Showing 51–75 of 200 documents
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Gwen A. Huitt
…been used to describe the process by which individuals with tuberculosis undergo a transformation from robust, healthy individuals, into frail and emaciated shadows of themselves. There are many factors that contribute to the catabolic state and malnutrition in patients with tube…
Richard M. Hodes, Mogues Azbite
Tuberculosis is one of the most serious health problems in developing countries, causing almost 7% of all deaths in 1990. Tuberculosis may contribute significantly to protein malnutrition, especially in those with borderline nutritional status due to increased protein catabolism …
Ishola Dada Muraina, Rafeeah Rufai Madaki, Aisha Umar Suleiman
… drastic attention toward its eradication across the world. Tuberculosis as one of infectious diseases in Nigeria needs urgent measures so as to achieve a healthy society. Despite the huge fund spends on the eradication of tuberculosis in Nigeria, its awareness status is yet to b…
François Willermain, Laure Caspers, Weber Celia, Dorine Makhoul
Uveitis is reported to be related to tuberculosis in 0.2–20% of cases. This large range reflects prevalence variations of tuberculosis around the globe as well as differences in diagnostic criteria. In addition, patients with noninfectious uveitis are frequently treated by immuno…
Jinsoo Min, Bruno B Andrade, Ju Sang Kim, Yoolwon Jeong
Recent advancements in tuberculosis treatment research emphasize innovative strategies that enhance treatment efficacy, reduce adverse effects, and adhere to patient-centered care principles. As tuberculosis remains a significant global health challenge, integrating new and repur…
Xingyu Lu, Yiyi Hu, Yue Hu, Fei Zhao, Peiyang Fan, et al.
Tuberculosis (TB) is a serious disease that poses a significant threat to the health of children and adolescents, with(PTB) being the most common type. Due to the lack of specificity in clinical manifestations and symptoms, early screening and diagnosis of pediatric pulmonary tub…
Onesime Mbulayi, Saint-Jean Djungu, Loukia Aketi, Mohammed Amine Koulali, Hanae Azzaoui, et al.
Tuberculosis, an infectious disease caused by, poses a major global health challenge. Despite being largely controlled for several decades, tuberculosis has experienced a resurgence in recent years. China has the second highest incidence of tuberculosis globally, with a prevalenc…
Jason R Andrews, Salome Charalambous, Gavin Churchyard, Frank Cobelens, Carlos Fernández-Escobar, et al.
…are among the populations experiencing the highest rates of tuberculosis. Prisons typically create ideal conditions for Mycobacterium tuberculosis transmission, including overcrowding and prolonged exposure in poorly ventilated environments, and often have populations at high ris…
Dinesh Kumar Sharma
Since the early centuries until the present, tuberculosis has been a global illness with no cure. However, the sickness remains dormant in the afflicted individuals in certain circumstances. Due to the thick lipid mycobacterial wall and the challenging medication delivery into th…
Etang UE, Richard RE, Nseobong Godwin Akpan, Emily Vu, Ntekpere EI, et al.
Tuberculosis remains a leading cause of mortality, especially in countries with low socio-economic status. Socio-economic determinants influence individuals’ health behaviours, access to healthcare resources, degree of exposure to certain diseases and environmental factors. The i…
Roshna Lytton, Nanda Kumar Paniyadi, Prasanta Raghab Mohapatra, Priyanka Singh, Anuradha Kumari, et al.
**INTRODUCTION:** Individuals diagnosed with tuberculosis often experience concerns regarding potential social isolation affecting their family life, education, marriage, occupation, treatment, and social life. The goal of the present study was to determine the prevalence of stig…
Cara Adolph, Simon C Mendelsohn, Laura E Via, Leonardo Martinez, Cecilia S Lindestam Arlehamn, et al.
Progress in tuberculosis vaccine development is hindered by the incomplete understanding of protective immunity and other disease mechanisms. An interconnected network of sample biorepositories from tuberculosis studies could help to address these gaps. To assess the feasibility …
Cara Adolph, Simon C Mendelsohn, Laura E Via, Leonardo Martinez, Cecilia S Lindestam Arlehamn, et al.
