Showing 1–25 of 200 documents
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Goscé L, Bitencourt J, Gupta RK, Arruda S, Rodrigues LC, et al.
…e of implementing different preventive strategies alongside treatment of TB disease, including BCG vaccination and treatment of latent tuberculosis infection (LTBI). Large-scale population level LTBI treatment is not currently part of WHO guidelines which recommend LTBI treatment…
Kendra Brett, Camille Dulong, Melissa Severn
… (i.e., coughing). There are two distinct categories of TB, latent TB infection (LTBI) and active TB disease (also known as active TB)., A person with LTBI is not contagious as they cannot spread the bacteria to others and do not possess any visible symptoms. However, persons wit…
Brett K, Dulong C, Severn M
… (i.e., coughing). There are two distinct categories of TB, latent TB infection (LTBI) and active TB disease (also known as active TB)., A person with LTBI is not contagious as they cannot spread the bacteria to others and do not possess any visible symptoms. However, persons wit…
Kendra Brett, Melissa Severn
…ult in active TB disease, producing instead an asymptomatic latent TB infection. People with latent TB cannot spread the disease to others, but they can develop active TB disease. Symptoms of active TB disease include a bad cough, fever, and weight loss.The current treatment for …
Brett K, Severn M
…ult in active TB disease, producing instead an asymptomatic latent TB infection. People with latent TB cannot spread the disease to others, but they can develop active TB disease. Symptoms of active TB disease include a bad cough, fever, and weight loss. The current treatment for…
Soedarsono Soedarsono
…rganization (WHO) guideline recommended a combination of TB treatment consisting of 2 months of intensive phase with isoniazid (H), rifampisin (R), pyrazinamid (Z), and ethambutol (E), followed by 4 months of continuation phase with HR daily. WHO has updated DR-TB treatment guide…
Kerrigan D, Tudor C, Motlhaoleng K, Lebina L, Qomfu C, et al.
…est, Quantiferon-TB Gold In-Tube Test (QGIT), to screen for latent TB compared to the Tuberculin Screening Test (TST) among PLHIV in South Africa. Methods Fifty-six qualitative interviews were conducted with PLHIV and clinical providers participating in the TEKO trial. We explore…
Calvin Young, Melissa Severn
…e 554 per 100,000 population.There are two stages to TB: 1) latent TB infection, and 2) active TB infection. Latent TB typically occurs immediately following exposure to the bacteria. Although an individual who has latent TB infection will not exhibit any symptoms and they are no…
Young C, Severn M
… 554 per 100,000 population. There are two stages to TB: 1) latent TB infection, and 2) active TB infection. Latent TB typically occurs immediately following exposure to the bacteria. Although an individual who has latent TB infection will not exhibit any symptoms and they are no…
Sumaiya Islam, Dona A. Kiriella, Olutobi Oridota, Avika Dixit
…wide. The World Health Organization (WHO) routinely updates guidelines for the treatment to lateen tuberculosis infection (LTBI) in children with the last update provided in 2020. The objective of our study was to assess the impact of these updates on national LTBI guidelines dev…
Torres T, Brembilla NC, Langley RG, Warren RB, Thaçi D, et al.
…unocompetent individuals, the microorganism can remain in a latent, non-contagious form, however, it may become active under conditions of immunosuppression. Tumour necrosis factor (TNF) inhibitors, which are frequently used for the management of immune-mediated disorders like ps…
Lynn Sosa, Gibril J. Njie, Mark N. Lobato, Sapna Bamrah Morris, William G. Buchta, et al.
