Showing 126–150 of 200 documents
Sorted by hybrid relevance (keyword + semantic via RRF)
Kaviyashruthi Thamilselvi Senthivel, Tatineni Saiteja, Beaulah Jeyavathana, M. Uma
…rognosis. This study responds to the urgent needs of better diagnostics for tuberculosis while edging global health concern.
Sandeep Rai, Abhishek Sen, Harsh Shah, Jay Patel
…tem included insufficient drug resistance testing, delay in diagnostics, a lack of healthcare personnel, inadequate referral chains, and inconsistent treatment regimens. Lack of streamlined referral pathways and non-standardised treatment regimens posed problematic operational ch…
Prakruthi Shivakumar, Kavitha Sunil Shettigar
Tuberculosis (TB) is caused by a single infectious agent, Mycobacterium tuberculosis, and a public health concern due to increased cases of drug-resistance and high mortality rates. Rapid identification of tuberculosis is necessary for its early treatment and to prevent the emerg…
Andrea Rubini, Roberto Di Via, Vito Paolo Pastore, Francesca Del Signore, Martina Rosto, et al.
…medicine. Both fields demonstrate AI's potential to enhance diagnostics but emphasize the ongoing need for human expertise in clinical decision making. Differences in anatomy structure between the two fields must be considered for effective AI adaptation.
Riccardo Inchingolo, Lorenzo Carriera, Simone Ielo, Roberto Barone, Andrea Smargiassi, et al.
Tuberculous pleural effusion (TPE) is currently the most common form of extrapulmonary tuberculosis and remains a significant cause of pleural disease worldwide, particularly in endemic regions. It often presents with non-specific clinical symptoms, such as fever, chest pain, cou…
Yang Cui, Haoran Li, Tianhui Liu, Rujie Zhong, Jiaying Guo, et al.
Tuberculosis (TB) remains a formidable global public health challenge. The rising prevalence of drug-resistant TB and increased human immunodeficiency virus(HIV) co-infection further exacerbate TB control efforts. Mycobacterium tuberculosis (Mtb) achieves highly heterogeneous inf…
Aigul Utegenova, Lazzat Kassayeva, Bayan Turdalina, Aliya Baiduissenova, Ayaz Yktiyarov, et al.
Latent tuberculosis infection (LTBI) represents a major global health concern as it constitutes the principal reservoir for future tuberculosis (TB) disease. Its identification is particularly important in Bacille Calmette-Guérin (BCG)-vaccinated populations, where cross-rea…
Gamze Tanriver, Salman Ali Khan, Artur Góra, Novel N Chegou, Shima Mahmoudi
Tuberculosis (TB) remains a significant global health challenge, necessitating continued research efforts to unravel its complex pathogenesis and advance diagnostic, therapeutic, and preventive strategies. Resuscitation-promoting factors (Rpfs) are peptidoglycan-hydrolyzing enzym…
Mohammad Hassan Sadeghi, Safa Radmehr, Neda Mohagheghzadeh, Javad Fathi, Yalda Malekzadegan, et al.
…ble potential of electrochemical biosensors to transform TB diagnostics, ultimately assisting in better disease management and control strategies worldwide.
Saurav Jyoti Patgiri, Anukalpa Saikia, Sushmita Yadav, Md Atique Ahmed, Luna Adhikari, et al.
**BACKGROUND:** Melioidosis, caused by, is a severe and often underdiagnosed infection endemic to South Asia, Southeast Asia, and northern Australia. While pneumonia and sepsis are the classical presentations, the disease is increasingly recognized for its diverse and atypical cl…
Sameeullah Memon, Shabana Bibi, Guozhong He
Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis. Despite the improvements in diagnostic techniques, the accuracy of TB diagnosis is still low. In recent years, the development of artificial intelligence (AI) has opened up new possibilities in diagn…
Lu Lu Zhang, Jun Ping Peng
Tuberculosis (TB) continues to pose a significant threat to global public health, necessitating rapid and precise diagnostic methods and comprehensive detection of antimicrobial resistance (AMR) to facilitate timely clinical management. Traditional diagnostic techniques suffer fr…
Yingxiao Han, Songwei Ma, Rui Ma, Jingjing Li, Lei Qiu, et al.
