Showing 1–7 of 7 documents
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Qi Nie, Yuan Liu, Fan Xiao, Yong Zhou, Tingting Fu, et al.
…extensively drug-resistant tuberculosis (pre-XDR-TB) during pregnancy poses a formidable clinical challenge, particularly when complicated by tuberculous meningoencephalomyelitis (TBMEM), While the WHO operational handbook provides a general framework for drug-resistant TB, robus…
Joelma Patrícia Gonçalves Mateia Pio, Marcelo Nóbrega Litvoc, Hermes Ryoiti Higashino, Vivalda Ndahafa Hinamito, Igor C. Borges
… antimicrobial selection due to its resistance profile, and pregnancy makes this situation even more challenging due to additional restrictions related to the risk of fetal toxicity. Female patient, 31 years old, with a past history of pleural TB in 2018, diagnosed with pulmonary…
Ameya D. Bendre, Pooja Singh, Swati Jaiswal
…s review highlights immune-neuroendocrine reactivity during pregnancy, a state that alters maternal immunity and increases vulnerability to TB (https://doi.org/10.3389/fmed.2025.1503402). Pregnancy introduces unique immunological challenges for TB management. Hormonal changes dur…
Wang L, Zhang X, Wang W, Huang F
We reported a late-pregnancy woman with pre-XDR PTB who had not received regular anti-tuberculosis treatment prior to delivery. Despite this, she successfully delivered a premature baby who exhibited normal growth and development, and subsequently completed her anti-tuberculosis …
David S.C. Hui, Chi Chiu Leung
… in the ongoing TB epidemic.50 The safety of rifapentine in pregnancy remains to be established even though no excess risks of foetal loss or congenital anomalies were observed among pregnant women inadvertently exposed to either isoniazid or isoniazid plus rifapentine in two cli…
Deshpande D, Srivastava S, Bendet P, Martin KR, Cirrincione KN, et al.
The modern chemotherapy era started with Fleming's discovery of benzylpenicillin. He demonstrated that benzylpenicillin did not kill Mycobacterium tuberculosis In this study, we found that >64 mg/liter of static benzylpenicillin concentrations killed 1.16 to 1.43 log 10 CFU/ml be…
Pedersen OS, Holmgaard FB, Mikkelsen MKD, Lange C, Sotgiu G, et al.
Introduction Historically, extensively drug-resistant tuberculosis has been notoriously difficult to treat with devasting outcomes. As we are coming to the end of an era where the 2006 extensively drug-resistant tuberculosis definitions and old treatment regimens are being replac…