…oing transmission. May 17, 2019/68(19);439-443 The 2005 CDC guidelines for preventing Mycobacterium tuberculosis transmission in health care settings include recommendations for baseline tuberculosis (TB) screening of all U.S. health care personnel and annual testing for health c…
Puspa Wardhani, Kelana Kusuma Dharma, Susito Susito
…med to determine the effectiveness of family empowerment in latent screening for TB Infection based on WHO guidelines on the level of TB patient obedience and family burden. The research method was a quasi experimental study involving 36 people (family) of TB sufferers with conse…
Amédine Duret, Emma Thorley, Ayolola Eni‐Olotu, Oishi Sikdar, Padmasayee Papineni
…on with HBV or HCV can lead to an increased risk of adverse treatment outcomes, such as drug-induced liver injury (DILI) in patients with active or latent TB. National guidelines recommend routinely screening for HBV/HCV prior to initiating TB treatment. Our objectives were to 1)…
Medrano BA, Lee M, Gemeinhardt G, Rodríguez-Herrera JE, García-Viveros M, et al.
…ght to identify host factors associated with TB and adverse treatment outcomes in older Hispanics by conducting a cross-sectional study of TB surveillance data from Tamaulipas, Mexico (2006-2013; n = 8381). Multivariable logistic regressions were assessed for older adults (OA ≥65…
Duret A, Thorley E, Eni-Olotu A, Sikdar O, Papineni P
…on with HBV or HCV can lead to an increased risk of adverse treatment outcomes, such as drug-induced liver injury (DILI) in patients with active or latent TB. National guidelines recommend routinely screening for HBV/HCV prior to initiating TB treatment. Our objectives were to 1)…
Suman Saurabh, Pankaj Bhardwaj
The WHO consolidated guidelines on tuberculosis: Module 1, covering preventive treatment and an accompanying operational manual have been released in March 2020.[1] The new guidelines integrate the previously separate algorithms for detection of latent TB infection (LTBI) and the…
Kuscu F, Yildirim F, Erturk D, Cabalak M, Komur S, et al.
Background About 10% of individuals with latent tuberculosis infection (LTBI) develop tuberculosis (TB) disease during their lifetime. People living with HIV (PLWH) have a significantly higher risk of developing tuberculosis disease from latent tuberculosis infection (LTBI) compa…
Sana Sharrack, Caroline Zollinger-Read
…ent the case of a 75-year-old male with no risk factors for latent tuberculosis (TB), who was diagnosed with rheumatoid arthritis and appropriately escalated to adalimumab after failing two csDMARDs. His pre-biologic screen revealed a negative IGRA and normal chest X-Ray. He resp…
…on. Currently, there are no comprehensive clinical practice guidelines providing recommendations for the screening, diagnosis, treatment, and prevention of TB in RD patients. To address this issue, the Collaborative Group for TB Prevention and Control in Patients with RD in China…
Delia Goletti, Seif Al-Abri, Giovanni Battista Migliori, Cecilia S. Lindestam Arlehamn, Pranabashis Haldar, et al.
… bacillus, Mycobacterium tuberculosis. Despite effective TB treatment being available for over 65 years, TB today causes 1.3 million deaths yearly, mostly in low- and middle-income countries. Drug-resistant TB is the leading cause of death owing to antimicrobial resistant disease…
Clare Bristow, Uli Schwab
…an Immunodeficiency Virus (HIV) are at an increased risk of latent Tuberculosis (TB) reactivation. HIV TB concurrent infection increases mortality and reduces patient quality of life. Screening for latent TB allows treatment to commence, preventing reactivation. In accordance wit…
Basu S, Sharma N, Mase S, Sachdeva KS
…enge of effective management to minimise the progression of latent TB infection (LTBI) to TB, thereby interrupting the chain of transmission. Approximately 5%-10% LTBI cases eventually develop TB in their lifetime with the risk being higher in children, people living with HIV/AID…
Ren B, Bai X, Zhang H, Sun L, Fang L, et al.
…sis (TB), and about 90% of those infected have asymptomatic latent infections. It has been reported that 85-90% of newly diagnosed active TB cases evolve from patients with latent tuberculosis infection (LTBI). In approximately 5-10% of patients, LTBI progresses to active TB duri…
Bar-Meir M, Pariente G, Romem A, Wiener-Well Y
Objective Official guidelines recommend tuberculosis (TB) screening programmes for all healthcare workers (HCWs), along with offering treatment when latent TB infection (LTBI) is diagnosed. However, adherence to treatment among HCWs is lower compared with non-HCWs. The aim of the…