.
…:** Drug concentrations at the site of disease in pulmonary tuberculosis (TB) remain limitedly available, while adequate exposures of anti-TB drugs in the lungs are required for sterilization of lesions. Intrapulmonary concentration data could benefit TB treatment optimization. W…
Nicola K Wills, Nevadna Singh, Coenraad F N Koegelenberg, Brian W Allwood
**PURPOSE OF REVIEW:** Tuberculosis (TB) is the leading cause of illness in people with HIV (PWH), with many survivors experiencing lasting lung damage. Post-TB lung disease (PTLD) is a challenge in this group, where additional respiratory insults, poor nutrition and healthcare a…
Agus Santosa, Neti Juniarti, Tuti Pahria, Raini Diah Susanti
Medication adherence is critical for successful tuberculosis (TB) treatment, yet non-adherence remains a major barrier to TB control globally. Digital adherence technologies (DAT) have emerged as promising tools to support adherence, but their effectiveness remains variably repor…
Paul W Bird, Daniel Pan, Kentaro Trerattanavong, Christopher A Martin, Christopher Holmes, et al.
…rom countries with high incidence of communicable diseases [tuberculosis (TB), HIV, and hepatitis B (HBV) and C (HCV)]; has increased the need for cost-effective early disease diagnosis programmes to improve outcomes. We aimed to synthesize and evaluate current literature on comm…
Rodolfo L Chávez-Domínguez, Mercedes Viettri, Martha Torres, Itzel A Corona-Galvan, Emilio Hernández-Diego, et al.
**INTRODUCTION:** The coexistence of tuberculosis (TB) and type 2 diabetes mellitus (T2DM) represents a growing global health challenge, particularly in low- and middle-income countries where TB remains endemic and T2DM prevalence is rising. Patients with T2DM exhibit a threefold…
Carla Florencia, Kevin Aprilio, Dian Ayu Eka Pitaloka, Rob E Aarnoutse, Ivan Surya Pradipta
**BACKGROUND:** Tuberculosis (TB) remains a major health challenge, with delayed detection accelerating its spread. Pharmacies are often the first contact for individuals with TB symptoms, yet their role in active case finding is underutilized. **OBJECTIVE:** This scoping review…
Bahram Heshmati, Sanaz Omidi, Younes Mohammadi
…ate the influence of alcohol, smoking, and substance use on tuberculosis (TB) treatment failure using a meta-analysis approach. **METHOD:** A comprehensive search strategy was developed and applied to three major databases: MEDLINE, Web of Science, and Scopus. Additionally, Goog…
Alicia E Madden, Sylvia K Ofori, Marian Budu, Emnet Sisay, Brian Dooley, et al.
**BACKGROUND:** Tuberculosis (TB) is a major global health concern, with long-term complications persisting even after successful treatment. Chronic pulmonary aspergillosis (CPA) is a progressive fungal disease that frequently develops in TB survivors, contributing to post-TB lun…
Dongmiao Yuan, Bo Xie, Zhe Pang, Kui Liu, Bin Chen
…ationships between air pollutants and the risk of pulmonary tuberculosis (PTB), possibly due to variations in exposure windows and limited attention to environmental modifiers such as greenness. However, few studies has systematically examined how short- and long-term exposu…
Yang Li, Ammar Saad, Zhen Feng, Shijia Ge, Lingyun Song, et al.
**INTRODUCTION:** Asymptomatic tuberculosis (TB) is increasingly recognised through active case finding and prevalence surveys. However, treatment strategies for this patient group remain poorly defined, and there is no consensus on optimal regimens, duration, or outcomes. **MET…
Sareh Bagheri-Josheghani, Zahra Rafat, Parivash Davoodian, Mehdi Hassani Azad, Afsaneh Karmostaji, et al.
Co-infection of tuberculosis (TB) and cryptococcosis as a consequence of impaired cell-mediated immune responses is accompanied by high mortality and morbidity rates. This study aimed to provide valuable insights into risk factors, diagnostic tests, and treatment methods used for…
Michael Prodanuk, Sarah L Silverberg, Pierre-Philippe Piché-Renaud, Daniel S Farrar, Jessie Cunningham, et al.
…ization (WHO) increased the recommended doses of first-line tuberculosis (TB) drugs for children. In this systematic review, we aimed to determine the proportion of children who developed adverse events (AEs) on first-line TB treatment and determine whether a change in toxicity w…
Katriina Willgert, Molly Cliff, Stefanie Meinke, Davide Messina, Donald M Broom, et al.
…re most effective in reducing the burden of disease. Bovine tuberculosis (bTB) is a major disease in cattle, but its impact remains poorly characterised in many contexts and production systems. To support the development of policies for accelerated bTB control, we conducted a sys…
Chieh-Yin Wu, Chu-Chang Ku, Christopher Finn McQuaid, Knut Lönnroth, J Peter Cegielski, et al.
**BACKGROUND:** Nutrition is a critical determinant of tuberculosis (TB), providing a protective effect at high body mass index (BMI) and incurring an increased risk of TB disease at low BMI. Global nutritional transition and interventions to end hunger could directly affect the …
Yahya Shadi, Esmaeil Khedmati Morasae, Salman Khazaei, Mahshid Nasehi, Saeed Sharafi, et al.
**BACKGROUND:** Tuberculosis (TB) is a leading cause of disability and mortality in many countries and is the leading cause of death from an infectious agent worldwide. While TB is a curable and preventable disease, health systems' ineffectiveness in case finding and appropriate …
Kylie Tingley, Angela Li, Emily L MacLean, Becky Skidmore, Nawal Maredia, et al.
**BACKGROUND:** Tuberculosis (TB) remains a global health threat, with millions of new infections annually. While most infected individuals remain asymptomatic, a subset progresses to active disease. Effective tests predicting TB progression are urgently needed to enhance prevent…
Svetlana Degtyareva, Yohhei Hamada, Rebecca F Baggaley, Nasser Hassan, Santino Capocci, et al.
**BACKGROUND:** Tuberculosis (TB) incidence and mortality in people living with HIV can be reduced by TB preventive treatment (TPT). However, low levels of screening and uptake, poor adherence, and loss to follow-up considerably reduce its effectiveness. We therefore aimed to ass…
Jiaqi Pu, Shouquan Wu, Jian-Qing He
…ids in patients with human immunodeficiency virus (HIV) and tuberculosis (TB) remain controversial. **METHOD:** PubMed, Embase, Web of Science, and the Cochrane Database were searched on 19 September 2024. The primary outcome was all-cause mortality, whereas secondary outcomes i…
Matthew Willis, Joelle Van de Wetering, Heynes Brown, Ewelina Julia Barnowska, Sophie Cw Stuetzle, et al.
**BACKGROUND:** Pediatric tuberculosis (TB) is a significant public health concern in India, contributing to 28% of the global pediatric TB burden. Despite its impact on child health, strategies to control TB have inadequately addressed pediatric cases, resulting in suboptimal ma…