Showing 26–50 of 151 documents
Sorted by hybrid relevance (keyword + semantic via RRF)
Peter Wadie, Bishoy Zakher, Khalid Elgazzar, Abdulhamid Alsbakhi, Abdul-Mohsen G Alhejaily
**BACKGROUND:** Artificial intelligence (AI) integrated with point-of-care imaging is a promising approach to expand access in settings with limited specialist availability. However, no systematic review has comprehensively evaluated AI-assisted clinical decision support across m…
Ying Gao, Wenjuan Ji, Qiuyan Chen
BackgroundDrug-resistant Mycobacterium tuberculosis strains have challenged efforts to combat tuberculosis (TB), a major global killer. C-reactive protein (CRP) shows promise as a biomarker for TB screening, particularly in HIV-positive cases, with demonstrated sensitivity and sp…
Pranav Shivashankar, Praween Senanayake, Thomas Stephen Ledger, Nicholas Ngui
**BACKGROUND:** Thyroid tuberculosis abscesses (TTA) are rare manifestations of extrapulmonary tuberculosis, with the available literature consisting almost exclusively of individual case reports and small observational series. This systematic review aimed to evaluate current man…
Liwei Yao, Caifang Bu, Lijun Xiang
**BACKGROUND:** Tuberculous lymphadenitis (TL) is a common case of extrapulmonary tuberculosis caused by Mycobacterium tuberculosis (MTB). The current use of nanopore sequencing in TL is limited. The aim of our study is to complete a systematic review and meta-analysis protocol t…
Ya-Li Chen, Yu He, Victor Naestholt Dahl, Kan Yu, Yan-An Zhang, et al.
To compare the diagnostic yield of various bioinformatics tools for predicting Mycobacterium tuberculosis drug resistance. A systematic review of PubMed, Embase, Scopus, Web of Science, CINAHL and the Cochrane Library was performed to identify studies reporting the effectiveness …
S Debulpaep, H Van Overschelde, L Pieters, A Soler-Garcia, A Noguera-Julian, et al.
<sec><title>BACKGROUND</title>Interferon-gamma release assays (IGRAs) have largely replaced the tuberculin skin test (TST) for diagnosing TB infection (TBI) in low-TB-burden countries, except in young children. This review assesses the diagnostic accuracy of IGRAs in children und…
Andressa Lorena Ieque, Carolina Trevisolli Palomo, Deborah de Castro Moreira, Jean Eduardo Meneguello, Letícia Sayuri Murase, et al.
Tuberculous meningitis (TBM) is one of the most severe clinical forms of tuberculosis (TB). Since epidemiological studies can contribute to TB control, we conducted a review and meta-analysis of epidemiological publications of adults TBM cases in countries with high incidence of …
Troy Kettle, Tricia M McKeever, Sherif Gonem, Grazziela Figueredo, Ilze Bogdanovica
**BACKGROUND:** There is increasing interest in the use of artificial intelligence (AI) to assist with respiratory diagnosis and risk prediction. Fuzzy logic is a form of AI that has the advantage of being transparent and interpretable, compared to alternatives such as deep neura…
Hadi Sahrai, Jamal Behnood, Mansoureh Baradaran, Amirreza Khalaji, Ali Norouzi, et al.
**BACKGROUND:** Distinguishing lung cancer (LC) from pulmonary tuberculosis (TB) on CT is difficult. We synthesized evidence on radiomics, clinical, and combined models for LC–TB discrimination. **METHODS:** PubMed, Web of Science, Embase, and Scopus were searched to Augu…
Lika Apriani, Harsimren Sidhu, Alexei Korobitsyn, Nazir Ismail, Dick Menzies
**BACKGROUND:** The WHO currently endorses several commercial Interferon Gamma Release Assays (IGRAs); policy updates are needed given the development of new tests. We conducted an updated systematic review and meta-analysis to compare sensitivity, specificity, and agreement of n…
Leeberk Raja Inbaraj, Mukesh Kumar Sathya Narayanan, Jefferson Daniel, Vignes Anand Srinivasalu, Adhin Bhaskar, et al.
**BACKGROUND:** Accurate and prompt diagnosis of tuberculosis in children is challenging due to non-specific clinical presentation and the low bacillary load of samples. Low-complexity manual nucleic acid amplification tests (LC-mNAATs) such as loop-mediated isothermal amplificat…
Malika Idayat, Elena von der Lippe, Nailya Kozhekenova, Oyunzul Amartsengel, Kamila Akhmetova, et al.