Tuberculosis remains a leading cause of death, underscoring the urgent need for a new vaccine. Progress in vaccine development is hampered by incomplete understanding of how Mycobacterium tuberculosis causes infection and disease, and of protective immunity following natural infe…
Meiru Chen, Yating Wang, Dongqiang Zhao
**BACKGROUND:** Hepatic hilar tuberculosis lymphadenitis is a rare condition that often mimics other diseases, leading to diagnostic challenges due to its nonspecific clinical presentation. It can be easily mistaken for a malignant tumor, complicating the diagnostic process. **C…
Mingyang Hong, Xu Huang, Huiming Zhu, Jiahui Ma, Feng Li
…gained significant attention in recent years, especially in tuberculosis research. Tuberculosis poses a major global public health threat. Its complex pathological mechanisms and worsening drug resistance urgently necessitate new research breakthroughs. The role of circRNA in myc…
Lucas Gabriel Quadros Ramos, Fernanda Moreira Soares Boaventura Silveira, Jessica Elen Martins Alves, Karina Andrade de Prince
Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis, considering that this comorbidity represents a public health problem, it is of paramount importance to understand the associated clinical, epidemiological, and economic factors due to its high prevalence …
Akshay Girish Manikoth, Manoj Kumar Bisht, Sudip Ghosh, Sangita Mukhopadhyay
Tuberculosis is an infectious disease primarily caused by the bacterium Mycobacterium tuberculosis. This bacterium infects about 10 million and kills about 1.6 million people annually. M. tuberculosis infects macrophages and manipulates its defense functions …
W. Henry Boom
M. tuberculosis remains one of the most successful human pathogens. The ability of M. tuberculosis to elicit vigorous acquired immune responses and use of the macrophage as primary cell to infect, suggest that the organism has evolved multiple strategies to survive and persist in…
Onix Cantres-Fonseca, Francisco Del Olmo-Arroyo
…itiated in 2019 makes possible to forget other causalities. Tuberculosis makes the case. The pathogen has been present more than hundredth years. Relevance rest in worldwide prevalence, pathogen spread, treatment resistance and the need for eradication. Drug treatment resistance …
Anjali Dhote, Vikas Kawishwar
Tuberculosis is one of humanity's oldest diseases, as well as one of the deadliest epidemics. Mycobacterium tuberculosis infects one-third of the world's population, with 9.6 million new cases reported each year. Tuberculosis kills almost 1.45 million people per year, making it t…
Saurov Mahanta, Bhaskarjyoti Gogoi, Tanti Bhaben
Tuberculosis is the disease which is caused due to the infection of Mycobacterium tuberculosis. The multidrug resistance Mycobacterium tuberculosis is the main problem in the treatment of this worldwide health threats. So there is an urgent need for the development of new drug fo…
Francisco de Assis Moura Batista, Juliana Iscarlaty Freire de Araújo, Fernanda Cunha Soares, Thalyta Cristina Mansano Schlosser, Clarissa Terenzi Seixas, et al.
Tuberculosis is an infectious disease with a substantial impact on public health, with the pulmonary form representing the most significant concern. The disease poses considerable risks to the elderly population, as it frequently manifests in conjunction with other age-related co…
Abhishek Yadav, C.P. Baveja, Tanisha Bharara, Vasim Ahmad
Tuberculosis causes morbidity in millions of people per year and is one of the top 10 causes of mortality worldwide. Though pulmonary TB is the commonest form, extra–pulmonary Tuberculosis (EPTB) carries its fair share of morbidity and mortality. The various extra–pulmonary sites…
Daniel Peptenatu, Aurel Mihail Băloi, Octavian Andronic, Andreea Karina Gruia, Alexandra Grecu, et al.
…singly recognized globally, and infectious diseases such as tuberculosis are significantly influenced by the quality of the environment. The research examines the correlation between contamination of the environment and the elevated prevalence of tuberculosis in Romania, one of t…
Evelina Lesnic, Alina Malic, Adriana Niguleanu, Tatiana Osipov
According to the actual national policy, the patients with tuberculosis may benefit from the following anti-tuberculosis treatment options: a) directly observed delivered in the community close to the patient’s home or work; b) treatment provided in hospitals or specialized dispe…