Showing 1–25 of 200 documents
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Pankaj Gupta, Lalit Nainiwal
Background: Tuberculosis is deadliest disease killing nearly 2 million people every year. Before the etiologic cause of TB was determined by Koch, cod liver oil and sunlight, both sources of vitamin D, were used in treatment of tuberculosis. After discovery of antibiotics, anti-i…
Anita Nur Charisma, Winariani Koesoemoprodjo
Background: Tuberculosis (TB) in extra-pulmonary organs, such as bone and joint TB, has an incidence rate of 19% of the cases and represents 11-15% of all extra-pulmonary TB. The predilection of bones and joints is the most common predilection with more than 10% of the cases. Gon…
Thobani Ntshiqa, Jeniffer Nagudi, Yohhei Hamada, Andrew Copas, Stacie Stender, et al.
**BACKGROUND:** Although tuberculosis preventive therapy guidelines support testing for tuberculosis infection in household contacts (HHCs), this adds operational complexity and cost and has often been abandoned. To understand utility of testing, we determined prevalence and risk…
T. Nanthini, Karaline Karunagari
Tuberculosis is an infectious disease which spreads from one person to another which has a devastating impact on the economic well-being of the individual, their families, and the entire community. The effective engagement of all health care providers especially nursing personnel…
Khan PY, Paracha MS, Grundy C, Madhani F, Saeed S, et al.
Pakistan is one of the five highest tuberculosis burden countries globally. We estimated prevalence of adult bacteriologically confirmed pulmonary tuberculosis and annual risk of Mycobacterium tuberculosis (M. tuberculosis) infection in children aged 2-4 years in Karachi, Pakista…
Nsubuga G, Kennedy S, Rani Y, Hafiz Z, Kim S, et al.
Background The NOVA Tuberculosis Total Antibody Rapid Test is a commercially available lateral flow serological assay that is intended to be used as an aid in the diagnosis of tuberculosis. We conducted a study to estimate diagnostic accuracy of this assay for diagnosis of active…
Jeong D, Kang HY, Kim J, Lee H, Yoo BN, et al.
… aimed to review the current data composition of the Korean Tuberculosis and Post-Tuberculosis Cohort, which was constructed by linking the Korean Tuberculosis Surveillance System (KNTSS; established and operated by the Korean Disease Control and Prevention Agency since 2000) and…
Bitew A, Bati S
…infection is increasing and often misdiagnosed as pulmonary tuberculosis in developing countries where the prevalence of pulmonary tuberculosis is high. |Therefore, the purpose of this study is to determine the spectrum of potential pulmonary fungal pathogens and the prevalence o…
Berlian Beatrix Rarome, Nurul Aisah, Retno Asih Setyoningrum, Ni Made Mertaniasih
The diagnosis of childhood tuberculosis remains a challenge worldwide. The GeneXpert MTB/RIF test, a rapid Mycobacteria tuberculosis diagnostic tool, was recommended for use in children. No pediatric studies of GeneXpert MTB/RIF assessing pulmonary tuberculosis within a hospital …
Musisi E, Sessolo A, Kaswabuli S, Zawedde J, Byanyima P, et al.
…ted the utility of a novel RNA-based quantitative test, the tuberculosis molecular bacterial load assay (TB-MBLA), for the detection and quantification of Mycobacterium tuberculosis in stool. Stools from 100 adult individuals were treated with OMNIgene-sputum reagent and tested u…
Divya Dayal
Background of the Study: Tuberculosis is a global public health issue despite the discovery of the causal bacterium over 100 years ago and availability of effective medications and vaccines for prevention and cure. Tuberculosis has a global incidence rate of 119 per lakh, with lo…
Joshua Rosenheim, Markos Abebe, Mulugeta Belay, Begna Tulu, Dawit Tayachew, et al.
Human exposure to Mycobacterium tuberculosis (Mtb) is thought to result in a spectrum of outcomes including bacillary clearance, quiescent Mtb infection, incipient tuberculosis, subclinical tuberculosis and active tuberculosis [1]. Incipient tuberculosis - defined as a prolonged …
Adane Bitew, Solomon Bati
…y mycosis is increasing and often misdiagnosed as pulmonary tuberculosis in developing countries where the prevalence of pulmonary tuberculosis is high. Objective: To determine the prevalence of pulmonary mycosis and pulmonary tuberculosis fungal co-infections. Methods: A hospita…
Umar F, Hatta M, Husain DR, Natzir R, Dwiyanti R, et al.