…h regard to drug-resistant strains. Point-of-care molecular diagnostics, improved algorithms, and expanded laboratory training show promise. Future research should focus on rapid biomarker-based diagnostics, field-deployable technologies for settings with limited resources, and A…
Boya Gou, Chuyao Zhang, Zhe Song, Zhen Huang, Shuihua Lu
**BACKGROUND:** Targeted next-generation sequencing (tNGS) is an adjunct tool endorsed by the World Health Organization (WHO) for tuberculosis diagnosis. The study aimed to investigate the diagnostic performance of tNGS across different clinical scenarios (populations, sample and…
Zohreh-Al-Sadat Ghoreshi, Mohammad Ali-Hassanzadeh, Habibeh Mashayekhi-Sardoo, Hedyeh Askarpour, Nasir Arefinia
**BACKGROUND:** Rapid and precise detection of Mycobacterium tuberculosis (MTB) is essential for effective management and control of tuberculosis. The diagnostic challenge is particularly acute for extrapulmonary TB, which accounts for approximately 15-20% of cases and often pres…
Laura Olbrich, Bada Yang, Hayley Poore, Alia Razid, Brittney Sweetser, et al.
**BACKGROUND:** Low-complexity automated nucleic acid amplification tests (LC-aNAATs) are molecular assays widely used to diagnose tuberculosis disease in children. The lateral flow urine lipoarabinomannan assay (LF-LAM) is recommended for use amongst children with HIV. Previous …
Stephanie Bjerrum, Bada Yang, Johanna Åhsberg, Laura Olbrich, Mathias Weis Damkjær, et al.
**BACKGROUND:** Low-complexity automated nucleic acid amplification tests (LC-aNAATs) are molecular World Health Organization (WHO)-recommended rapid diagnostic tests (also known as mWRDs) widely used to diagnose tuberculosis disease. The lateral flow urine lipoarabinomannan assa…
Seraphina Key, Michael Fook-Ho Lee, William Jiang, Zubair Hasan, Faruque Riffat
**BACKGROUND:** Submucosal laryngeal lesions may pose diagnostic uncertainty and mimic tumours. Although mycobacterium tuberculosis is the leading cause, non-tuberculous granulomas arise from multiple aetiologies. This paper presents a systematic review and case series to elucida…
Yusuf Wada, Hafeez A Afolabi, Ahmad Adebayo Irekeola, Kizito Eneye Bello, Chan Yean Yean, et al.
**BACKGROUND:** Latent tuberculosis infection (LTBI) remains a major public health challenge in Malaysia, yet prevalence estimates across population groups and settings are fragmented. This systematic review and meta-analysis aimed to synthesize available evidence and identify so…
Aboudou Habirou Kifouly, Orléanse Kouin, Géorcelin Alowanou, Obase Ngemani Bekindaka, Pierre Challaton, et al.
**INTRODUCTION:** Bovine tuberculosis (bTB), caused by, is a chronic zoonotic disease of major global importance, particularly in low- and middle-income countries where surveillance and control remain inadequate. **OBJECTIVES:** This systematic review and meta-analysis aimed to …
Behailu Taye, Haile Tesfaye, Gemechu Churiso
**BACKGROUND:** There is a global need for a rapid, accurate, and non-sputum point-of-care (PoC) assay for tuberculosis (TB), especially for people with HIV (PLHIV). The Fujifilm SILVAMP TB LAM (FujiLAM), a urine lipoarabinomannan assay, has shown promise for diagnosing TB in PLH…
Salman Daneshi, Esmaeil Barkhori Mehni, Mohammad Kamali, Eshagh Barfar, Fatemeh Bagher Barahouei, et al.
**INTRODUCTION:** Drug-resistant tuberculosis (DR-TB) is an increasing public health concern in Iran, with multidrug-resistant tuberculosis (MDR-TB) posing significant challenges to disease control efforts. This study examines the prevalence of DR-TB in Iran from January 2000 to …
Zhi-Lin Han, Yu-Yang Zhang, Jian Li, Shan Gao, Wei Liu, et al.
**BACKGROUND:** Pulmonary tuberculosis (PTB) remains a global public health challenge, with 10.8 million new cases reported in 2023. Early diagnosis is crucial for controlling its spread, yet traditional sputum-based tests face limitations in turnaround time and resource availabi…
Michael Prodanuk, James W King, Jessie Cunningham, Ian Kitai, Pierre-Philippe Piché-Renaud, et al.
**BACKGROUND:** Current tuberculosis (TB) diagnostics have limited sensitivity in children, resulting in undiagnosed and untreated cases; host blood biomarkers have the potential to narrow this diagnostic gap. **OBJECTIVES:** To conduct a systematic review to identify host blood…
Seetu Palo, Sarita Rawat, Debadutta Mishra, Monica Mishra
Female genital tuberculosis (FGTB) is a challenging extrapulmonary manifestation of tuberculosis, often presenting with nonspecific symptoms and a paucibacillary profile, complicating diagnosis. This systematic review and meta-analysis evaluated the diagnostic performance of vari…
XiaoBo Wei, Norhashimah Mohd Norsuddin, Hamzaini Bin Abdul Hamid, Mohd Imree Azmi, GuiLan Zhang, et al.
**BACKGROUND AND AIMS:** Machine learning (ML) has shown promise in diagnosing tuberculosis (TB), but systematic evidence on its role in predicting and diagnosing drug-resistant tuberculosis (DR-TB) is lacking. This study integrates a systematic review and meta-analysis to consol…