Showing 176–200 of 200 documents
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Jyoti L Bangare, Nilofer Kittad, Sulakshana Nagpurkar
Tuberculosis (TB) remains a leading cause of illness and mortality worldwide, particularly in resource-constrained regions where timely diagnosis is critical for effective treatment. Chest computed tomography (CT) offers detailed visualization of lung structures and can reveal su…
Sapna Yadav, Syed Afzal Murtaza Rizvi
There may be a possibility of error in the manual diagnosis of tuberculosis using chest X-ray images. To effectively diagnose TB from chest X-ray images, researchers have been working hard to establish a computerized decision support system. For the healthcare industry to advance…
Komal Saxena, S Shyni Carmel Mary, Prolay Ghosh, Chinnem Rama Mohan, Mohd Naved, et al.
**BACKGROUND:** Tuberculosis (TB) is still the largest cause of death in the world, especially in countries with low and medium incomes. Multi-Drug Resistant Tuberculosis (MDR-TB), which is resistant to isoniazid and rifampicin, is a new type of tuberculosis that makes treatment …
Rahul Bhagwat Mapari, Asif Ibrahim Tamboli, Prachi Tamhan, Yogita Shelar, Sushil Bhise, et al.
**BACKGROUND:** Tuberculosis (TB) is still a major health problem around the world, especially in low- and middle-income countries, where it kills about 1.5 million people every year. Early and accurate identification is very important for treating the disease and stopping it fro…
Mahima Dwivedi
Artificial intelligence (AI) is rapidly transforming the healthcare landscape, particularly in disease prevalence and disease risk detection, and there is immense potential in India, a multi-burden health challenge. In this chapter, the use of AI-powered whole-body diagnostic dev…
Xiaoyun Du, Keqing Shi, Hao Zhang, Yingzhi Chong
Tuberculosis (TB) remains a leading global health threat, with the rise of drug-resistant (DR-TB) strains posing a significant impediment to disease control. An increasingly recognized and complex challenge is heteroresistance, the coexistence of drug-susceptible and drug-resista…
Emi Barker, Séverine Tasker
…he presentations of TB in cats Identify findings on routine diagnostics Understand the advanced diagnostics available for diagnosis of TB Feline TB: approaches to management What are the standard therapies for TB When should euthanasia be considered What are the real risks of zoo…
H Manisha Yapa, Emily L-H MacLean, Nicolas A Menzies, Peter J Dodd, Anna Dean, et al.
…bal DR-TB epidemiology and strategies for DR-TB prevention, diagnostics, and treatment. Gaps remain in DR-TB diagnosis, TB drug susceptibility testing (DST), and treatment. The review also shows that DR-TB causes significant post-disease disability, particularly chronic lung dise…
Subba Rao Cheekatla, Seong Cheol Hong, Muresan Anca Raluca, Jun-Seok Lee
…s demonstrate potential for image-guided surgery, inhalable diagnostics, and high-throughput screening of enzyme inhibitors. Together, these innovations establish a strong framework for sulfatase activity profiling and offer powerful capabilities for disease diagnostics, inhibito…
Yangyu Ou, Qi Zhang, Cheng Meng, Xingshun Zhou, Mengyao Na, et al.
Pulmonary tuberculosis (PTB) remains a major global public health challenge, with traditional diagnostic and management approaches plagued by diagnostic delays, time-consuming drug resistance testing, and subjective efficacy assessment. Artificial intelligence (AI) has emerged as…
F L Adão-Araújo, B G Ferreira, R Pontarolo, F S Tonin, S M Raboni
**OBJECTIVES:** Non-invasive methods based on exhaled breath samples have emerged as promising alternatives for the diagnosis of pulmonary tuberculosis, especially in settings where sputum collection is challenging and laboratory infrastructure is limited. We aimed to map the evi…
Lyudmila Severova, Dmitrii Giller, Inga Enilenis, Patimat Gadzhieva, Galina Shcherbakova, et al.
Pulmonary diseases caused by nontuberculous mycobacteria are increasingly becoming common worldwide and are occurring more frequently alongside pulmonary tuberculosis. Given that pulmonary diseases resulting from nontuberculous mycobacteria and pulmonary tuberculosis display simi…
Olabisi P Lawal, Fortune I Ebiala, Modinat Abayomi, Obiageri Ihuarulam Okeoma, Nana Ama Aduma Amankwah, et al.
