Showing 126–150 of 200 documents
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AbdulAzeez Lawal, Abimbola Hussein, Simon Tiberi, Heinke Kunst
**BACKGROUND:** Adherence to tuberculosis (TB) treatment is essential in improving treatment outcomes and reducing TB-related mortality. People living with HIV (PLWH) are at a higher risk of developing and dying from TB. This systematic review aims to identify barriers and enable…
Eliza Miranda Ramos, Carolina Braga Sisti, Sérgio Beltrão de Andrade Lima, Emerson Luiz Lima Araújo, Lúcia Dias da Silva Guerra, et al.
**INTRODUCTION:** Tuberculosis (TB) remains a major public health problem in South America, disproportionately affecting vulnerable populations, such as the homeless population (HP). **OBJECTIVE:** To synthesize, through a systematic review with meta-synthesis, the scientific ev…
Pablo Troop, Brenna Keam, Caroline Mullen, Julius Nyerere Odhiambo
**INTRODUCTION:** Tuberculosis (TB) is a notable public health issue in sub-Saharan Africa (SSA), disproportionately affecting vulnerable populations such as nomads. Their migratory lifestyles limit consistent access to TB diagnostic and treatment services, leading to delays in d…
Yuxiao Ling, Songhua Chen, Yu Zhang, Qian Wu, Ke Yang, et al.
…ent is an important measure to interrupt the development of tuberculosis (TB) in people with latent tuberculosis infection (LTBI), which is among the key elements of TB prevention and control in the future. However, the implementation of preventive treatments has been affected by…
Anuj Ajayababu, Martin Hoenigl, Animesh Ray
…ssically described in asthma and cystic fibrosis, pulmonary tuberculosis (PTB) with post-tubercular lung disease (PTLD) has been reported as a likely predisposing factor. It, however, has not been reviewed systematically, which we aimed to achieve in the current systematic review…
Yuxiao Ling, Min Wang, Songhua Chen, Qian Wu, Yu Zhang, et al.
**BACKGROUND:** The burden of tuberculosis (TB) is increasingly borne by older adults. Several studies have investigated the prevalence of latent tuberculosis infection (LTBI) in special populations. However, the global estimates of the prevalence of LTBI in older adults are uncl…
Jirarat Songsri, Jongkonnee Thanasai, Jitbanjong Tangpong, Anchalee Chittamma, Wiyada Kwanhian Klangbud
The early diagnosis of pulmonary tuberculosis (PTB) remains a global challenge. While serum adenosine deaminase (ADA) has been associated with tuberculosis-related immune activation, its consistency across different regions and laboratory methods remains unclear. This study aims …
Hongfang Lu, Jingang Wang, Xinyu Song, Xiaoqi Xiong
…elationship between the MCP-1-2518A/G gene polymorphism and tuberculosis susceptibility in the Chinese population. The aim of this study was to investigate whether MCP-1-2518A/G polymorphism is associated with susceptibility to TB in Chinese. **METHOD:** Publications addressing …
Abraham Tekola Gebremedhn, Kidist Bobosha, Yeabsira Alemu Fantaye, Melese Yeshambaw Teferi, Ziad El-Khatib, et al.
**BACKGROUND:** Post-tuberculosis lung disease (PTLD) is a major public health challenge in sub-Saharan Africa (SSA), where the burden of tuberculosis (TB) remains high. Only a few studies have reported the global burden of PTLD, and the associated factors of PTLD have been under…
M J Nasiri, D R Silva, F Rommasi, M M Zahmatkesh, Z Tajabadi, et al.
**INTRODUCTION AND OBJECTIVES:** Post-tuberculosis lung disease (PTLD), as other chronic respiratory disorders, may have infectious complications; some of them can be prevented with vaccinations. So far, no document has discussed the potential role of vaccination in PTLD. Therefo…
Derara Girma Tufa, Leta Adugna Geleta, Hiwot Dejene Dissassa, Erean Shigign Malka, Addisu Waleligne Tadesse, et al.
…* The dual burden of Human Immunodeficiency Virus (HIV) and Tuberculosis (TB) in children is leading to significant mortality. Although primary studies have reported wide ranges of mortality rates among HIV-TB co-infected children in various African countries, a comprehensive est…
Sanjay Singhal, Ranganath Ganga, Pulkit Gupta, Aneeket Rastogi, Shilpi Arya, et al.
…easing use of Linezolid for the treatment of drug-resistant tuberculosis, concerns have emerged about serious adverse effects, including optic neuritis. **OBJECTIVES:** To systematically review available evidence on the incidence reported in the cohort, onset, linezolid doses an…
Fanghui Xie, Rong Yao, Li Liang, Chuntao Wu, Yinping Hu, et al.
