Showing 101–125 of 200 documents
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Supriya Mallick, Manish Shankar, Satyadeo Choubey, Arshad Ejazi, Rakesh Kumar, et al.
**BACKGROUND:** Multidrug-resistant tuberculosis continues to be a major threat to mankind and is a major social and economic burden to society. Line probe assay (LPA) is a method for detecting Mycobacterium tuberculosis (MTb) in combination with resistance to rifampicin and ison…
Cara Adolph, Simon C Mendelsohn, Laura E Via, Leonardo Martinez, Cecilia S Lindestam Arlehamn, et al.
Tuberculosis remains a leading cause of death, underscoring the urgent need for a new vaccine. Progress in vaccine development is hampered by incomplete understanding of how Mycobacterium tuberculosis causes infection and disease, and of protective immunity following natural infe…
Cara Adolph, Simon C Mendelsohn, Laura E Via, Leonardo Martinez, Cecilia S Lindestam Arlehamn, et al.
Progress in tuberculosis vaccine development is hindered by the incomplete understanding of protective immunity and other disease mechanisms. An interconnected network of sample biorepositories from tuberculosis studies could help to address these gaps. To assess the feasibility …
Dinesh Kumar Sharma
Since the early centuries until the present, tuberculosis has been a global illness with no cure. However, the sickness remains dormant in the afflicted individuals in certain circumstances. Due to the thick lipid mycobacterial wall and the challenging medication delivery into th…
Etang UE, Richard RE, Nseobong Godwin Akpan, Emily Vu, Ntekpere EI, et al.
Tuberculosis remains a leading cause of mortality, especially in countries with low socio-economic status. Socio-economic determinants influence individuals’ health behaviours, access to healthcare resources, degree of exposure to certain diseases and environmental factors. The i…
Jason R Andrews, Salome Charalambous, Gavin Churchyard, Frank Cobelens, Carlos Fernández-Escobar, et al.
…are among the populations experiencing the highest rates of tuberculosis. Prisons typically create ideal conditions for Mycobacterium tuberculosis transmission, including overcrowding and prolonged exposure in poorly ventilated environments, and often have populations at high ris…
Alicia M Gutiérrez-Mauricio, Juan Valentín Trujillo-Paez, Luis Alberto Trejo-Martinez, Bruno Rivas-Santiago, Paola Pérez-García, et al.
Tuberculosis (TB) is a contagious infectious disease caused by the bacillus Mycobacterium tuberculosis (Mtb). It is transmitted through small particles in the air (<5 µm) expelled by active tuberculosis patients; when inhaled by a new host, they can potentially cause …
Roshna Lytton, Nanda Kumar Paniyadi, Prasanta Raghab Mohapatra, Priyanka Singh, Anuradha Kumari, et al.
**INTRODUCTION:** Individuals diagnosed with tuberculosis often experience concerns regarding potential social isolation affecting their family life, education, marriage, occupation, treatment, and social life. The goal of the present study was to determine the prevalence of stig…
W. Henry Boom
M. tuberculosis remains one of the most successful human pathogens. The ability of M. tuberculosis to elicit vigorous acquired immune responses and use of the macrophage as primary cell to infect, suggest that the organism has evolved multiple strategies to survive and persist in…
Onix Cantres-Fonseca, Francisco Del Olmo-Arroyo
…itiated in 2019 makes possible to forget other causalities. Tuberculosis makes the case. The pathogen has been present more than hundredth years. Relevance rest in worldwide prevalence, pathogen spread, treatment resistance and the need for eradication. Drug treatment resistance …
Anjali Dhote, Vikas Kawishwar
Tuberculosis is one of humanity's oldest diseases, as well as one of the deadliest epidemics. Mycobacterium tuberculosis infects one-third of the world's population, with 9.6 million new cases reported each year. Tuberculosis kills almost 1.45 million people per year, making it t…
Xue‐Song Xiong, Qin Zhu, Zhan-Zhong Liu, Ting-Ting Huang, Jin-Bin Fan, et al.
