Showing 1–6 of 6 documents
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Amira Mahmood, Mohammad Bilal Ashfaq, Catherine Drain, Eoin Melby, Michael Hunter, et al.
Tuberculosis remains the biggest global killer from infectious causes, with an estimated 1.25 million deaths per year. The quadruple drug regimen of rifampicin, isoniazid, pyrazinamide, and ethambutol has been standard therapy for 40 years, with good outcomes in patients with dru…
Jamal Hassan Mohamoud
Tuberculosis (TB) remains a major public health concern in Somalia, driven by prolonged conflict, population displacement, fragile health systems, and adverse social determinants of health. Although Somalia has made progress in expanding TB services and achieving favourable treat…
Xiaoyun Du, Keqing Shi, Hao Zhang, Yingzhi Chong
Tuberculosis (TB) remains a leading global health threat, with the rise of drug-resistant (DR-TB) strains posing a significant impediment to disease control. An increasingly recognized and complex challenge is heteroresistance, the coexistence of drug-susceptible and drug-resista…
Sarah Schmidiger, Damien Portevin
(), the causative agent of tuberculosis (TB), has plagued humankind for millennia. Claiming 1.25 million lives in 2023, TB remains the worldwide leading cause of death from a single-infectious agent. Improved vaccines, diagnostics and treatment regimens for drug-susceptible and d…
Aisya Rezki Noeriman, Sumarheni Sumarheni, Aliya Nur Hasanah, Lika Apriani, Prayudi Santoso, et al.
…ved outcomes. However, evidence supporting its benefits for tuberculosis (TB) treatment remains limited. This scoping review evaluated clinical studies on TDM and its impact on TB treatment outcomes. **METHODS:** A scoping review was performed using a systematic search in PubMed…
John W Wilson, Zelalem Temesgen, James T Gaensbauer
…been published for both drug-susceptible and drug-resistant tuberculosis (TB), TB in children, and contacts of patients with drug-resistant TB. The operationalization and application of these recommendations, which reflect favorable clinical trial outcomes, may vary significantly…