Showing 1–25 of 31 documents
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Soraya Permata Sujana, Fadilah Habibul Hamda, Mufti As Siddiq, Yuniko Ibnu Latif, Al Asyary
**BACKGROUND:** Tuberculosis is one of the leading causes of death from infectious diseases in the world, with approximately 25% of the global population having latent tuberculosis infection. Secondhand smoke exposure has been recognised as a significant risk factor in the develo…
Abdulaziz S Aljibali
…GROUND:** Chest radiography is routinely used during latent tuberculosis infection (LTBI) evaluation to exclude active disease. **METHODS:** PubMed and google scholar were searched for studies reporting chest radiographic abnormalities among individuals with LTBI in Gulf Coopera…
Anna Starshinova, Adilya Sabirova, Igor Kudryavtsev, Artem Rubinstein, Leonid P Churilov, et al.
**INTRODUCTION:** Tuberculosis infection remains one of the most dangerous and difficult to diagnose diseases. To date, issues related to the early diagnosis of tuberculosis remain unresolved, which is particularly important for its detection in high-risk groups. The detection of…
Karthikeyan Sundaram, Leela Kagithakara Vajravelu, Ravichandiran Velayutham, Utpal Mohan
**BACKGROUND:** Tuberculosis is a contagious disease that ranks among the top ten killers of humans worldwide. Mycobacterium tuberculosis is an etiological agent of tuberculosis. The prognosis of tuberculosis in patients with autoimmune diseases is high due to treatment with anti…
Zipporah Dery, Celso Pagatpatan, Margel Bonifacio
…cilitators of the use of digital adherence technologies for tuberculosis treatment. The review will focus on the human factors that support the use of these technologies in tuberculosis treatment. **INTRODUCTION:** More than 10 million people are infected with tuberculosis every…
Shyamkumar Sriram, Tareq Abualfaraj, Manal Ali Alsharif, Marwa Zalat, Saad Madani Alawfi, et al.
Patients with latent tuberculosis infection are mainly asymptomatic, but they still carry a notable risk of developing active TB, particularly when the host becomes immunosuppressed. Hence, appropriate diagnosis and management for LTBI are essential. Tuberculin skin test (TST) an…
Liai Peng, Yiqing Zhou, Min Wang, Zhipeng Zu, Qian Wu, et al.
Tuberculosis preventive treatment (TPT) is essential for pediatric tuberculosis control in children and adolescents. Evidence indicates most attrition occurs prior to TPT initiation rather than from post-initiation nonadherence. This study systematically evaluated TPT acceptance …
Unjali P Gujral, Peijue Huangfu, Amanuel A Kisho, Elizabeth S Limb, Dzigbordi Kamasa-Quashie, et al.
**BACKGROUND:** Tuberculosis (TB) remains a major public health challenge, with 10.8 million people developing TB in 2023. Diabetes mellitus (DM) is associated with an increased risk of TB and adverse TB outcomes. The prevalence of DM is rising, especially in regions of the world…
Felipe T Lima, Ricardo C Castro, Francisco R Javier, Caroline Fontanari, Valdes R Bollela, et al.
During tuberculosis (TB), organ-specific immune responses and intracellular pathways play critical roles in disease progression and prognosis. Identifying genes that regulate these immune mechanisms remains a key challenge in improving TB management strategies. To investigate gen…
Ida A A Parwitha, Vania D Djunaidy, Sofa D Alfian, Hari Setyowibowo, Ivan S Pradipta
Despite its importance in global TB elimination, tuberculosis preventive treatment (TPT) remains underutilized. Psychosocial barriers significantly contribute to this issue. This systematic review aims primarily to synthesize psychosocial interventions to improve the initiation o…
Yuxiao Ling, Min Wang, Songhua Chen, Qian Wu, Yu Zhang, et al.
**BACKGROUND:** The burden of tuberculosis (TB) is increasingly borne by older adults. Several studies have investigated the prevalence of latent tuberculosis infection (LTBI) in special populations. However, the global estimates of the prevalence of LTBI in older adults are uncl…
Yuxiao Ling, Songhua Chen, Yu Zhang, Qian Wu, Ke Yang, et al.
…ent is an important measure to interrupt the development of tuberculosis (TB) in people with latent tuberculosis infection (LTBI), which is among the key elements of TB prevention and control in the future. However, the implementation of preventive treatments has been affected by…
Jincheng Huang, Jinjie Xia, Binxue Hong, Can Zhang, Li Zhao, et al.
