Showing 76–100 of 200 documents
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Mohammad Yousef Alikhani, Fatemeh Khoobbakht, Salman Khazaei, Tahere Etesamifard, Sima Kazemi
…tic variant and an individual's susceptibility to pulmonary tuberculosis (TB). Nevertheless, the evidence from various studies is contradictory and has not yielded a consensus. This meta-analysis was therefore conducted to systematically assess the relationship between this speci…
Yulan Yang, Qiaolin Yu, Xia Zhao, Rong Yao, Jing Shen, et al.
…nts' illness experiences and needs are central to pulmonary tuberculosis management and have important implications for treatment engagement and health outcomes. This study addresses this gap by systematically synthesizing qualitative evidence to provide a comprehensive understan…
George N Okoli, Benjamin J Cowling, Nicole Askin, Diane M Harper, Paul Van Caeseele
**INTRODUCTION:** To thoroughly examine the risk of active tuberculosis and herpes zoster infections with tumor necrosis factor (TNF) inhibitor treatment in adults (≥18-year-olds) with autoimmune disease conditions. **METHODS:** A trial sequential analysis (TSA) informed …
Mengistu Abayneh, Ahmed Zeynudin, Yared Alemu, Teshome Degefa, Abdulhakim Abamecha, et al.
**BACKGROUND:** The spread of tuberculosis (TB), including strains resistant to at least rifampicin and/or isoniazid, remains a major public health problem in developing nations, yet few comprehensive and comparative data on TB have been produced. The aim of this systematic revie…
Muluwork Getahun, Getu Diriba, Michael Hailu, Amanuel Wondimu, Ayinalem Alemu
**BACKGROUND:** Mycobacterium tuberculosis lineages exhibit variability in geographic distribution, transmissibility, and disease phenotype. Ethiopia is one of the countries with the highest prevalence of tuberculosis. The aim of this study was to summarize the proportion of line…
Behailu Taye, Haile Tesfaye, Gemechu Churiso
…pid, accurate, and non-sputum point-of-care (PoC) assay for tuberculosis (TB), especially for people with HIV (PLHIV). The Fujifilm SILVAMP TB LAM (FujiLAM), a urine lipoarabinomannan assay, has shown promise for diagnosing TB in PLHIV. But diagnostic performances were inconsiste…
Neha Sylvia Walter, Varun Gorki, Bikash Medhi, Pramod K Avti
…efficacy, and structure-activity mechanisms of AMPs against tuberculosis and malaria, the world's leading killer infectious diseases, employing the AMP database (APD3) (till June 2025) and PubMed search (January 1965 to June 2025). The comprehension is well addressed by covering …
Majed Al-Mourgi, Anwar Shams, Majed Wasal Al-Morgi, Ziyad Al-Morgi
…lti-drug-resistant and extensively drug-resistant pulmonary tuberculosis are increasing, posing profound health concerns; therefore, surgical intervention is gaining popularity again. However, the effectiveness of surgical treatment needs to be reassessed. This study attempted to…
Xianni Wei, Ruina Cai, Xiaohong Wu, Yonglong Su, Siheng Lian, et al.
**PURPOSE:** Antituberculosis drug-induced liver injury (ATLI) is a common and serious adverse drug reaction of tuberculosis treatment. The impact of ATLI in patients with chronic hepatitis C is unclear. The aim of this study is to evaluate the prevalence of DILI in patients with…
Claudia Susana Pérez Guerrero, Tiago Augusto Cavalcante Oliveira, Willie Otávio Bueno Bernardi, Stephanie Ribeiro, Jeanne-Marie Stacciarini, et al.
**BACKGROUND:** Tuberculosis is an infectious, preventable and treatable disease that is socially determined. People experiencing homelessness represent a group that is highly vulnerable to this disease, presenting a challenge for its control and elimination. The aim of this revi…
Vrunda Tavkar, Ankita Goyal, Vishal Chopra, Kranti Garg, Siddharth Sharma
**BACKGROUND:** Anti-tuberculosis drug-induced liver injury (AT-DILI) is one of the significant adverse effects of first-line tuberculosis therapy, frequently resulting in treatment discontinuation. Genetic polymorphisms in N-acetyltransferase 2 (), a key enzyme in the metabolism…
Liai Peng, Yiqing Zhou, Min Wang, Zhipeng Zu, Qian Wu, et al.
Tuberculosis preventive treatment (TPT) is essential for pediatric tuberculosis control in children and adolescents. Evidence indicates most attrition occurs prior to TPT initiation rather than from post-initiation nonadherence. This study systematically evaluated TPT acceptance …
Salman Daneshi, Esmaeil Barkhori Mehni, Mohammad Kamali, Eshagh Barfar, Fatemeh Bagher Barahouei, et al.
