Showing 176–200 of 200 documents
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Kelly Urban
… popular support, he strategically expanded the state’s antituberculosis campaign, founding the National Tuberculosis Council (Consejo Nacional de Tuberculosis, or CNT) in 1936. His use of tuberculosis as statecraft constituted a key plank of his populist platform, contributed to…
Jock McCulloch, Pavla Miller
Abstract Tuberculosis became a notifiable disease in the Cape in 1907, and throughout the South African Union under the Public Health Act of 1919. The Act, which was designed to limit infection among whites, introduced programmes for early diagnosis, treatment and notification, a…
Junhui Liu, Qiusheng Jing, Zhan Lian, Chunxiang Song, Qi Zhu
…of intrabronchial lipoma in a patient with active pulmonary tuberculosis. A tumor located in the right lower bronchus was unexpectedly discovered during a bronchoscopy. Following a biopsy, the histopathological analysis confirmed it to be a lipoma. After six months of regular ant…
Do Dang Hoan, Dao Xuan Thanh, Nguyen Khac Trang, Ngô Văn Toàn
…s and prerequisites for total hip replacement in active hip tuberculosis. We carried out a quasi-experimental study. The study included 40 patients with 42 active tuberculosis hips at stage IV treated by total hip replacement from October 2016 to December 2019 at the National Lun…
Rafael Laniado-Laborín
Tuberculosis is an excellent simulator and can mimic virtually any disease. Clinically, it has been divided into primary and post-primary tuberculosis. Primary tuberculosis usually refers to patients not previously exposed to M. tuberculosis. Primary tuberculosis is more frequent…
Weibiao Han, Xuepeng Bai, Yongxiang Cheng, Chenglong Xin, Ruifeng Fan, et al.
**BACKGROUND:** Surgical treatment of thoracic spine tuberculosis using traditional procedures is often challenged by high trauma and slow recovery. This study aimed to investigate the short- and medium-term efficacy and safety of Uniportal Video-Assisted Thoracoscopic Surgery, a…
Mohd. Altaf Mir, Prince Kumar, Beena Kumari, Jaya Jain
… an overview of the diagnosis and management of soft tissue tuberculosis affecting the hand. Tuberculosis is a chronic infectious disease that can affect any part of the body, including the hand, which can lead to significant morbidity if not diagnosed and treated promptly. The c…
Dipa M. Kinariwala
…nodeficiency Virus (HIV) is the most potent risk factor for Tuberculosis progression (TB). Surveillance of HIV among & TB patients has been recognized to be important as the HIV epidemic continues to fuel TB epidemic. In those who are infected with both HIV and TB, the intera…
Peter Matuku-Kisaumbi
This chapter focuses on how biomarkers of tuberculosis can be utilized in the diagnosis, prognosis and treatment monitoring of TB. Tuberculosis biomarkers are measurable molecular indicators present and/or whose levels are altered in disease states. Found in blood, urine, broncho…
Drug-resistant tuberculosis is a re-emerging public health concern which requires special attention all around the world.Among all the infectious diseases, drug-resistant tuberculosis is now the most lethal infection causing disease in both children and adults.The co-infection of…
Joséphine Khady Badiane, Zelika Harouna Hamidou, Abdou Padane, Rita Zgheib, Hamadou Oumarou Hama, et al.
… 49 sub-Saharan African countries, which account for 85% of tuberculosis cases in Africa (WHO, 2025), to monitor the genomic dynamics of Mycobacterium tuberculosis complex strains responsible for the disease was examined for the period 2000-2025. A total of 8141 GenBank entries, …
Karthikeyan Sundaram, Leela Kagithakara Vajravelu
The association between tuberculosis and gut microbiota is notable clinical synergistic action. Tuberculosis is a highly contagious illness that poses a huge global risk., an acid-fast bacillus, is responsible for one of the top ten death associated lethal infection. The study of…
Anna Starshinova, Igor Kudryavtsev, Artem Rubinstein, Irina Dovgalyuk, Anastasia Kulpina, et al.
