Showing 1–25 of 200 documents
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V. V. Sinkov, С. Н. Жданова, О. Б. Огарков, Е. Д. Савилов
Introduction. The spread of drug-resistant tuberculosis necessitates the implementation of novel analytical approaches for assessing epidemiological risks using wholegenome sequencing (WGS) data. Objective. To develop an Integrated Epidemiological Risk Index (IERI) that accounts …
Peiyu Xu, Shenni Liang, Andrew Hahn, Vivian Zhao, Wai Tung 'Jack' Lo, et al.
…forming public health strategies. However, existing genomic epidemiology simulators typically assume conditional independence among these processes: generating transmission trees independently of pathogen evolution, and then superimposing neutral mutations onto fixed genealogies …
Zongying Zhan, Tiancheng Xie, Tianshuo Zhao, Xiyu Zhang, Sihui Zhang, et al.
**OBJECTIVE:** To analyse temporal trends of respiratory infectious diseases (RIDs) in Baiyin City from 2014 to 2023, aiming to explore the epidemiological patterns of these diseases (tuberculosis, scarlet fever, pertussis, measles, influenza, mumps, varicella and rubella) and pr…
Cano-Portero R, Amillategui-Dos Santos R, Boix-Martínez R, Larrauri-Cámara A
The epidemiological surveillance data for tuberculosis in Spain in 2015 is analysed in this report. This information was gathered through cases reported to the Red Nacional de Vigilancia Epidemiológica [National Epidemiological Surveillance Network]. In addition, the update of th…
Inna Friesen, Timo Ulrichs, L. A. Hryshchuk, H. S. Saturska
Objective — to compare the epidemiological situation of chemoresistant tuberculosis in Germany and Ukraine, in addition analyzing the nature and features of chemoresistant tuberculosis in 192 patients treated at the Ternopil Regional TB Dispensary Ukraine during 2017—2018.
 …
Carson J, Keeling M, Ribeca P, Didelot X
…nfluenza H7N7 in the Netherlands to reconstruct its spatial epidemiology. In both cases, we show that incorporating epidemiological data into the genomic analysis allows us to investigate the role of epidemiological properties in the spread of infectious diseases.
Jajou R, de Neeling A, van Hunen R, de Vries G, Schimmel H, et al.
Background Patients with Mycobacterium tuberculosis isolates sharing identical DNA fingerprint patterns can be epidemiologically linked. However, municipal health services in the Netherlands are able to confirm an epidemiological link in only around 23% of the patients with isola…
L.D. Todoriko, O.Ya. Pidverbetskyi, О.С. Шевченко, О.V. Pidverbetska
Military conflicts have a negative impact on the epidemiology of various diseases, among which tuberculosis is in the lead. The increased risk of TB morbidity and mortality associated with war has been observed since World Wars I and II, and several civil wars, among others. Sepa…
Goscé L, Tadesse AW, Foster N, van Kalmthout K, Rest JV, et al.
Background Digital adherence technologies (DATs) with associated differentiated care are potential tools to improve tuberculosis (TB) treatment outcomes and reduce associated costs for both patients and healthcare providers. However, the balance between epidemiological and econom…
П. А. Хромова, V. V. Sinkov, Е. Д. Савилов, О. Б. Огарков
Relevance . The article presents an example of using the method of integral assessment of the epidemiological situation of tuberculosis, which is applied to the main statistical criteria as a more accurate approach in assessing the manifestation of the epidemic process and identi…
Fadil Kryeziu, Violeta Kryeziu, Agron Bytyqi, Sejran Abdushi, Adem Bytyqi
…or influence practices in the field of [Public health & Epidemiology]. These implications could encompass Public health sector in Prizren region. Originality/Value: This study contributes to the literature by emphasizing the originality of the research, either through the sci…
Buenestado-Serrano S, Martínez-Lirola M, Dippenaar A, Sanz-Pérez A, Garrido-Cárdenas JA, et al.