…roteomics, and serological validation advances TB precision diagnostics.
Takahiro Takazono, Masato Tashiro, Koichi Izumikawa, Hiroshi Mukae
Chronic pulmonary aspergillosis (CPA) is a refractory infectious disease that occurs in patients with mildly compromised immunity or an underlying pulmonary disease. The mortality rate associated with pulmonary aspergillosis has also increased. In the diagnosis and management of …
Thomas Hänscheid, Sara Mahomed, Laila Oliveira, Danielle Segóvia Pereira, Martin P Grobusch
Acid-fast stains (AFS) remain indispensable in modern diagnostic microbiology; they are used for detecting mycobacteria (including Mycobacterium tuberculosis and Mycobacterium leprae), acid-fast parasites, and some acid-variable bacteria as well as in histopathology. Fluorescent …
Leeberk Raja Inbaraj, Mukesh Kumar Sathya Narayanan, Priya Rajendran, Bella Devaleenal Daniel, Sivakumar Shanmugam, et al.
**INTRODUCTION:** Early diagnosis and treatment initiation are essential to prevent ongoing tuberculosis (TB) transmission and reduce the disease burden. Smear microscopy, which is widely used test for diagnosis, has limited sensitivity and does not detect rifampicin resistance. …
Nuttapon Jirakittiwut, Panan Ratthawongjirakul
**BACKGROUND:** Detecting tuberculosis (TB) remains challenging in low-resource settings due to limited access to advanced diagnostic tools. The emergence of isothermal amplification techniques, such as loop-mediated isothermal amplification (LAMP), presents a promising solution …
Promod K Mehta, Jefry Sebastian
…ance in resource-limited settings. To overcome this, Molbio Diagnostics, India, introduced a Truenat/TruPlus assay (the WHO endorsed), which is chip-based micro real-time PCR system that targets nrdB, while TruPlus targets IS6110+nrdZ for the identification of Mtb within 1 h…
Nin-Chieh Hsu, Yu-Feng Lin, Hung-Bin Tsai, Charles Liao, Chia-Hao Hsu
…this, PoCUS should be applied in parallel with conventional diagnostics and integrated into comprehensive clinical assessment. Standardized training, multi-zone scanning protocols, and structured image acquisition are recommended to improve reproducibility and inter-operator cons…
Salma Madihi, Achraf Aainouss, Mly Driss Ei Messaoudi, Abdelouaheb Benani
Tuberculosis (TB) is a major health burden, the leading cause of death among people living with HIV, and one of the main causes of death linked to antimicrobial resistance. The World Health Organization (WHO) launched in 2015 the End TB Initiative that aims to reduce TB cases and…
Xinxin Fan, Muxing Chen, Di Wu, Youfei Lin, Xiaohong Chen
According to the 2024 World Health Organization (WHO)Global Tuberculosis (TB)Report, tuberculosis remains the leading cause of death from a single infectious agent, with 10.8 million new cases and 1.25 million deaths in 2023. Early and standardized treatment upon definitive diagn…
Kenneth W Foreman, Hui-Chen Foreman
…a broadly effective vaccine, limited sensitivity of current diagnostics, particularly for paucibacillary and extrapulmonary TB, and significant adverse effects associated with prolonged small-molecule drug regimens. The growing prevalence of multidrug-resistant (MDR) and extensiv…
Mehdi Roshdi Maleki, Seyyed Reza Moaddab
Nontuberculous mycobacteria (NTM) are emerging pathogens responsible for a growing spectrum of diseases, particularly in individuals with underlying lung disorders or immune suppression. Once considered primarily environmental saprophytes, NTM are now recognized as important caus…
Søren Saxmose Nielsen
<title>Abstract</title> This chapter discusses immune-based diagnostics for various testing and decision making purposes for <italic>Mycobacterium avium</italic> subsp. <italic>paratuberculosis</italic> and outlines the diagnostic process.
Ashish Ranjan, Ajantha Panneerselvam, Saroj Meena, Rajnish Gupta
…nd treatment. Advances in rapid molecular and culture-based diagnostics have improved TB detection in silicosis patients. TB treatment is done as per National Tuberculosis Elimination Programme (NTEP) Guidelines and TB preventive treatment (TPT) given to silicotic patients after …