… aims to evaluate the risk factors and prevalence of latent tuberculosis infection (LTBI) in patients with rheumatic diseases. **METHODS:** Databases including PubMed, EMBASE, Web of Science, Cochrane Library, CNKI, Vip, and Wanfang were searched. Data extraction was performed i…
Qing-Hua Gao, Hong-Bo Chen, Yun Huang, Shun-Li Cai, Li-Ping Chen, et al.
…gamma release assay (IGRA) to predict progression of latent tuberculosis (LTBI) to active tuberculosis. **METHODS:** We searched PubMed, Embase, Web of Science, and the Cochrane Library for cohort studies published until October 6, 2024, that used both IGRA and TST to detect LTB…
Sonia Menon, Anthony D Harries, Riitta A Dlodlo, Gisèle Badoum, Mohammed F Dogo, et al.
**BACKGROUND:** Tuberculosis (TB) remains a major global health challenge, with() causing significant morbidity and mortality mainly in high-burden countries. Following exposure to, individuals may become infected, developing TB infection (TBI) through inhalation of the bacillus:…
Namitha, Priyanka, Monika Sharma, Sadhna Sharma
**BACKGROUND:** Globally, tuberculosis (TB) is a significant health issue, and both latent and active TB pose considerable public health risks. Adequate vitamin D is crucial in immune regulation, and its deficiency raise the odds of developing TB. There is still uncertainty about…
Shunli Cai, Tianwei Yan, Yutian Yang, Xin Guo, Xiang Li, et al.
…(BCG) vaccination is well established for preventing severe tuberculosis (TB) in children; however, its effectiveness in reducing the progression of latent TB infection (LTBI) to active disease remains uncertain, particularly in real-world contact settings. **METHODS:** We condu…
Qin Chen, Ningjun Ren, Shengya Liu, Zixin Qian, Mengdie Li, et al.
**BACKGROUND:** Tuberculosis (TB) continues to pose a significant global public health threat, particularly among migrant populations. Screening policies exist in many receiving countries but differ markedly, and there is limited pooled evidence on TB and latent TB infection (LTB…
Aminat Y Saula, Muge Cevik, Jacqueline M Cliff, Katharina Ronacher, Ruth Bowness
**BACKGROUND:** Tuberculosis (TB) remains a leading cause of infectious disease mortality worldwide, and the rising prevalence of diabetes mellitus (DM) represents a major obstacle to TB control. DM increases susceptibility to TB, worsens disease severity, delays treatment respon…
Nyimas Maida Shofa, Nurike Setiyari Mudjari, Rusdiyana Ekawati, Arianti Arianti, Annisa Zahra Mufida, et al.
…s disease (CD) using anti-tumour necrosis factor therapy in tuberculosis (TB)-endemic regions poses major clinical challenges due to the risk of latent TB infection reactivation. This bibliometric-systematic literature review synthesised evidence from 17 peer-reviewed studies (20…
Jelkeba Bali Weyesa, Mengistu Legesse, Balako Gumi, Girmay Medhin, Ketema Tolossa, et al.
Early detection of latent tuberculosis (TB) is crucial for prevention. However, there is a debate over the effectiveness of QuantiFERON tests versus tuberculin skin tests. This meta-review critically evaluated QuantiFERON (QFT) tests for latent TB detection. This diagnostic …
Nihal Altunisik, Sibel Altunisik Toplu, Dursun Turkmen
…cination rates. **METHODS:** A clinical scenario on latent tuberculosis management in psoriasis patients on IL-17/23 inhibitors was defined. To establish a reference standard, references (n=74) from the two most recent and comprehensive systematic reviews on the topic were scree…
Kar Mun Chong, Yi Wye Lai, Stanley Angkodjojo, Peter Pak Moon Cheung, Li-Ching Chew, et al.
**INTRODUCTION:** Tuberculosis (TB) remains endemic in Asia, with latent TB infection (LTBI) being prevalent, especially among older adults. People with rheumatic diseases (PRD) who are treated with tumour necrosis factor-alpha inhibitors (TNF-I) are at increased risk of TB react…
Zikang Sheng, Lin Zeng, Yue Zhang, Hongbin Chi, Xiaoyan Gai, et al.
**OBJECTIVES:** Tuberculosis (TB) is a common cause of infertility in humans, especially in regions with high TB prevalence. However, the impact of latent TB infection (LTBI) on pregnancy outcomes following assisted reproduction in patients with infertility remains unclear. This …
Helio Rzetelna, Paula Santo, Heitor Siffert Pereira de Souza, Jacob Nichols, Cyrla Zaltman
…lpha (anti-TNF) therapy are at increased risk of developing tuberculosis (TB), making screening before anti-TNF initiation mandatory. Repeated screening during treatment is not yet recommended because of a lack of studies to support this practice. We aimed to determine the propor…