Showing 26–50 of 200 documents
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Gregory P Bisson, Brian Allwood, Anthony Byrne, Gunar Günther, Celso Khosa, et al.
… substantial burden of long-term pulmonary impairment among tuberculosis survivors, marked variability in how post-tuberculosis lung disease is defined across research studies limits the comparison of findings and synthesis of evidence. To facilitate greater harmonisation within …
Nuttapon Jirakittiwut, Panan Ratthawongjirakul
**BACKGROUND:** Detecting tuberculosis (TB) remains challenging in low-resource settings due to limited access to advanced diagnostic tools. The emergence of isothermal amplification techniques, such as loop-mediated isothermal amplification (LAMP), presents a promising solution …
Timothy M Walker, James A Watson, David A J Moore, Mike Frick, Euzebiusz Jamrozik
Preventive therapy remains key to the elimination of tuberculosis and is typically offered to people with presumptive Mycobacterium tuberculosis infection to prevent active disease. Although the duration of tuberculosis preventive therapy has been reduced substantially over time,…
Horia Mocanu, Adela-Ioana Mocanu
… provides significant contributions to the understanding of tuberculosis in the field of otorhinolaryngology. It highlights the diagnostic challenges posed by the rare ENT manifestations of tuberculosis, which are often mistaken for more common conditions such as neoplasms or chr…
Sriram Krishnamoorthy, Kalpana Ramachandran
…caused a severe dent in the decades of progress achieved in tuberculosis control and elimination measures, indicating that these measures need to be more structured and resilient. This manuscript focuses on the impact of the COVID-19 pandemic on TB control and also on the measure…
Matthew J Saunders, Delia Boccia, Palwasha Y Khan, Lara Goscé, Antonio Gasparrini, et al.
… is likely to exacerbate a range of determinants that drive tuberculosis, the world's leading cause of death from a single infectious agent. However, tuberculosis is often neglected in wider climate health discussions. Commissioned by WHO, we developed an analytical framework out…
Dan Ye, Ning Gan, Yang Yang, Zhentao Fei, Huarui Liu, et al.
**BACKGROUND:** To examine the clinical features of adrenal tuberculosis to improve clinicians' diagnostic accuracy and treatment strategies. **METHODS:** We report on nine patients diagnosed with adrenal tuberculosis at the Shanghai Public Health Clinical Center between January…
Tyler S Brown, Kristin Nelson, Stephen Kissler, Leo Martinez, C Robert Horsburgh, et al.
Tuberculosis remains a persistent threat to global public health. Ultimately, future progress towards tuberculosis elimination is contingent on our ability to interrupt Mycobacterium tuberculosis transmission between individuals who are infectious and their susceptible contacts. …
Karthikeyan Sundaram, Sathyapriya Subramani, Venkataraman Prabhu
Mycobacterium tuberculosis (MTB) causes Tuberculosis (TB), which is a fatal infectious disease. Timely diagnosis of tuberculosis is crucial, and the conventional culture method is time-consuming and smear microscopic staining is less sensitive. Significantly, rapid molecular diag…
Sandy B. Primrose
The principal diseases caused by mycobacteria are tuberculosis and leprosy. Descriptions of both diseases can be found in pre-Christian Greek literature and DNA from both has been recovered from ancient skeletons. Leprosy is caused by <italic>Mycobacterium leprae</italic> and <it…
Yinfeng Su, Xingxing Kong, Zhanpeng Chen, Xiaomin Wang, Shuihua Lu
Tuberculosis in pregnancy is a series of diseases caused by(). Exact global incidence rates are difficult to obtain and are expected to be similar to those in the general population, with potentially higher rates in developing countries. Tuberculosis in pregnancy is associated wi…
Jalaledin Ghanavi, Poopak Farnia
Tuberculosis and its pathogen, Mycobacterium tuberculosis complex, are a major health challenge. The causative agent of tuberculosis is M. tuberculosis complex and is transmitted through airborne droplets. Tumor necrosis factor-alpha (TNF-α) is one of the cytokines that med…
Vikash Gupta, Rajeev Tandon, Vijeta Niranjan, Ankit Kumar
… bacilli (AFB) in sputum samples is essential for pulmonary tuberculosis diagnosis. Sputum production may be absent in 40-60% of patients with probable pulmonary tuberculosis. Identification of active pulmonary tuberculosis disease patients is an important component of TB control…
M. Rajeswari, Riley Malar, Raheem Unissa, Pechetti Sujjani
Mycobacterium tuberculosis is the bacteria that causes tuberculosis (TB), a communicable disease that mostly affects the lungs but can also affect other regions of body. The World Health Organization (WHO) forecasts that approximately 10 million individuals worldwide contracted t…
Emmanuel M Sindato
Tuberculosis and diabetes are major global health concerns, with their prevalences projected to increase disproportionately in the low- and middle-income countries (LMICs). The convergence of tuberculosis and diabetes impact is also expected to rise, posing a negative synergism t…
Chetan Seshadri, JoAnne L Flynn, Pauline Maiello, Dirk Schnappinger, Robert J Wilkinson, et al.