Diabetes is increasing rapidly across Africa, where individuals in low-income areas are found to develop the disease at younger ages and lower body mass indices than those in high-income regions. Traditional metabolic risk factors explain only part of this trend, prompting growin…
G. Jignesh Chowdary, G. Suganya, M. Premalatha, K. Karunamurthy
Tuberculosis is an infectious disease that leads to the death of millions of people across the world. The mortality rate from this disease is high in patients suffering from immunocompromised disorders. early diagnosis can save lives and avoid further complications. However, the …
Parissa Farnia, Ali Akbar Velayati, Jalaledin Ghanavi, Poopak Farnia
…ing precise gene regulation studies. Advances in AI-powered diagnostics and genomic surveillance are transforming TB detection and drug resistance profiling, improving patient outcomes, especially in resource-limited settings. Overall, integrating experimental and computational i…
Haorong Chen, Sijing Liang, Wenli Li, Ting Cao, Shujun Geng, et al.
This article examines the potential of exosome analysis in diagnosing latent tuberculosis infection (LTBI). Tuberculosis (TB), caused by Mycobacterium tuberculosis, remains a significant public health challenge due to its high incidence worldwide. LTBI is a critical link in TB pr…
Rajita Bhavaraju, Bruno Andrade, Suzanne Siminski, Soyeon Kim, Mark Hatherill, et al.
…rug resistance, biomarkers, comorbidities, transcriptomics, diagnostics, and immunology. Capacity building is conducted through research fellowships and collaborations with other consortia including with a public resource database and data/specimen dashboard. **CONCLUSIONS:** Pu…
Rodrigo Santiago Moreira, César Freire de Melo Vasconcelos, Michelly Cristiny Pereira, Rafaella Ferreira das Neves, Thiago Douberin da Silva, et al.
Lung cancer is the leading cause of cancer death in both men and women and is the second most common type in both. It generally has a poor prognosis, with 75 percent of patients being diagnosed at an advanced stage. The diagnostic tools typically in use are insufficiently sensiti…
Emilee Barnard, M Maria Elgrail, Allison Fay, Yaprak Ozakman, Michael S Glickman
…rtnerships, to make meaningful progress in therapeutics and diagnostics. Altogether, we present thefield as a model for the development of a productive community that spans basic, translational, and therapeutic research, supported by public and philanthropic funding, to ultimatel…
Sudhir Kumar Mohapatra
Tuberculosis (TB) is a communal disease with high death and disease rates worldwide. The chest radiograph (CXR) is commonly used in diagnostic solutions for lung TB. Automatic computer-aided solutions to identify TB using CXRs and can advance the efficiency of the diagnostic of T…
Horia Mocanu, Adela-Ioana Mocanu
This study provides significant contributions to the understanding of tuberculosis in the field of otorhinolaryngology. It highlights the diagnostic challenges posed by the rare ENT manifestations of tuberculosis, which are often mistaken for more common conditions such as neopla…
Sonya Krishnan, Robin Avery, Veronica Dioverti, Jeffrey A Tornheim
…ls and therapeutic regimens to enhance the efficacy of LTBI diagnostics and minimize TPT side effects and drug-drug interactions in the transplant population.
Ismaheel O Lawal, Alfred O Ankrah, Sofiullah Abubakar, Honest Ndlovu, Aisha Ismaila, et al.
Tuberculosis (TB) remains a leading infectious cause of morbidity and mortality worldwide, and major diagnostic and therapeutic challenges persist despite advances in microbiologic and molecular testing. Over the past decade, molecular imaging, especially with FDG PET/CT, has tra…
Begna Tulu, Thomas Theo Brehm, Reinout van Crevel, Tobias Dallenga, Andrew R DiNardo, et al.
Tuberculosis (TB) primarily manifests as pulmonary TB (PTB), but extrapulmonary TB (EPTB) remains a major clinical challenge. Distinct diagnostic and therapeutic difficulties arise from differences in immune responses, pathogen behaviour and host susceptibility. However, the fact…
Susanna Esposito, Beatrice Rita Campana, Gaia Giorgia Arnesano, Nicola Principi
Tuberculosis (TB) remains a leading cause of morbidity and mortality worldwide, with children representing a particularly vulnerable population in whom diagnosis is often challenging. Pediatric TB is typically paucibacillary and presents with non-specific clinical manifestations,…