Showing 1–25 of 200 documents
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Tanuja Muthyala, Anjali Tempe, Pushpa Mishra, Niharika Dhiman
…is a T helper cell paradigm from T helper1 to T helper 2 in pregnancy and autoimmune diseases may flare or improve in pregnancy depending on the type of autoimmune disease and pre-conception disease activity. There is enough evidence to support that individuals affected with auto…
Li H, Gao M, Dong X, Zhang L, Yuan Y, et al.
…ective This study aimed to investigate the risk factors and pregnancy outcomes associated with recurrent tuberculosis (TB) during pregnancy among patients with a history of TB who underwent in vitro fertilization and embryo transfer (IVF-ET). Methods A retrospective case-control …
Dennis EM, Hao Y, Tamambang M, Roshan TN, Gatlin KJ, et al.
…es. The objective of this study is to explore the risks for pregnancy complications and in-hospital death among mothers diagnosed with TB across racial/ethnic groups in the US. Methods This retrospective cohort study utilized National Inpatient Sample data for all inpatient hospi…
Junita Indarti, Elizabeth Dian Novita, Leonita Triwachyuni Agustina Sutrisna, Rendy Adhitya Pratama
…ived little consideration, especially those affected during pregnancy.Case: A 22-years-old women with two gestations, one parity, one abortion, and one alive child was admitted due to several syncope episodes. It was found that she had cerebral tuberculoma and received appropriat…
Aoi Yamaguchi, Sawa Keymeulen, Zaira N. Chavez Jimenez, Mihiri Karunaratne, Shinya Matsuzaki, et al.
…r respiratory virus transmissions, such as tuberculosis. As pregnancy with tuberculosis is associated with significant maternal morbidity and mortality,3 and given scarcity in data, we examined the possible cause-and-effect of the COVID-19 pandemic and the incidence of pregnancy …
Salazar-Austin N, Cohn S, Lala S, Waja Z, Dooley KE, et al.
Background Both pregnancy and human immunodeficiency virus (HIV) increase the risk of tuberculosis disease, which results in poor maternal, pregnancy, and infant outcomes. Isoniazid preventive therapy (IPT) reduces mortality among individuals living with HIV in high-burden settin…
Walles J, Winqvist N, Hansson SR, Sturegård E, Baqir H, et al.
…ckground Tuberculosis (TB) disease has been associated with pregnancy complications. However, the potential impact of TB infection (TBI) on pregnancy outcome is unknown. To investigate this, we conducted a register-based study in immigrant women screened with QuantiFERON assays f…
Tesfaye F, Sturegård E, Walles J, Bekele B, Bobosha K, et al.
…ntrol of tuberculosis (TB) infection could be influenced by pregnancy. To elucidate this, we longitudinally characterized Mycobacterium tuberculosis (Mtb)-specific and nonspecific immune responses in women during pregnancy and postpartum. HIV-uninfected women without past or curr…
Shakir Atoyebi, Maiara Camotti Montanha, Letisha Najjemba, Catherine Orrell, Lauren Jennings, et al.
… co-infected with HIV and TB, which might be exaggerated in pregnancy. We employed physiologically-based pharmacokinetic (PBPK) modelling to investigate atazanavir pharmacokinetics during coadministration of rifampicin and ATV/r in pregnancy. <h3>Methods</h3> A pregnancy PBPK mod…
LaCourse SM, Wagner AD, Cranmer LM, Copeland A, Maleche-Obimbo E, et al.
…gnant women. Recent trial results suggest increased adverse pregnancy outcomes associated with IPT during pregnancy. Data are limited regarding programmatic IPT use in pregnant PLHIV. Methods We assessed previous programmatic IPT during pregnancy among HIV-infected mothers on enr…
Theron G, Montepiedra G, Aaron L, McCarthy K, Chakhtoura N, et al.
…iving with human immunodeficiency virus (HIV) either during pregnancy or after delivery, showed that IPT during pregnancy increased the risk of composite adverse pregnancy outcomes, but not individual outcomes. Many known factors are associated with adverse pregnancy outcomes: th…
Amaeze OU, Isoherranen N
Pregnancy can increase the risk of latent tuberculosis infection (LTBI) progression to tuberculosis (TB) disease. Isoniazid (INH) is the preferred preventative treatment for LTBI in pregnancy. INH is mainly cleared by N-acetyltransferase 2 (NAT2) but the pharmacokinetics (PK) of …
Nathalie Lachenal, CCH Hewison, Catherine Berry, CD Mitnick, SM Ali Ahmed, et al.