**INTRODUCTION:** Drug-resistant tuberculosis (DR-TB) is an increasing public health concern in Iran, with multidrug-resistant tuberculosis (MDR-TB) posing significant challenges to disease control efforts. This study examines the prevalence of DR-TB in Iran from January 2000 to …
Nakwon Kwak, Joong-Yub Kim, Areum Han, Catherine Berry, Maria Beumont, et al.
…d for treating multidrug-resistant and rifampicin-resistant tuberculosis remains unclear. We conducted an individual patient data meta-analysis to determine the optimal linezolid dosing strategy. **METHODS:** We searched for randomised controlled trials and prospective cohort st…
Daniel Souza Sacramento, Samantha Adiely Alecrim Mendonça, Altair Seabra de Farias, Vanderson Sampaio
Digital solutions are essential for eliminating tuberculosis as a public health problem. They can be applied across all stages of patient care, health surveillance, program management, workforce development, and community engagement. In this study, we aimed to identify and map di…
Ana Beatriz Marques Valença, Diogo Henrique Mendes da Silva, Melisane Regina Lima Ferreira, Paula Daniella de Abreu, Rubia Laine de Paula Andrade-Gonçalves, et al.
…ure on the use of Rapid Molecular Tests in the diagnosis of tuberculosis in people experiencing homelessness. this is a scoping review guided by the Joanna Briggs Institute and the Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews. A…
Emy Oktaviani, Kusnandar Anggadiredja, Lia Amalia
: The use of linezolid in drug-resistant tuberculosis has shown good effectiveness but has a high risk of adverse drug reactions (ADRs). Linezolid-related ADRs have been widely reported and may affect their therapeutic effect. This systematic review aimed to describe linezolid-re…
Aleka Aemiro, Abayeneh Girma, Getachew Alamnie, Demsew Beletew, Amere Genet
…erable to opportunistic bacterial infections, which include tuberculosis and pneumonia. This systematic review and meta-analysis looked at the pooled prevalence of opportunistic bacterial infections among people living with HIV in different regions of Ethiopia. **METHODS:** By l…
Deresse Daka, Belay Tessema, Awelani Mutshembele, Amir Alelign, Wubet Birhan, et al.
…lly transmissible. NTM infections are often misdiagnosed as tuberculosis (TB), especially in Ethiopia, where data on prevalence is scarce. This research aims to analyze NTM isolation from pulmonary samples and other specimens used in pulmonary tuberculosis (PTB) diagnosis among p…
Mingyang Qin, Yanhua Wen, Shanshan Li, Song Li, Xuming Li, et al.
**UNLABELLED:** Tuberculosis (TB) remains a major global health challenge. The close relationship between the microbiome and the host is becoming increasingly notable. While studies on the respiratory microbiome in pulmonary tuberculosis (PTB) exist, a comprehensive understanding…
Khalid Alyahyawi
Intestinal tuberculosis (ITB) is a complex form of extrapulmonary tuberculosis characterized by nonspecific gastrointestinal symptoms and substantial overlap with conditions such as Crohn's disease and gastrointestinal malignancies. These similarities frequently lead to diagnosti…
Beatriz Bernava Sarinho, Inajara Rotta, Tácio de Mendonça Lima, Brígida Dias Fernandes, Patricia Melo Aguiar, et al.
…eutic interventions for the treatment of histoplasmosis and tuberculosis coinfections in patients with Human Immunodeficiency Virus (HIV) and Acquired Immunodeficiency Syndrome (AIDS), there are no reviews evaluating the efficacy, effectiveness, and safety of different regimens. …
Siddique Sehrish, Xue-Tong Liu, Wen-Bo Lou, Shu-Ying Zhang, Emad Beshir Ata, et al.
**BACKGROUND:** Bovine tuberculosis (bTB) primarily caused by, is a globally prevalent zoonotic infectious disease of cattle and other livestock and wildlife species. Pakistan is the fourth-largest milk-producing country in the world, with approximately 212 million animals. Lives…
Fernanda Souza, Ricardo Steffen, Marcia Pinto, Thiago Nascimento do Prado, Afranio Lineu Kritski, et al.
…:** The World Health Organization has recommended three new tuberculosis (TB) antigen-based skin tests (TBST) (Diaskintest®, C-TST®, Cy-TB®) for the diagnosis of tuberculosis infection (TBI). Household contacts (HHC) of people with pulmonary TB are at increased ris…
Xiaonan Geng, Fan Zhang, Ruichao Liu, Fuzhen Zhang, Ziwen Li, et al.
**BACKGROUND:** Drug-resistant tuberculosis (DR-TB) remains a formidable public health challenge, posing a significant threat to human life and health security. Comprehensive comparative evidence on the efficacy and safety of various DR-TB treatment strategies remains limited. Th…