Showing 1–11 of 11 documents
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Sonya Krishnan, Robin Avery, Veronica Dioverti, Jeffrey A Tornheim
…. Evidence indicates that short-course, rifamycin-based TPT regimens are associated with less hepatoxicity and improved treatment completion compared to isoniazid. In the transplant population, however, drug-drug interactions limit their use, so isoniazid preventive therapy remai…
Bijan J. Ghassemieh, Masahiro Narita
…ury and a low rate of treatment completion. Rifamycin-based regimens (3 months of once weekly INH and rifapentine, 4 months of daily rifampin, and 3 months of daily INH and rifampin) are now preferred because of their effectiveness, safety, and high treatment completion rates. Pr…
Wiwat Chancharoenthana, Tanaya Siripoon, Supitcha Kamolratanakul, Viravarn Luvira, Weerapong Phumratanaprapin, et al.
…e starting preventive therapy. Short-course rifamycin-based regimens (4 months of daily rifampin [4R], 3 months of once‑weekly isoniazid plus rifapentine [3HP], or 3 months of daily isoniazid plus rifampin [3HR]) enhance completion rates compared with …
Akanksha Sirohi, Yash Vardhan Trivedi, Tavishi Katoch, Benjamin Walters, Vasu Bansal, et al.
…ased guidelines and literature on TB diagnostics, treatment regimens, and latent TB infection (LTBI) management was conducted. Key public health challenges and interventions targeting socioeconomic disparities, stigma, and healthcare access among high-risk populations were analyz…
Shahnawaz Majeed, Safiya Mehraj, Zahoor Ahmad
…DR/RR-TB)/year. This deadly TB scenario demands new TB drug regimens to tackle global infection reservoir, and worldwide spread of drug resistance and DS TB. Successful entry of single new drug into market is much complicated mission owing to time, cost, efficacy, and safety issu…
Yuqi Ma, Xiwei Lu, Xu Cao, Xintong Lv, Jiaying Li
…l, and timely drug susceptibility testing to adjust anti-TB regimens. Preventive treatment regimens for patients with diabetes and LTBI require further research. This study aims to provide evidence-based references for public health policymakers to help develop more targeted TB s…
Anna Starshinova, Ekaterina Belyaeva, Olga Irtyuga, Giunai Sefiyeva, Lubov Mitrofanova, et al.
…s the development of individualized and effective treatment regimens, which are particularly critical for pregnant patients. Recommendations for managing tuberculosis in pregnant women after COVID-19 infection include measuring D-dimer levels, performing echocardiography, and con…
Cynthia A. Bonville, Joseph B. Domachowske
…on and treatment, programs to ensure adherence to treatment regimens, and comprehensive contact tracing to identify individuals who have been exposed to active disease.
Wenzhong Hu, Yun Xu
…biomarkers, the balance of safety and efficacy in treatment regimens, and patient education to promote the optimisation of RA management strategies.
Charlotte A. Roberts, Peter Davies, Kelly E. Blevins, Anne C. Stone
…ble, drug resistance is a particular challenge in treatment regimens. In 2014 and again in 2018, the World Health Organization’s <italic>The End TB Strategy</italic> was approved by the World Health Assembly, with the goal of ending the TB epidemic by 2030 (World Health Organizat…
Katherine Timboe, J Brooks Jackson, Greta L Becker
…re focused on developing shorter, safer, and more effective regimens that incorporate both new and repurposed agents for the treatment of TB. This narrative review provides an overview of current and emerging treatment options for drug-susceptible, drug-resistant, and latent TB b…