Showing 51–75 of 200 documents
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Lindsay H. Cameron, Jeffrey R. Starke
Childhood tuberculosis differs from adult tuberculosis in epidemiology, clinical and radiographic presentation, and treatment. The risk of a child developing tuberculosis is influenced by age, immune status, and the intensity of exposure to a source case with tuberculosis disease…
Richard Wismayer
Introduction: Tuberculosis remains a global public health concern. Abdominal tuberculosis is an atypical presentation and since it is extrapulmonary it may delay the diagnosis and treatment of this condition. The mortality associated with treated abdominal tuberculosis is 15% des…
Gregory P Bisson, Brian Allwood, Anthony Byrne, Gunar Günther, Celso Khosa, et al.
… substantial burden of long-term pulmonary impairment among tuberculosis survivors, marked variability in how post-tuberculosis lung disease is defined across research studies limits the comparison of findings and synthesis of evidence. To facilitate greater harmonisation within …
Shivprasad Kasat, Mahendra Biradar, Ashish Deshmukh, Sunil Jadhav, Hafiz Deshmukh
…d reliability of CBNAAT in the diagnosis of extra pulmonary tuberculosis (EPTB) cases in comparison to AFB smear. Tuberculosis is still a major public health issue around the world. Mycobacterium tuberculosis is thought to infect one-third of the world's population. The two types…
Rajeev Ranjan, Venkata Siva Reddy Devireddy
Drug resistant tuberculosis is a major public health concern, since the causative agent Mycobacterium tuberculosis is resistant to the most effective drugs against tuberculosis treatment ie., rifampicin and isoniazid. Globally, it accounts 4.6 percent of the patients with tubercu…
Dhara Gosai, Jigar B. Gosai, Omprakash Shital Shukla
Background: Tuberculosis is the world's second leading cause of death from an infectious disease, being second only to AIDS. There is a lack of good data on the prevalence of all types of tuberculosis among children in India; most surveys have focused on pulmonary tuberculosis. T…
Nuttapon Jirakittiwut, Panan Ratthawongjirakul
**BACKGROUND:** Detecting tuberculosis (TB) remains challenging in low-resource settings due to limited access to advanced diagnostic tools. The emergence of isothermal amplification techniques, such as loop-mediated isothermal amplification (LAMP), presents a promising solution …
Timothy M Walker, James A Watson, David A J Moore, Mike Frick, Euzebiusz Jamrozik
Preventive therapy remains key to the elimination of tuberculosis and is typically offered to people with presumptive Mycobacterium tuberculosis infection to prevent active disease. Although the duration of tuberculosis preventive therapy has been reduced substantially over time,…
Horia Mocanu, Adela-Ioana Mocanu
… provides significant contributions to the understanding of tuberculosis in the field of otorhinolaryngology. It highlights the diagnostic challenges posed by the rare ENT manifestations of tuberculosis, which are often mistaken for more common conditions such as neoplasms or chr…
Matthew J Saunders, Delia Boccia, Palwasha Y Khan, Lara Goscé, Antonio Gasparrini, et al.
… is likely to exacerbate a range of determinants that drive tuberculosis, the world's leading cause of death from a single infectious agent. However, tuberculosis is often neglected in wider climate health discussions. Commissioned by WHO, we developed an analytical framework out…
Sriram Krishnamoorthy, Kalpana Ramachandran
…caused a severe dent in the decades of progress achieved in tuberculosis control and elimination measures, indicating that these measures need to be more structured and resilient. This manuscript focuses on the impact of the COVID-19 pandemic on TB control and also on the measure…
Stacie Burke
…ammation is the immune system's natural response to initial tuberculosis infection. Tuberculosis bacteria have gained adaptations to manipulate the inflammatory process, sometimes settling into latency and containment in granulomas, ensuring their survival. Grounded in an evoluti…
Dan Ye, Ning Gan, Yang Yang, Zhentao Fei, Huarui Liu, et al.
