Showing 1–12 of 12 documents
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Charles Lukanga Kimera, Fredrick Sinyinza, Linda Ndesipandula Lukolo
…suffering and death for many years. Until the 1980s, before HIV, TB was the leading cause of death among infectious diseases. A 23-year-old nulliparous woman presented to our gynaecology clinic with post-coital bleeding and irregular menstrual periods. Review of her medical and s…
Anna Starshinova, Igor Kudryavtsev, Artem Rubinstein, Irina Dovgalyuk, Anastasia Kulpina, et al.
…ctions involving mucous membranes, including salmonellosis, HIV, and acute viral respiratory infections. It is essential to investigate the role of BCG in various applications; however, this exploration should not detract from its main protective benefits against tuberculosis (TB…
Yi Hao Wong, Hai Tarng Chong, Ting Huey Hu, Catherine Wei Min Ong
…r potential benefits in TB-associated comorbidities such as HIV and diabetes mellitus, and key findings from randomized controlled trials. However, transitioning these agents into standard clinical practice requires large-scale, stratified Phase III trials. Integrating HDTs along…
Şule Kızıltaş, Aylin Babalık
… million people died from TB, including 214,000 people with HIV [1]. The clinical features of tuberculosis vary widely. Patients may present with pulmonary involvement, extrapulmonary involvement (more rarely), or both. Early, accurate diagnosis and treatment of TB are of critica…
Rafael Laniado-Laborı́n
…e advanced age, female gender, immunosuppression (including HIV) and chronic comorbidities. Symptoms and signs are usually non-specific, and except for miliary forms, the chest radiograph might be normal; therefore, the diagnosis of EPTB is frequently delayed with the consequent …
Rafael Laniado-Laborín
…ar, there were 1.3 million deaths due to tuberculosis among HIV-negative people; children accounted for 15% of all deaths from TB, a percentage higher than their share of estimated cases. Clinical presentation of pulmonary TB varies according to the age of the patient. Infants fr…
Salma Madihi, Achraf Aainouss, Mly Driss Ei Messaoudi, Abdelouaheb Benani
…burden, the leading cause of death among people living with HIV, and one of the main causes of death linked to antimicrobial resistance. The World Health Organization (WHO) launched in 2015 the End TB Initiative that aims to reduce TB cases and deaths by 2035. However, despite so…
Ashfaque Ansari, L. V. Manjusha Bavisetty
…n India, particularly in immune-compromised individuals and HIV patients. Tuberculosis is caused by Mycobacterium tuberculosis, It remains the most common infectious disease affecting the lungs in India to date, and can present with various extrapulmonary manifestations. One rare…
Siddharth Sekhar Sethy, Gagan Deep, P V Sudhakar, Tarun Goyal, Pankaj Kandwal, et al.
…ulosis, probably only next to cutaneous tuberculosis in non-HIV patients. Considering the low incidence of primary osteoarticular tuberculosis without pulmonary tuberculosis, we hypothesise that there is an element of tissue-specific immunity against tuberculosis in the body, whi…
Rajiv Garg, Shubham Shukla, Ravindra Kumar Garg
…fic populations-such as extremes of age, people living with HIV, and elderly individuals-presents additional complexities due to atypical presentations and altered immune responses. This review comprehensively discusses the multifaceted challenges in diagnosing CNS TB and the eme…
Qibin Liu, Xiyong Dai, Shuang Wei
… immunodeficiencies such as SCID, MSMD, CGD, or symptomatic HIV infection. Implementation of universal newborn screening for severe combined immunodeficiency (SCID) using the T-cell receptor excision circle (TREC) assay now enables prospective identification and deferral of these…
Olga Adriana Căliman-Sturdza
…e best intensified therapy, particularly in children and in HIV co-infection.