… best evidence for medication adherence management in adult tuberculosis (TB) patients, providing an evidence-based foundation for optimizing clinical practice. **METHODS:** Evidence-based questions were formulated using the PIPOST model. Following the '6S' model, 19 Chinese and…
Pranav Shivashankar, Praween Senanayake, Thomas Stephen Ledger, Nicholas Ngui
**BACKGROUND:** Thyroid tuberculosis abscesses (TTA) are rare manifestations of extrapulmonary tuberculosis, with the available literature consisting almost exclusively of individual case reports and small observational series. This systematic review aimed to evaluate current man…
Qing-Hua Gao, Hong-Bo Chen, Yun Huang, Shun-Li Cai, Li-Ping Chen, et al.
…gamma release assay (IGRA) to predict progression of latent tuberculosis (LTBI) to active tuberculosis. **METHODS:** We searched PubMed, Embase, Web of Science, and the Cochrane Library for cohort studies published until October 6, 2024, that used both IGRA and TST to detect LTB…
Janmejaya Samal, Ranjit Kumar Dehury, M Benson Thomas, Hari Singh
…fe, low medication adherence, progression to drug-resistant tuberculosis, and ultimately, mortality. **OBJECTIVES:** This study aimed to estimate the pooled prevalence of depression in TB patients and identify the predictors of depression in this population in India. **METHODS:…
Sonia Menon, Anthony D Harries, Riitta A Dlodlo, Gisèle Badoum, Mohammed F Dogo, et al.
**BACKGROUND:** Tuberculosis (TB) remains a major global health challenge, with() causing significant morbidity and mortality mainly in high-burden countries. Following exposure to, individuals may become infected, developing TB infection (TBI) through inhalation of the bacillus:…
Ya-Li Chen, Yu He, Victor Naestholt Dahl, Kan Yu, Yan-An Zhang, et al.
…f various bioinformatics tools for predicting Mycobacterium tuberculosis drug resistance. A systematic review of PubMed, Embase, Scopus, Web of Science, CINAHL and the Cochrane Library was performed to identify studies reporting the effectiveness of bioinformatic tools for predic…
Radwan Darwish, Maya Tama, Sidra Sharief, Osama Zeidan, Sara Mohammed Ahmed Rady, et al.
…sued guidelines for developing a non-sputum test for active tuberculosis (TB) diagnosis that exhibits similar performance characteristics to sputum-based diagnosis, salivary diagnostic techniques have gained prominence as potential screening tools or adjuncts to existing diagnost…
Ricardo Perea-Jacobo, Jose Luis Soto-Ledesma, Rafael Laniado-Laborín, Dora-Luz Flores, Rogelio Zapata-Garibay, et al.
…the available literature on the prevalence and incidence of tuberculosis in incarcerated populations in Latin America and the Caribbean, identifying regional patterns, data gaps, and key challenges and providing recommendations for strengthening TB control strategies within priso…
Ashutosh N Aggarwal, Ritesh Agarwal, Sahajal Dhooria, Perumal K Bhavani, Kuruswamy T Prasad, et al.
Standard rifampicin doses used to treat pulmonary tuberculosis lie at the lower end of drug exposure-response curve. We evaluated if higher daily rifampicin doses result in greater efficacy or harm. We searched literature databases for randomized controlled trials comparing effic…
XiaoBo Wei, Norhashimah Mohd Norsuddin, Hamzaini Bin Abdul Hamid, Mohd Imree Azmi, GuiLan Zhang, et al.
…MS:** Machine learning (ML) has shown promise in diagnosing tuberculosis (TB), but systematic evidence on its role in predicting and diagnosing drug-resistant tuberculosis (DR-TB) is lacking. This study integrates a systematic review and meta-analysis to consolidate ML's performa…
Pubet Weeranawin, Tanawat Geeratragool, Wanruchada Katchamart, Julajak Limsrivilai
**BACKGROUND/AIMS:** Diagnosis of intestinal tuberculosis (ITB) is challenging. Histopathology and microbiological examination remain the gold standard, but previous studies show varied diagnostic performance. We aimed to systematically evaluate the accuracy of tests to diagnose …
Tingting Li, Huanqing Liu, Qian Lei, Zhuhong You
**BACKGROUND:** Tuberculosis (TB) caused 1.23 million deaths in 2024, with accurate diagnosis hampered by population heterogeneity and limited biomarker generalizability. We developed an integrative framework combining multi-cohort transcriptomics and machine learning to identify…
Seetu Palo, Sarita Rawat, Debadutta Mishra, Monica Mishra
Female genital tuberculosis (FGTB) is a challenging extrapulmonary manifestation of tuberculosis, often presenting with nonspecific symptoms and a paucibacillary profile, complicating diagnosis. This systematic review and meta-analysis evaluated the diagnostic performance of vari…