Showing 1–25 of 200 documents
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Venkateswari Ramachandra, Usharani Brammacharry, Aaina Muralidhar, Anbazhagi Muthukumar, Revathi Mani, et al.
…stic tool capable of simultaneously detecting Mycobacterium tuberculosis and rifampicin resistance. This study aimed to assess the diagnostic precision of GeneXpert MTB/RIF assay to detect pulmonary and extrapulmonary tuberculosis and evaluate the performance for detecting of rif…
Venkateswari Ramachandra, Usharani Brammacharry, Aaina Muralidhar, Anbazhagi Muthukumar, Revathi Mani, et al.
…stic tool capable of simultaneously detecting Mycobacterium tuberculosis and rifampicin resistance. This study aimed to access the diagnostic precision of Xpert MTB/RIF assay to detect pulmonary and extra-pulmonary tuberculosis and to evaluate the performance for the detection of…
Pham Dinh Dong, Nguyễn Kim Cương, Nguyen Thi Phuong, Nguyễn Ngọc Hồng, Nguyễn Văn Hùng, et al.
…ional TB Program has made great efforts to detect and treat tuberculosis. Objectives: Assessment of Mycobacterial level in sputum before treatment, and susceptibility to the first line anti-TB drugs of M. tuberculosis strains isolated from TB patients with AFB (+) and non-multidr…
Cox H, Salaam-Dreyer Z, Goig GA, Nicol MP, Menardo F, et al.
…ound South Africa has a high burden of rifampicin-resistant tuberculosis (including multidrug-resistant [MDR] tuberculosis), with increasing rifampicin-monoresistant (RMR) tuberculosis over time. Resistance acquisition during first-line tuberculosis treatment could be a key contr…
Dorota Sokół, Arkadiusz Standyło, Jakub Czarnota, Tomasz Skubel, Michał Dobrzyński, et al.
…z-Szczęsna Halina. </strong><strong>The correlation between tuberculosis and diabetes incidence and the impact of mass migration on the development of tuberculosis and drug-resistant tuberculosis on the example of India and England</strong><strong>. </strong><strong>Journal of Ed…
Andarge DB, Anticho TL, Jara GM, Ali MM
Objective Multidrug-resistant Mycobacterium tuberculosis is a public health threat in resource-limited countries where it is easily disseminated and difficult to control. The aim of this study was to determine the prevalence of tuberculosis, rifampicin-resistant/multidrug-resista…
B. Abdullahi, M.A. Shaibu, A.U. Jibrin
Mycobacterium tuberculosis, the causative agent of tuberculosis, is one of the most ancient chronic infectious illnesses and the second greatest cause of infectious death worldwide, behind COVID-19. This study was conducted at the National Tuberculosis and Leprosy Training Center…
Anand Kumar, Aparjot Singh, Sudhir Chaudhri, Sanjay Kumar Verma, Kiran Pandey, et al.
Background: Mycobacterium tuberculosis, most commonly, infects the lungs (pulmonary TB). Most cases of female genital TB (FGTB) are found in premenopausal women, theoretically because an atrophic endometrium provides a poor milieu for mycobacterial growth. Female genital TB gener…
Wubu B, Jemal M, Million Y, Gizachew M
…r areas are important sites for disseminating Mycobacterium tuberculosis among individuals living in such areas. This study examined patients with suspected pulmonary tuberculosis (PTB) visiting the Abrihajira and Metema hospitals in northwest Ethiopia to investigate the prevalen…
Anagoni Srikar, B. V. Ramana, Parnakshi Sarma, Alladi Mohan, Abhijit Chaudhury
Abstract Background: Multidrug-resistant tuberculosis (MDR-TB) is a global public health problem. Methods: We tested 104 strains each of Mycobacterium tuberculosis complex ( Mtb ) isolated from new cases and previously treated cases against four first line anti-tuberculosis agent…
Shaohua Yao, Yan Jy, Li L, Daqing Ma, Jun Liu, et al.
…Wang,1 Aimin Wang,1 Fangjin Bao,1 Zekun Zhang,1 Xundi Bao1 1Tuberculosis Prevention and Treatment Institute of Anhui Province (Anhui Chest Hospital), Hefei 230022, Anhui, People’s Republic of China; 2Affiliated Psychological Hospital of Anhui Medical University, Hefei Fourt…
Dejene TA, Hailu GG, Kahsay AG, Wasihun AG
Introduction Tuberculosis (TB) is the second leading cause of mortality from an infectious disease worldwide. Multidrug-resistant tuberculosis (MDR-TB), where rifampicin-resistant TB is the biggest contributor, remains a global health threat. There is scant data on MTB and rifamp…
Jorwal P, Singh BK, Anand A, Khan F, Khandelwal K, et al.