… vaccine development for infectious diseases. Mycobacterium tuberculosis is a human-adapted pathogen that is the leading infectious cause of death worldwide. M tuberculosis infection results in a spectrum of clinical outcomes that are incompletely modelled in animals. To date, th…
Balasundaram Revathi Mani, Usharani Brammacharry, Venkateswari Ramachandra, Muthuraj Muthaiah
Background: Tuberculosis (TB) is a chronic infectious disease caused by Mycobacterium tuberculosis (MTB), primarily transmitted via airborne particles. The currently recommended methods for diagnosing tuberculosis (TB) include molecular-based tests that can detect both TB and dru…
Prakruthi Shivakumar, Kavitha Sunil Shettigar
Tuberculosis (TB) is caused by a single infectious agent, Mycobacterium tuberculosis, and a public health concern due to increased cases of drug-resistance and high mortality rates. Rapid identification of tuberculosis is necessary for its early treatment and to prevent the emerg…
Rajat Kumar, Khushbu Kumari, K. D. Kulkarni, Swapnil Hiremath, Meghana Prabhu
…in, Auramine-O and ZN stain in rapid diagnosis of pulmonary tuberculosis in sputum cytology. Mycobacterium Tuberculosis (MTB) is most common communicable disease in low socioeconomic population. It is most common in developing countries like India. Study was done on Sputum of cli…
Spasoje Popevic, Nikola Maric, Slobodan Belic, Marija Karapandzic, Sanja Dimic Janjic, et al.
Endobronchial tuberculosis is a rare form of tuberculosis that is characterized by the presence of tuberculous granuloma within the respiratory tract, usually in the trachea or main bronchi. Multiple key notes regarding this form make it difficult to detect and treat, which can l…
Siqi Lin, Qianqian Zhang, Juan Liu, Bojie Lin, Daina Zhao, et al.
The emergence of drug-resistant strains of Mycobacterium tuberculosis (Mtb), coupled with lengthy treatment cycles and adverse side effects of traditional therapies, poses a significant global challenge in the form of tuberculosis (TB). Photodynamic therapy (PDT) generates reacti…
Tuberculosis is a most infectious dangerous health problems caused by the Mycobacterium tuberculosis, the species mainly affects the lungs, it can also spreads to various parts of the body like the brain and the spine and second biggest killer in the world. In this chapter, we ha…
C. Igbeneghu, BM Okanlawon, Japhet M. Olisekodiaka
…f PTC are risk factors exhibiting positive interactions for tuberculosis. Methodology: A total of 210 individuals comprising 110 tuberculosis patients (test group) and 100 apparently healthy subjects (control group) participated in this study. Secretors and non-secretors were det…
Charles O. Thoen, David E. Williams
The mammalian tubercle bacilli, Mycobacterium tuberculosis and Mycobacterium bovis, cause disease in a wide variety of mammals. In humans, domestic animals, nonhuman primates, and certain exotic hoofed animals, disease produced by M. bovis or M. tuberculosis cannot be differentia…
Bonsome Bokolo, Ozakieoniso James Kemelayefa, Ray I Ozolua, Fidelis Ching Poh
…ug effects on blood and some biochemical parameters of anti-tuberculosis drugs among patients with primary tuberculosis infection. Study Design: Non-probability (purposive) sampling technique was employed in this study. Place and Duration of Study: This study was carried out at t…