…ssion level of the Rv1250 efflux pump gene in Mycobacterium tuberculosis isolated from individuals with tuberculosis who received drug therapy, at the 1st, 3rd and 5th months, and newly diagnosed patients with tuberculosis who will receive drug therapy (0 month). The study was a …
Agus Khoirul Anam
Abstract: Tuberculosis is an infectious disease caused by germs of a group of mycobacterium namely mycobacterium tuberculosis. The objective of the research is to identify Tuberculosis patients complaints in side effects of drug treatment anti-tuberculosis and factors that influe…
Avula A, Ngu S, Mansour W, Gurala D, Maroun R
…ted with poor prognosis seen in advanced disease, laryngeal tuberculosis (LTB) now represents only 1% of all cases of tuberculosis (TB). The incidence of LTB has decreased drastically with the introduction of anti-tubercular drugs. LTB can be primary or secondary to pulmonary tub…
Berhan A, Almaw A, Solomon Y, Legese B, Damtie S, et al.
Background Tuberculosis is a communicable disease, mainly caused by the bacillus Mycobacterium tuberculosis. Globally, TB is the ninth leading cause of death, with developing countries bearing most of the burden. The discovery of chemotherapy lead to significant improvements in p…
Berhan A, Almaw A, Solomon Y, Legese B, Damtie S, et al.
Background Tuberculosis is a communicable disease, mainly caused by the bacillus Mycobacterium tuberculosis. Globally, TB is the ninth leading cause of death, with developing countries bearing most of the burden. The discovery of chemotherapy lead to significant improvements in p…
Nkechi Eucharia Egbe, Azizat Olatunji, Peter A. Vantsawa
The accurate diagnosis of tuberculosis (TB), detection of drug‐resistant TB and knowledge of the associated risk factors can reduce transmission of TB in the community. Therefore this study was carried out to determine the prevalence of Mycobaterium tuberculosis ( MTB ) and its r…
M. S. Ramya, Jyothi Jadhav, T S Ranganath
Background: Tuberculosis (TB) is a top infectious disease killer worldwide. In India although Revised National Tuberculosis Control Programme (RNTCP) has seen significant success in TB treatment, patient non-adherence or lost to follow up continue to persist and are influenced by…
D. S. Esmedlyaevа, Н. П. Алексеева, Marina Dyakova
…of adverse treatment outcomes in individuals with pulmonary tuberculosis (PT) is relevant due to the worldwide increase in drug resistance of Mycobacterium tuberculosis (MBT) strains to anti-tuberculosis drugs (PTP). Matrix metalloproteinases (MMPs) and their tissue inhibitors (T…
Abebe F, Belay M, Legesse M, K L M C F, Ottenhoff THM
…nvestigate protective and diagnostic immune markers against tuberculosis (TB), we measured antibody isotype responses to Mycobacterium tuberculosis (Mtb) antigens (LAM, Rv2031, and HBHA) in cohorts of 149 pulmonary tuberculosis patients (PTBP), 148 household contacts (HHCs), and …
S. Saxena, Palak Bhikharbhai Patel, Drushi Patel, Ankur Shah
Patellar tuberculosis (TB) is an uncommon occurrence and has been sparsely reported in the literature. Imaging plays a key role in its diagnosis, as clinical symptoms vary and are often unspecific. We present two cases of isolated patellar tuberculosis, its classical imaging feat…
O. A. Zhurilo, A. I. Barbova, P.S. Trophimova, S.V. Mironchenko
…ng the Xpert MTB/XDR method in the algorithm for diagnosing tuberculosis (TB) in Ukraine. Materials and methods. 51 strains of M. tuberculosis (MBT) were studied using Xpert MTB/XDR cartridges, the LPA method and the BASTEC system: 16 MTB strains of the control panel with known r…
Velayutham B, Chadha VK, Singla N, Narang P, Gangadhar Rao V, et al.
…formation on the proportion of new smear-positive pulmonary tuberculosis (PTB) patients treated with a 6-month thrice-weekly regimen under Revised National Tuberculosis Control Programme (RNTCP) who develop recurrent TB after successful treatment outcome. Objective To estimate TB…