…thogens in the genus Mycobacterium, including Mycobacterium tuberculosis (MTB) complex, nontuberculous mycobacteria (NTM), and Mycobacterium leprae. Tuberculosis caused by M. tuberculosis has become the leading cause of death of a single infectious disease after novel coronavirus…
Namgyal dolma, Smriti Sharma
This chapter significantly defines Tuberculosis (TB) as an infectious disease caused by mycobacterium tuberculosis bacillus. M. Tuberculosis is rod-like in shape, highly aerobic and it requires high levels of oxygen. It’s a serious illness which mainly affects the mammalian respi…
Mingyang Hong, Xu Huang, Huiming Zhu, Jiahui Ma, Feng Li
…gained significant attention in recent years, especially in tuberculosis research. Tuberculosis poses a major global public health threat. Its complex pathological mechanisms and worsening drug resistance urgently necessitate new research breakthroughs. The role of circRNA in myc…
Saurov Mahanta, Bhaskarjyoti Gogoi, Tanti Bhaben
Tuberculosis is the disease which is caused due to the infection of Mycobacterium tuberculosis. The multidrug resistance Mycobacterium tuberculosis is the main problem in the treatment of this worldwide health threats. So there is an urgent need for the development of new drug fo…
Anca Ionela Fâcă, Denisa Ioana Udeanu, Andreea Letiția Arsene, Beatrice Mahler, Doina Drăgănescu, et al.
Tuberculosis is an infectious condition caused by, primarily targeting the pulmonary system, with the potential to disseminate to various other organs via the haematogenous pathway, ranking among the top ten causes of global mortality. Tuberculosis remains a serious public health…
Akshay Girish Manikoth, Manoj Kumar Bisht, Sudip Ghosh, Sangita Mukhopadhyay
Tuberculosis is an infectious disease primarily caused by the bacterium Mycobacterium tuberculosis. This bacterium infects about 10 million and kills about 1.6 million people annually. M. tuberculosis infects macrophages and manipulates its defense functions …
Lucas Gabriel Quadros Ramos, Fernanda Moreira Soares Boaventura Silveira, Jessica Elen Martins Alves, Karina Andrade de Prince
Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis, considering that this comorbidity represents a public health problem, it is of paramount importance to understand the associated clinical, epidemiological, and economic factors due to its high prevalence …
Meiru Chen, Yating Wang, Dongqiang Zhao
**BACKGROUND:** Hepatic hilar tuberculosis lymphadenitis is a rare condition that often mimics other diseases, leading to diagnostic challenges due to its nonspecific clinical presentation. It can be easily mistaken for a malignant tumor, complicating the diagnostic process. **C…
Dilvani Oliveira Santos, Paulo R. Z. Antas
Tuberculosis (TB) is a contagious infectious disease that is a major cause of morbidity, being one of the top 10 causes of death worldwide, and the leading one from a single infectious agent. Also called “White Plague” in the past, TB is an airborne disease, propagated when multi…
Simone Villa, Giovanni Battista Migliori, Lia D’Ambrosio, Mario Raviǵlione
Tuberculosis is an infectious disease caused by bacteria of the Mycobacterium tuberculosis complex that are transmitted through air droplets from persons with pulmonary tuberculosis. Once exposed, a person might become infected but only 5–10% of them will, eventually, develop the…
Wida Purbaningsih, Sadeli Masria, Yani Triyani, Maya Tejasari
Diagnosing extrapulmonary tuberculosis remains difficult because not all medical care facilities can do it as the microbiological examination of tissue materials requires invasive action and special equipment. Extrapulmonary tuberculosis diagnosis should be made by observing clin…
Jamilah Meghji, Sara C Auld, Gregory P Bisson, Celso Khosa, Refiloe Masekela, et al.
…scribing the high burden of respiratory sequelae seen among tuberculosis survivors, including children, adolescents, and adults. This group of sequelae are known as post-tuberculosis lung disease and include parenchymal damage, airway disease, and pulmonary vascular disease. It i…
Gagan Chooramani, Pooja Singh
…e World Health Organization has declared that the spread of tuberculosis is a global emergency. Despite the implementation of strong tuberculosis-control initiatives by WHO, this highly infectious disease continues to affect all vulnerable populations, including the elderly popul…
Abhishek Yadav, C.P. Baveja, Tanisha Bharara, Vasim Ahmad
Tuberculosis causes morbidity in millions of people per year and is one of the top 10 causes of mortality worldwide. Though pulmonary TB is the commonest form, extra–pulmonary Tuberculosis (EPTB) carries its fair share of morbidity and mortality. The various extra–pulmonary sites…