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Neyro SE, Squassi IR, Medín M, Caratozzolo A, Martínez Burkett A, et al.
Extrapulmonary tuberculosis accounts for 15-20 % of all clinical presentations of tuberculosis. Peripheral tuberculous lymphadenitis is the second most common presentation of extrapulmonary tuberculosis in children, after pleural tuberculosis, in Argentina. We analyzed 92 patient…
Pratik P Padyal, Sandeep M. Bhelkar, Vivekanand B Chachere, Lalitkumar Patle, Teresa Bansod
…ublic health challenge in India, particularly in vulnerable pediatric populations within tribal regions.Despite ongoing efforts under the National Tuberculosis Elimination Programme (NTEP), there is limited data on the epidemiological profile and spatial distribution of pediatric…
Wang DM, Wang C, An Q, Yang Q, Liao Y
…ample, dynamic epidemiology, and characteristic analysis of pediatric tuberculosis (TB) in Southwest China is not clear. Herein, we conducted descriptive dynamic epidemiology, characteristic analysis and geographical distribution study of pediatric TB inpatients in Southwest Chin…
Awang H, Nik Husain NR, Abdullah H
Objectives We sought to determine the total proportion of pediatric tuberculosis cases, characterize tuberculosis by its anatomical location and pretreatment sputum smear status, and to determine the association of the sociodemographic and clinical factors with tuberculosis disea…
Bineeta Kashyap, Neha Gupta, Pooja Dewan, Puneeta Hyanki, NarendraPal Singh
… of disease in TBM. We aimed to assess serum TNF-α level in pediatric patients with TB in association with clinicoradiological and microbiological features, with special reference to TBM. Materials and methods Serum TNF-α level was estimated using enzyme-linked immunosorbent assa…
Enrique G. Villarreal, Ricardo J. Estrada-Mendizábal, Emilia Ramos-Barrera, Pablo D Treviño-Valdez, Oscar Tamez‐Rivera
…cal trends of the different clinical presentations of TB in pediatric population. Methods A retrospective, cross-sectional study, carried out at a pediatric referral hospital in Mexico between 2012-2021. Pediatric patients diagnosed with TB were included. Descriptive statistics w…
…cal trends of the different clinical presentations of TB in pediatric population. Methods A retrospective, cross-sectional study, carried out at a pediatric referral hospital in Mexico between 2012-2021. Pediatric patients diagnosed with TB were included. Descriptive statistics w…
Gupta S, Vats P, Jha A, Singh K, Ghosh S, et al.
…l manifestations of tuberculosis (TB) in the oral cavity in pediatric patients. Study design Four pediatric patients were enrolled in the study. Clinical symptoms, auxiliary examinations, treatments, and outcomes were recorded and analyzed. Four pediatric patients who presented w…
Mohammed Suleiman, Andrés Pérez-López, Ruwa Mohamed, Faheem Mirza, Amina Souli, et al.
…GX-MTB/R) assay, with conventional mycobacterial culture in pediatric non-sputum samples. A total of 417 non-sputum samples from a tertiary pediatric facility underwent simultaneous GX-MTB/R-U and culture testing. Performance was evaluated using conventional culture as a gold sta…
Jyoti Sharma, Sanjeev Chaudhary, Sandesh Guleria, Vipan Garg, Anju Bala
…umptive pulmonary and extrapulmonary tuberculosis (EPTB) in pediatric patients.Materials and methods: It was a descriptive observational study done in pediatric presumptive pulmonary tuberculosis (PTB) and EPTB patients in a tertiary care institute of northern India.Pulmonary as …
Nabaneeta Dash, Maura Manion, Sarah L. Silverberg, Ian Kitai
…FIGURE 1.: An approach to deterioration during treatment of pediatric TB.Lower absolute lymphocyte counts and elevated erythrocyte sedimentation rates have been associated with PRs. Elevated C-reactive protein and D-dimers, together with anemia and low body mass index, are predic…
Ahmad Faried, Satria Prawira Putra, Eka W. Suradji, Trianto, Rafiqa R. Akbar, et al.
…frastructure. A retrospective cohort study was performed on pediatric TBM patients that were admitted to Regional Public Hospital (RSUD) Teluk Bintuni, West Papua, Indonesia (Jan 1st–Dec 31st, 2017). Out of fourty three pediatric tuberculosis patients, there were 7 children with …
Ery Olivianto, Agustin Iskandar, Triyana Dian Dhuha Akmaly, Sarah Zoraya Mirza, Maxie Felix Jahono
…l health challenge, particularly among children. Diagnosing pediatric TB is complicated due to nonspecific symptoms and the difficulty of obtaining sputum samples for microbiological confirmation. Immunological tests, such as the tuberculin skin test (TST) and interferon-gamma re…
Chu P, Chang Y, Zhang X, Han S, Jin Y, et al.