Tuberculosis (TB) remains a fatal disease primarily transmitted through airborne droplets, with children who are the most susceptible, particularly in the areas with poor tuberculosis control. The BCG vaccine, developed by Albert Calmette and Camille Guérin, has a history sp…
Margarida Saraiva, William J Branchett, Jyothi Rengarajan, Anne O'Garra
Tuberculosis (TB) remains a global health issue and leading cause of death. Understanding the immune response to Mycobacterium tuberculosis infection is critical to advance TB control. Although immune factors involved in protection against TB have long been identified, these cann…
Huicong Liu, Haoran Li, Shanshan Li, Yuanyuan Shang, Shenjie Tang, et al.
Tuberculosis (TB) is a chronic infectious disease caused by(). Despite significant advancements in anti-tuberculosis treatment strategies in recent years, TB remains a major infectious disease threat worldwide. Chronicinfection drives T cell exhaustion-characterized by upregulate…
Mohini Agrawal, K Shyamsundar, Keerthana Raghu, Rajiv Raman, L Dhanurekha, et al.
**BACKGROUND:** Intraocular tuberculosis (OTb) is a sight-threatening manifestation of Mycobaterium tuberculosis infection. It is characterized by a wide spectrum of clinical phenotypes, including anterior uveitis, posterior uveitis, retinal vasculitis, and choroiditis. Diagnosis…
Ruchi Nair, Pooja Thakur, Hitesh D. Patel
Tuberculosis (TB) management and the prevention of drug-resistant strains rely heavily on timely detection and efficient treatment. Conventional diagnostic methods, while accurate, frequently require expensive laboratory equipment and can take several weeks, emphasizing the criti…
Maria-Cristina I Loader, Deborah L W Chong, Keira H Skolimowska, Jon S Friedland
…the interface of inflammation, tissue injury, and repair in tuberculosis. In pulmonary tuberculosis, dysregulated MMP activity drives extracellular matrix degradation, cavitation, and remodelling that contribute to post-tuberculosis lung disease. In tuberculous meningitis, MMPs h…
Onix Cantres-Fonseca
Mycobacterium tuberculosis is one of the most pathogenic infectious organisms, usually known for causing cavitary lung infection. But this mycobacterium is also capable of causing masked involvement in any organ of the body. Its clinical manifestation can mimic other conditions a…
Mohit Bhagchandani, Praveen Kumar Arya, Shashank Nigam, Sandeep Verma
… us with sub-acute intestinal obstruction due to intestinal tuberculosis. Tuberculosis infection has a high incidence in the immunocompromised individual or patients with pre-existing illness or undergoing any immunosuppression. Although many cases of abdominal tuberculosis are f…
Benson Olu Akinshipe, Anthony Chukwuka Nwaobi, Emmanuel Babatunde Adedeji, Friday Alfred Ehiaghe, Herbert Obi Okpala
Host immune response against Mycobacterium tuberculosis (MTb) is mediated by cellular immunity in which cytokines and MTb-specific T cells play an important role. The detection of MTb and discrimination between different states of MTb infection is possible by immunodiagnostic tes…
Tao Shi, Tongxin Li, Xuewu Xing
Extra-pulmonary Mycobacterium tuberculosis (EPTB) is a threat and challenge to human health that affects bone, urinary, skin, soft tissues, and lymph nodes. EPTB always comes from pulmonary tuberculosis (PTB), while there are some patients who have never had any PTB symptoms or (…
Şule Kızıltaş, Aylin Babalık
…er COVID-19 [1]. TB is caused by the bacillus Mycobacterium tuberculosis which is spread from one person to another through the air. M. tuberculosis is estimated to infect approximately one-fourth of the world’s population [2, 3]. According to the World Health Organization (WHO) …
Rosella Centis, Lia D'Ambrosio, Giovanni Battista Migliori
Tuberculosis is an airborne infectious disease treated with combination therapeutic regimens. Adherence to long-term antituberculosis therapy is crucial to maintain adequate blood drug level. The emergence and spread of drug-resistantstrains is mainly favored by the inadequate me…
Rodolfo L Chávez-Domínguez, Martha Torres, Atziri A Acevedo-Domínguez, Jesús A Ibarra-Inocente, Claudia Carranza
Pulmonary tuberculosis, caused by(Mtb), remains one of the leading causes of infectious disease-related mortality worldwide. In parallel, lung cancer represents the most lethal neoplasm, with high mortality rates globally. Emerging studies suggest that chronic Mtb infection may c…