Showing 1–18 of 18 documents
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Xingyu Lu, Yiyi Hu, Yue Hu, Fei Zhao, Peiyang Fan, et al.
Tuberculosis (TB) is a serious disease that poses a significant threat to the health of children and adolescents, with(PTB) being the most common type. Due to the lack of specificity in clinical manifestations and symptoms, early screening and diagnosis of pediatric pulmonary tub…
Susanna Esposito, Beatrice Rita Campana, Gaia Giorgia Arnesano, Nicola Principi
Tuberculosis (TB) remains a leading cause of morbidity and mortality worldwide, with children representing a particularly vulnerable population in whom diagnosis is often challenging. Pediatric TB is typically paucibacillary and presents with non-specific clinical manifestations,…
Yang Yang, Dan Ye, Zhentao Fei, Ping Liu, Huarui Liu, et al.
**BACKGROUND:** Pediatric tuberculosis (TB) remains a major global health challenge, characterized by age-specific difficulties especially in diagnosis compared to adults. This review summarizes key advances in pediatric TB diagnostics over the past five years. **METHODS:** Lite…
Ben J Marais, H Simon Schaaf
Tuberculosis (TB) is a major cause of disease and death in young children from TB-endemic countries, especially in areas affected by poverty, social disruption, and human immunodeficiency virus (HIV) infection. This article reviews the disease burden and the natural history of di…
Yuqing Chen, Hui Tang, Jieyuan Zheng, Qing Yang, Dongsheng Han
Tuberculosis (TB) remains a leading global infectious killer, yet traditional diagnostic methods are inadequate. Acid-fast staining suffers from low sensitivity, and mycobacterial culture requires prolonged incubation because of the slow growth of. PCR-based molecular assays allo…
Peter J Kitonsa, Devan Jaganath
**INTRODUCTION:** Pediatric tuberculosis (TB), especially among children co-infected with HIV, remains a significant global health challenge. Traditional sputum-based diagnostics are less effective in this population due to difficulties in sample collection and paucibacillary dis…
Daniel Mashiach, Justin Shon, Raquel Mashiach, Gregory Ayzenberg, Osnat Barazani, et al.
Pediatric tuberculosis (TB) remains a critically underrecognized contributor to global childhood morbidity and mortality, with the highest burden concentrated in low-resource settings. Although children comprise a minority of overall TB cases, mortality is disproportionately high…
Silla Varghese Thomas, Priya Rajendran, Sivakumar Shanmugam
This review provides an insight into pediatric tuberculosis (TB) diagnosis in India. Significant challenges still exist in the accurate diagnosis of pediatric TB due to the paucibacillary status of the bacilli and the nonspecific clinical symptoms. Despite advancements in newer d…
Declan Ikechukwu Emegano, Ilker Ozsahin, Emeje Paul Isaac, Dilber Uzun Ozsahin, Oyibo Saidu Silas, et al.
…EW:** The literature review is pertinent because diagnosing pediatric tuberculosis (PdTB) remains quite challenging, especially in areas with limited resources, due to complications caused by variable generalized symptoms, paucibacillary characteristics, vague clinical manifestat…
Pooja Semwal, Manjit Kaur Saini, Moinak Sen Sarma
Antituberculosis drug-induced hepatotoxicity (ATDIH) is a significant concern while managing pediatric tuberculosis. There is limited data on pediatric ATDIH, and much of the management practices are extrapolated from adult experiences. This article provides a comprehensive overv…
Latifah Alfahad, Ayman Khushaim, Waleed Alhabeeb, Abdullah Alzayed, Musab Almushayqih
Tuberculosis (TB) remains a significant public health concern despite preventive measures, such as the use of the Bacille Calmette-Guérin (BCG) vaccine, which reduces the risk and severity of early-life TB infection. The adverse effects of the BCG vaccine include infection b…
Alessandra Li Pomi, Antonella Gambadauro, Francesca Galletta, Giuseppe Fabio Parisi, Salvatore Leonardi, et al.
…ell as clinically distinct from both thecomplex and. In the pediatric age group, NTM disease manifests with a diverse range of clinical phenotypes. Cervicofacial lymphadenitis stands out as the most common presentation among children who are immunocompetent. Conversely, skin and …
Mina'a Shahid, Kiran Hilal, Memoona Khan, Zainab Haider Ejaz, Sadaf Altaf, et al.
Pediatric liver masses encompass a diverse spectrum of benign and malignant lesions, with distinct patterns based on patient age. Optimal imaging is critical for timely diagnosis, management, and prognosis. This pictorial minireview categorizes pediatric liver masses by age group…
Aanchal Datta, M Vishnu Vardhan, Chhitij Srivastava
… management. Despite using the diagnostic tool, PSH forms a diagnosis of exclusion. Management involves supportive care, pharmacological therapy and, surgical intervention for raised ICP. Detailed analysis of the handful of known cases showcases the grave morbidity this condition…
Mohammed Amin, Khaled Sidani, Mohamad Housheimy, Sarah Kawtharani, Joelle Hassanieh, et al.
**BACKGROUND:** Pediatric spinal epidural abscess is considered to be a rare illness. Despite all the recent improvements in the diagnosis and the treatment of this rare condition, the morbidity and mortality rate is still high especially if the diagnosis was not achieved early o…
Saurav Jyoti Patgiri, Anukalpa Saikia, Sushmita Yadav, Md Atique Ahmed, Luna Adhikari, et al.
…y the extracted cases, and common patterns in presentation, diagnosis, and outcome were examined. **RESULTS:** One hundred and sixty published articles were included after a full text review. The most frequent atypical presentations included neurological involvement (e.g., brain…
Lotte W Nijman, Simona M Cristescu, Robert S Jansen
…ow sensitivity. Especially in the case of HIV co-infection, pediatric patients, EPTB and drug-resistant TB, obtaining adequate samples and detecting and treating TB is challenging. Breath analysis is an alternative tool for TB diagnosis that can potentially overcome the limitatio…
Jayendra Seetharaman
…er disease, cholelithiasis, chronic pancreatitis, abdominal tuberculosis, inflammatory bowel diseases (IBD), parasitic infection, and urinary tract infection (UTI) are prominent organic causes of RAP. The published data from developed countries reported pooled prevalence of FAPD …