Showing 1–8 of 8 documents
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Anna Starshinova, Igor Kudryavtsev, Artem Rubinstein, Irina Dovgalyuk, Anastasia Kulpina, et al.
Tuberculosis (TB) remains a fatal disease primarily transmitted through airborne droplets, with children who are the most susceptible, particularly in the areas with poor tuberculosis control. The BCG vaccine, developed by Albert Calmette and Camille Guérin, has a history sp…
Qianfei Liu, Songnian Que, Yixuan Qiu, Mingxing Tang, Shaohua Liu, et al.
…toinfection is a key aspect of the development of effective vaccines and immunotherapies to eradicate tuberculosis. In this review, we delve into the overview of animal models of TB infection and the host's innate and adaptive immune responses toinfection. We discuss howis recogn…
Qibin Liu, Xiyong Dai, Shuang Wei
Bacille Calmette-Guérin (BCG) remains the only licensed vaccine against tuberculosis (TB), administered to >100 million neonates annually. It confers approximately 70-80% protection against tuberculous meningitis and miliary TB in early childhood, under-pinning its continued…
Kerry L Hilligan, Patricia A Darrah, Robert A Seder, Alan Sher
…jor strategy in the development of more effective BCG-based vaccines and immunotherapies.
Mariona Cortacans, Nino Gogichadze, Pablo Soldevilla, Zoran Stojanovic, Onno Akkerman, et al.
This review brings together global data on bacterial, fungal, nontuberculous mycobacterial (NTM) and viral infections that complicate the course of individuals following the diagnosis of pulmonary or extrapulmonary tuberculosis (TB). It shows how residual structural lung damage (…
Rafael Laniado-Laborín
Traditionally little attention has been paid to pediatric tuberculosis by clinicians, researchers, decision-makers, and even by national tuberculosis programs. According to the World Health Organization (WHO) Global Report for the year 2018, 10 million people developed TB in 2017…
Dhara Gosai, Jigar B. Gosai, Omprakash Shital Shukla
Background: Tuberculosis is the world's second leading cause of death from an infectious disease, being second only to AIDS. There is a lack of good data on the prevalence of all types of tuberculosis among children in India; most surveys have focused on pulmonary tuberculosis. T…
Karolina D. Witt
…s and the role of selected TB antigens in the design of new vaccines.