… significant morbidity and mortality risk. Care of DR-TB in pregnancy is even more challenging. A recent meta-analysis examining the impact of DR-TB on pregnancy outcomes found a higher than expected rate of maternal death, pregnancy loss, and a significant prevalence of low-birt…
Kathryn Miele, R. Bryan Rock, Sylvia M. LaCourse, David Ashkin, Lisa Y. Armitige, et al.
…e third of these new cases were reported in women; however, pregnancy status was not included in these data.*CDC recently added pregnancy status to national TB reporting in the United States; however, because the number of U.S. TB cases during pregnancy is presumed to be low, adv…
Mokhele I, Jinga N, Berhanu R, Dlamini T, Long L, et al.
…cribed the safety of second-line anti-TB medications during pregnancy. We aim to describe TB treatment and pregnancy outcomes among pregnant women receiving second-line anti-tuberculosis treatment for MDR/RR-TB in Johannesburg, South Africa. Methods We conducted a retrospective r…
Quincer EM, Gobezayehu AG, Belew ML, Endalamaw LA, Tesfaye YA, et al.
Background Tuberculosis (TB) disease during pregnancy results in adverse maternal and infant outcomes. The development of a TB vaccine with potential for administration during pregnancy or lactation is a priority identified by the World Health Organization. We assessed the accept…
Meehan SA, Hesseling AC, von Delft A, Marx FM, Hughes JA, et al.
…rtality. Pregnant women with TB are at high risk of adverse pregnancy outcomes. This study aimed to determine risk factors for an adverse pregnancy outcome among pregnant women diagnosed with TB. Methods Using TB programmatic data, this retrospective cohort analysis included all …
O'Kelly B, Murtagh R, Lambert JS
…nd the dominant drug class for the management of HIV during pregnancy for the previous decade. As with many drugs used during pregnancy, pharmacokinetic changes decrease exposure to these agents as the pregnancy progresses. This can lead to viral escape at the time of pregnancy a…
Schröder C, Calite E, Böckenhoff P, Büttner T, Stein J, et al.
Aim Less than a dozen cases of psoas abscesses in pregnancy have been described in the literature. We reviewed the literature when treating a patient with a psoas abscess after ipsilateral double J-ureteral stent placement (in the following: "double J-stent") due to infected hydr…
Shafi J, Virk MK, Kalk E, Carlucci JG, Chepkemoi A, et al.
…ter a medication has been licensed, plays a crucial role in pregnancy, as clinical trials often exclude pregnant people. It is important to understand how pregnancy PV projects operate in low- and middle-income countries (LMICs), where there is a disproportionate lack of PV data …
Gupta A, Hughes MD, Cruz JL, Avihingsanon A, Mwelase N, et al.
…ulosis prevention yet data on the safety of first-trimester pregnancy exposure are limited. Methods Planned secondary analysis in a TB prevention trial of adverse pregnancy outcomes among participants assigned to 9-month IPT who became pregnant during (IPT-exposed) or after (unex…
Moro RN, Scott NA, Vernon A, Tepper NK, Goldberg SV, et al.
…ine (P, 900 mg) (3HP) for latent infection treatment during pregnancy. Objectives To assess safety and pregnancy outcomes among pregnant women who were inadvertently exposed to study medications in two latent tuberculosis infection trials (PREVENT TB or iAdhere) evaluating 3HP an…
Jiayu Wen, Jian-Qing He
…acteristics and outcomes of active tuberculosis (TB) during pregnancy after in vitro fertilization-embryo transfer (IVF-ET) with those in natural pregnancies. The aim was to assess the impact of the mode of pregnancy on TB and to gain a deeper understanding of the clinical c…
Ruchi Hooda, Sunita Malik, Deepthi Nair
…ain, pelvic inflammatory infection, infertility and ectopic pregnancy. The average world-wide incidence of female genital tuberculosis in infertile population has been reported as 5-10%, with the range varying between <1% in USA and about 10% in India. Objective: Present study…
Gai X, Chi H, Cao W, Zeng L, Chen L, et al.
Background While miliary tuberculosis (TB) in pregnancy is rare after in vitro fertilization and embryo transfer (IVF-ET), it poses a serious threat to the health of pregnant women and their fetuses. The present study aimed to describe the clinical features of miliary TB and preg…