**BACKGROUND:** To examine the clinical features of adrenal tuberculosis to improve clinicians' diagnostic accuracy and treatment strategies. **METHODS:** We report on nine patients diagnosed with adrenal tuberculosis at the Shanghai Public Health Clinical Center between January…
Qiuyue Song, Junlin Liu, Chunhua Wang
Tuberculosis is a severe infectious disease caused by(MTB) infection and poses a serious public health challenge globally. The prevalence of multidrug-resistant MTB in countries with a high burden of tuberculosis has further increased the challenges of tuberculosis prevention and…
Amira Mahmood, Mohammad Bilal Ashfaq, Catherine Drain, Eoin Melby, Michael Hunter, et al.
Tuberculosis remains the biggest global killer from infectious causes, with an estimated 1.25 million deaths per year. The quadruple drug regimen of rifampicin, isoniazid, pyrazinamide, and ethambutol has been standard therapy for 40 years, with good outcomes in patients with dru…
Tyler S Brown, Kristin Nelson, Stephen Kissler, Leo Martinez, C Robert Horsburgh, et al.
Tuberculosis remains a persistent threat to global public health. Ultimately, future progress towards tuberculosis elimination is contingent on our ability to interrupt Mycobacterium tuberculosis transmission between individuals who are infectious and their susceptible contacts. …
Archana Shrivastava
The aim of study is to evaluate early diagnosis of tuberculosis with simple and easy technique and to study in occurrence at various extra pulmonary sites. In our country, tuberculosis is the most common and serious infectious cause of death. Tuberculosis can affect any organ sys…
Sandy B. Primrose
The principal diseases caused by mycobacteria are tuberculosis and leprosy. Descriptions of both diseases can be found in pre-Christian Greek literature and DNA from both has been recovered from ancient skeletons. Leprosy is caused by <italic>Mycobacterium leprae</italic> and <it…
Karthikeyan Sundaram, Sathyapriya Subramani, Venkataraman Prabhu
Mycobacterium tuberculosis (MTB) causes Tuberculosis (TB), which is a fatal infectious disease. Timely diagnosis of tuberculosis is crucial, and the conventional culture method is time-consuming and smear microscopic staining is less sensitive. Significantly, rapid molecular diag…
Vikash Gupta, Rajeev Tandon, Vijeta Niranjan, Ankit Kumar
… bacilli (AFB) in sputum samples is essential for pulmonary tuberculosis diagnosis. Sputum production may be absent in 40-60% of patients with probable pulmonary tuberculosis. Identification of active pulmonary tuberculosis disease patients is an important component of TB control…
Yinfeng Su, Xingxing Kong, Zhanpeng Chen, Xiaomin Wang, Shuihua Lu
Tuberculosis in pregnancy is a series of diseases caused by(). Exact global incidence rates are difficult to obtain and are expected to be similar to those in the general population, with potentially higher rates in developing countries. Tuberculosis in pregnancy is associated wi…
Jalaledin Ghanavi, Poopak Farnia
Tuberculosis and its pathogen, Mycobacterium tuberculosis complex, are a major health challenge. The causative agent of tuberculosis is M. tuberculosis complex and is transmitted through airborne droplets. Tumor necrosis factor-alpha (TNF-α) is one of the cytokines that med…
M. Rajeswari, Riley Malar, Raheem Unissa, Pechetti Sujjani
Mycobacterium tuberculosis is the bacteria that causes tuberculosis (TB), a communicable disease that mostly affects the lungs but can also affect other regions of body. The World Health Organization (WHO) forecasts that approximately 10 million individuals worldwide contracted t…
Phool Chandra, Prashant Kumar, Surya Nath Pandey, Manoj Kumar Bisht
Tuberculosis (TB), developed by the Gram-positive bacterium Mycobacterium tuberculosis, is the prominent cause of demise globally due to high antibiotic resistance. Approximately 1.5 million people deceased of TB in 2020 worldwide. The causative pathogen of tuberculosis spreads m…
Murat Kılıç
Tuberculosis (TB) is the most common infectious disease that will cause death worldwide by 2022, apart from Covid-19. More than 10 million people are infected each year, and half of untreated cases can be fatal. TB usually affects the lungs and is transmitted through the air. Ext…