ABSTRACT Pediatric tuberculosis (TB) is a serious infectious disease that affects many children worldwide and is more likely to be extrapulmonary than adult TB. However, the clinical and epidemiological profile, and cost burden of pediatric extrapulmonary TB (EPTB) in China remai…
Gupta N, Kashyap B, Dewan P, Hyanki P, Singh NP
Aim and objectives The paucibacillary nature of pediatric tuberculosis (TB) makes diagnosis difficult. The aim of the study was to correlate the clinical spectrum of pediatric TB with microbiological diagnosis. Materials and methods Specimens from clinically suspected pediatric T…
Pınar Etiz, Ali Tanju Altunsu
…xamine the epidemiologic features and treatment outcomes of pediatric pulmonary tuberculosis cases who were registered to the Adana Tuberculosis Dispensaries. Materials and Methods: Fifty-six pediatric patients aged 0-18 years with the diagnosis of pulmonary tuberculosis were exa…
Dilia Fontalvo-Rivera, Maria Daniels-García, Jesly Doria-Atencia, Karen Tous-Barrios, Liliana Molinares-Núñez, et al.
…y diagnostic methods for EPTB at the point of care (POC) in pediatric patients at a referral hospital. **PATIENTS AND METHOD:** Retrospective study in both male and female patients aged 0-17 years hospitalized from January 2012 to January 2022 in a pediatric referral hospital in…
Drobish I, Ramchandar N, Raabe V, Pong A, Bradley J, et al.
…losis (MTB) complex infections in children and 1%-2% of all pediatric tuberculosis infections. Treatment regimens and durations typically mirror recommendations for other types of extrapulmonary MTB, but there are significant variations in practice, with some experts suggesting a…
Pace D, Pellegrino R, Dalpiaz I, Renni M, Galli L, et al.
Introduction The diagnosis of pediatric tuberculosis (TB) is challenging, due to the lower sensitivity of microbiological tests, such as culture and microscopy, compared to their performance in adult cases. Guidelines have introduced molecular tests, including GeneXpert MTB/ RIF …
Arvind Sharma, Sunita Patel, Prince Kumar Lodhi, Aprajita
…B) is a major global public health threat and its impact on pediatric population is particularly concerning. India has the highest fraction of the world’s TB burden. TB is a disease with high morbidity and mortality. Aiming for eradication in 2025 announced by the honorable Prime…
Vijay Kumar Yadawa, KumariSushma Saroj, Ravindra Prasad
… meningitisin children aged 0–14 years at R.T.H.C Kanti and Pediatrics Department of S.K.M.C.H, Muzaffarpur, Bihar.Methodology: This was a case control study in the Pediatric patients with Meningitis and diagnosed as theTB meningitis by CSF examination at R.T.H.C Kanti and Pediat…
Ian Drobish, Nanda Ramchandar, Vanessa Raabe, Alice Pong, John S. Bradley, et al.
…ted for MTB complex OAI over a 26-year period at a tertiary pediatric center in southern California. Methods We conducted a retrospective review of children diagnosed with MTB complex OAI and cared for between 31 Dec 1992 to 31 Dec 2018 at a single tertiary care pediatric hospita…
Babak Pourakbari, Hani Rostami Rad, Maryam Sotoudeh, Reihaneh Hosseinpour Sadeghi, Shima Mahmoudi, et al.
**BACKGROUND:** Pediatric tuberculosis (TB) remains a significant global health issue due to its diagnostic complexity and paucibacillary nature. This study aimed to evaluate the clinical, diagnostic, and immunological characteristics of pulmonary TB (PTB) and extrapulmonary TB (…
Grønningen E, Nanyaro M, Sviland L, Ngadaya E, Muller W, et al.
Pediatric extrapulmonary tuberculosis (EPTB) is a diagnostic challenge. A new immunochemistry based MPT64 antigen detection test has shown improved sensitivity compared to current laboratory tests. The aim of this study was to implement and validate the test performance in a reso…
Paradkar MS, Devaleenal D B, Mvalo T, Arenivas A, Thakur KT, et al.
Background Pediatric tuberculous meningitis (TBM) commonly causes death or disability. In adults, high-dose rifampicin may reduce mortality. The role of fluoroquinolones remains unclear. There have been no antimicrobial treatment trials for pediatric TBM. Methods TBM-KIDS was a p…