Showing 1–14 of 14 documents
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Akihiro Ohkado, Seiya Kato
Epidemiology of TB provides important information for clinical diagnosis. The risk of TB infection and disease development depends on exposure to bacilli, i.e., contact with infectious TB patients, host factors such as comorbidities, and socio-economic conditions. TB was called a…
Defne Yigci, İlker Kayı, Yusuf Ziya Demiroğlu, Murat Kutlu, Zeki Kılıçaslan, et al.
… health challenge. We provide an overview of the current TB epidemiology in Turkey, highlighting key findings related to TB incidence, diagnostic challenges, and treatment outcomes. **RESULTS:** A gradual decline in TB incidence in Turkiye has been observed over recent year…
Rafael Laniado-Laborı́n
Globally, tuberculosis is one of the top 10 overall causes of death, the leading cause of death from a single infectious agent, and the principal cause of death among subjects living with human immunodeficiency virus infection. The United Nations and the World Health Organization…
Keertan Dheda, Aliasgar Esmail, Anzaan Dippenaar, Robin M. Warren, Jennifer Furin, et al.
…nical perspective and focuses on the clinical and molecular epidemiology, diagnosis, and clinical management of drug-resistant tuberculosis (DR-TB). Tuberculosis (TB) is far from eradicated and remains the foremost single infectious disease killer worldwide. Molecular epidemiolog…
S. Jonathan Chapman, Grace V. Robinson, Rahul Shrimanker, Chris D. Turnbull, John Wrightson
Includes: Tuberculosis: epidemiology and pathophysiology, first-line anti-TB drugs, TB chemotherapy with comorbid disease, multidrug-resistant TB (MDR-TB), latent TB infection, TB and anti-TNF-α treatment, disseminated BCG infection (BCGosis), future developments in TB, non-tube…
Hossein Jooya, Sama Yavari, Maryam Meskini, Seyyed Mohammad Amin Mousavi-Sagharchi, Seyed Davar Siadat, et al.
Tuberculosis (TB) exerts profound detrimental impacts on global human populations. This infectious disease is primarily caused by(MTB), a highly adapted pathogen that undergoes rapid genomic evolution, enabling it to acquire resistance to targeted antimicrobial agents. The emerge…
H Manisha Yapa, Emily L-H MacLean, Nicolas A Menzies, Peter J Dodd, Anna Dean, et al.
…priorities, we conducted a narrative review of global DR-TB epidemiology and strategies for DR-TB prevention, diagnostics, and treatment. Gaps remain in DR-TB diagnosis, TB drug susceptibility testing (DST), and treatment. The review also shows that DR-TB causes significant post-…
Andrea Monserrat Negrete-Paz, Gerardo Vázquez-Marrufo, Ma Soledad Vázquez-Garcidueñas
…ons have demonstrated transformative potential in molecular epidemiology, drug resistance prediction, and virulence profiling. This perspective underscores a shift toward diversity-inclusive approaches, with integration of machine learning and standardization of analytical protoc…
Nandini Gupta, Ramesh K. Goyal, Bhoomika M. Patel
…he diverse range of technologies such as molecular biology, epidemiology, and bioinformatics requires working in a synchronous way to reduce the despair caused by such a lethal disease.
Gerald Mboowa
…ities, and policy considerations necessary to embed genomic epidemiology within national TB control programs, particularly in high-burden, resource-constrained settings.
Phool Chandra, Prashant Kumar, Surya Nath Pandey, Manoj Kumar Bisht
Tuberculosis (TB), developed by the Gram-positive bacterium Mycobacterium tuberculosis, is the prominent cause of demise globally due to high antibiotic resistance. Approximately 1.5 million people deceased of TB in 2020 worldwide. The causative pathogen of tuberculosis spreads m…
Risha Hazarika, Sanjukta Patra
…c surveillance. This review focuses on the molecular basis, epidemiology, and diagnostic challenges associated with non-RRDR mutations, highlighting the need to upgrade diagnostic platforms and strengthen genomic surveillance to ensure early, accurate detection of rifampicin-resi…
Ingrid Burkhardt, Florian Götzinger, Lahia Iipumbu, Elizabeth Whittaker, Gunar Günther, et al.
…ound information and practical guidance on the disease, the epidemiology, diagnostics, treatment options, and post MDR-TB sequalae. We also address the special circumstances of adolescents, comorbidities, and the socioeconomic impact of MDR-TB. PubMed was searched for suitable ar…
Yan Zhang, Dian Yuan, Hua-Li Wang, Chao-Qiong Zhou, Yan-Qun Liu, et al.
Tuberculosis (TB) remains a major global public health challenge, and its control efforts are increasingly complicated by the rising prevalence of drug-resistant TB (DR-TB). Rifampicin (RIF), a cornerstone of first-line anti-TB treatment regimens, plays a pivotal role in TB thera…