Showing 1–9 of 9 documents
Sorted by hybrid relevance (keyword + semantic via RRF)
Rajwinder Kaur, Varsha Sharma, Anju Kumari
Female genital tuberculosis (FGTB), a form of extrapulmonary tuberculosis caused by Mycobacterium tuberculosis (MTB), is an under-recognized but significant cause of female infertility, particularly in developing countries. It primarily spreads through the hematogenous route and …
Charisse Mandimika, Gerald Friedland
This chapter discusses the global and local epidemiology, clinical features, and recent selected advances and challenges in the prevention and treatment of TB/HIV disease. Drug-susceptible and drug-resistant tuberculosis (TB) and human immunodeficiency virus (HIV) epidemics are a…
Kevin Flores-Lovon, Edwin Herrera, Paola Salinas, Rodney Macedo
Individuals who have co-infection with COVID-19 and tuberculosis (TB) are more likely to have severe illness and higher mortality. Thus, we sought to review the biological, immunological, clinical, and epidemiological interactions between COVID-19 viral infection and Mycobacteriu…
Abraham Chorbajian, Ira Glassman, Akhila Swarna, Manvita Mareboina, Po-En Chen, et al.
…t TB screening before immunosuppression, attention to local epidemiology, and vigilance for NTM. Research priorities include prospective cohorts, mechanistic studies of mimicry and NOD2-TLR pathways, safety registries, and trials of screening and prophylaxis.
Eduarda Rabello, Fernanda de-Paris
Tuberculosis (TB) remains one of the leading causes of death from a single infectious agent worldwide, a burden further exacerbated by HIV co-infection and the increasing prevalence of drug-resistant strains. Although a wide range of laboratory diagnostic methods are currently av…
Florence Mutua, Ruey-Chyi Su, Terry Blake Ball, Sandra Kiazyk
The identification of a type I interferon-induced transcriptomic signature in active tuberculosis suggests a potential role for these interferons in the pathogenesis of tuberculosis. Comorbidities such as human immunodeficiency virus, diabetes, systemic lupus erythematosus, end-s…
Itai M Magodoro, Leigh A Kotze, Cari J Stek, Alexander West, Andrea Le Roux, et al.
…t host-directed therapies (HDT) in active TB. We review the epidemiology of TB, diabetes and their combined comorbidity, their immune and metabolic mechanisms and clinical relevance, as well as potential opportunities for general and targeted therapeutic intervention. **EXPERT O…
Egídio Torrado, Reinout vanCrevel, Ana Raquel Afonso, Diana Amorim, Raquel Duarte
…d treat for TBI. In the past decades, much new knowledge on epidemiology, risk factors and treatment of TBI has been gathered, which is summarised in this chapter. <bold>Cite as:</bold> Torrado E, vanCrevel R, Afonso AR, <italic>et al.</italic> Protecting the most vulnerable: tub…
Mariana Araújo-Pereira, Bruno B Andrade
Tuberculosis infection (TBI) affects approximately one quarter of the global population and constitutes the principal reservoir sustaining future cases of tuberculosis disease (TBD). Interferon-gamma release assays (IGRAs) have become central tools for identifying TBI, particular…