Background Tuberculosis (TB) is still the second causative agent of death worldwide after COVID-19. It is caused by Mycobacterium tuberculosis (MTB) infection. Objective The aim of the current study was to compare the performance of GeneNAT real-time polymerase chain reaction ana…
Téllez-Navarrete NA, Ramon-Luing LA, Muñoz-Torrico M, Preciado-García M, Medina-Quero K, et al.
Background Tuberculosis (TB) is an infectious disease. During TB, regulatory T cells (Treg) are related to poor prognosis. However, information about conventional and unconventional Treg (cTreg and uTreg, respectively) is limited. The tumour necrosis factor (TNF) and its receptor…
Peter M. Mbelele, Emmanuel Mpolya, Elingarami Sauli, Bariki Mtafya, Nyanda Elias Ntinginya, et al.
Abstract Background Rifampin or multidrug-resistant-tuberculosis (RR/MDR-TB) treatment has transitioned to injectable-free regimens. We tested whether M. tuberculosis ( Mtb ) elimination rates measured by molecular bacterial load assay (TB-MBLA) in sputa correlate with compositio…
Sulistijawati RS, Icksan AG, Lolong DB, Nurwidya F
Background Tuberculosis (TB) remains a burden globally, including Indonesia. The primary objective of this study is to reveal the chest radiography characteristic of drug-sensitive TB (DS-TB) and multi-drug resistant TB (MDR-TB) in the Indonesian national tuberculosis prevalence …
Erkihun M, Kiros T, Berhan A, Ayele B
Introduction. Multi-drug-resistant tuberculosis (MDR-TB) is an emerging global challenge. Ethiopia is one of the 20 top countries with the highest estimated numbers of incidents of MDR-TB. Recently, the World Health Organization warned that drug-resistant TB is escalating and cal…
Sinshaw W, Kebede A, Bitew A, Tesfaye E, Tadesse M, et al.
…ted risk factors among presumptive smear negative pulmonary tuberculosis patients in Addis Ababa, Ethiopia. Methods Analytic cross sectional study design was used. A total of 418 smear negative presumptive pulmonary TB patients were enrolled from selected health facilities since …
Nalunjogi J, Mucching-Toscano S, Sibomana JP, Centis R, D'Ambrosio L, et al.
…s growing on the overall impact of the COVID-19 pandemic on tuberculosis (TB) services, global studies based on national data are needed to better quantify the extent of the impact and the countries' preparedness to tackle the two diseases. The aim of this study was to compare th…
Yao S, Yan J, Li L, Ma D, Liu J, et al.
Background Multidrug-resistant tuberculosis (MDR-TB) is currently a major problem in China. The prevention and treatment work for MDR-TB patients started late in Anhui province. To determine the prevalence of MDR-TB in sputum smear-positive TB patients (SSPTBPs) and analyze the r…
O.I. Sakhelashvili–Bil
Objective — to study the features of multidrug-resistant tuberculosis of the lungs of respiratory organs in children and adolescents from focuses of chemoresistant tuberculosis infection. 
 Materials and methods. To study the features of the course of multidrug-resistant pul…
Ogwang MO, Imbuga M, Ngugi C, Mutharia L, Magoma G, et al.
Introduction Globally anti-tuberculosis drug resistance is one of the major challenges affecting control and prevention of tuberculosis. Kenya is ranked among 30 high burden TB countries globally. However, there is scanty information on second line antituberculosis drug resistanc…
Leonardo Martínez, Neus Altet, F Boulahbal, Joan A. Caylà, Tsira Chakhaia, et al.
…t Objective To evaluate the impact of isoniazid on incident tuberculosis in household contacts of MDR tuberculosis cases. Design Systematic review and individual-participant meta-analysis. Data sources MEDLINE, Web of Science, BIOSIS, and Embase without language restrictions for …
Engel N, Ochodo EA, Karanja PW, Schmidt BM, Janssen R, et al.
…kground Programmes that introduce rapid molecular tests for tuberculosis and tuberculosis drug resistance aim to bring tests closer to the community, and thereby cut delay in diagnosis, ensure early treatment, and improve health outcomes, as well as overcome problems with poor la…
Gebremariam G, Kiros M, Hagos S, Hadush H, Gebremichael A, et al.
Background Tuberculosis (TB) is a major public health concern in the developing countries. Moreover, the emergence of multidrug-resistant tuberculosis is challenging. However, there are no organized data on the trends of pulmonary tuberculosis and rifampicin-resistant Mycobacteri…