The transition from MIRU-VNTR-based epidemiology studies in tuberculosis (TB) to genomic epidemiology has transformed how we track transmission. However, short-read sequencing is poor at analyzing repetitive regions such as the MIRU-VNTR loci. This causes a gap between the new ge…
Jiomekong A, Camara G
Epidemiological surveillance systems enable collection, analysis and dissemination of information on the monitored disease to different stakeholders. It may be done manually or using a software. Given the poor performances of manual systems, the software approach is generally ado…
Xiaoyu Lu, Yuan Jiang, Rui Zhang, Yangyi Zhang, Jing Li, et al.
**BACKGROUND:** Long-term transmission of multidrug-resistant tuberculosis (MDR-TB) challenges TB control by generating new cases and enabling the emergence of extensively resistant strains. We investigated its epidemiologic and bacterial drivers in Shanghai, China. **METHODS:**…
Sadovska D, Ozere I, Pole I, Ķimsis J, Vaivode A, et al.
Background Tuberculosis remains a global health threat, and the World Health Organization reports a limited reduction in disease incidence rates, including both new and relapse cases. Therefore, studies targeting tuberculosis transmission chains and recurrent episodes are crucial…
Asare P, Asante-Poku A, Osei-Wusu S, Otchere ID, Yeboah-Manu D
…, remains a global health problem. West Africa has a unique epidemiology of TB that is characterized by medium- to high-prevalence. Moreover, the geographical restriction of M. africanum to the sub-region makes West Africa have an extra burden to deal with a two-in-one pathogen. …
Guillén-Nepita AL, Vázquez-Marrufo G, Cruz-Hernández A, García-Oliva F, Zepeda-Gurrola RC, et al.
Tuberculosis control in developing regions with apparent low incidence, like the low-income Mexican state of Michoacán, with mean annual incidence rates below 10/100,000 inhabitants, requires knowledge of the actual behavior of the disease. This can be determined using an epidemi…
Jajou R, Kohl TA, Walker T, Norman A, Cirillo DM, et al.
BackgroundWhole genome sequencing (WGS) is a reliable tool for studying tuberculosis (TB) transmission. WGS data are usually processed by custom-built analysis pipelines with little standardisation between them.AimTo compare the impact of variability of several WGS analysis pipel…
Chan, King-pui Florence, 陳璟珮
…e the possible effects of changes in human behaviour on the epidemiology of respiratory diseases and infections in Hong Kong during the COVID-19 pandemic. The first two chapters of the thesis focus on the effect of universal masking and social distancing on hospitalisations due t…
Menean M, Scandale P, Apuzzo A, Barresi C, Checchin L, et al.
…-threatening inflammatory conditions. Understanding uveitis epidemiology, etiology, and clinical findings is fundamental for a prompt diagnosis and optimal patient management. The aim of the study is to report the epidemiology of uveitis in a national referral center in Northern …
Rina de Zwaan, Gerard de Vries, Ella Ubbelohde, Arnout Mulder, Miranda Kamst-van Agterveld, et al.
Whole genome sequencing (WGS) is able to identify epidemiological links between Mycobacterium tuberculosis isolates. Recent clustering can be ruled out using a pre-defined single nucleotide polymorphism (SNP) threshold. If WGS clusters grow significantly over time limited genetic…
Christian Gortázar
Article Figures and data Abstract eLife digest Introduction Results Discussion Materials and methods Appendix 1 Appendix 2 Data availability References Decision letter Author response Article and author information Metrics Abstract Quantifying pathogen transmission in multi-host …
Nicola Harvey, Guy McGrath, James O'Shaughnessy, Jamie A Tratalos, Brian Byrne, et al.
… health, biosecurity and the economy. The complexity of bTB epidemiology, driven by multiple host species, undetected transmission and incomplete diagnostic sensitivity, makes surveillance and control challenging. Pathogen whole-genome sequencing (WGS) can clarify transmission dy…
Zheng MQ, Li XX, Xu R, Liu S, Rui ZY, et al.
… literature study. In this study, publications on molecular epidemiology were analyzed using bibliometric analysis. The statistical analysis of influential publications, journals, countries and authors was first conducted. Methods The Web of Science database was searched for publ…
Azger Dusthackeer, Mahizhaveni Balasubramanian, Sam Ebenezer Rajadas, Christy Rosaline Nirmal, Padmasini Elango, et al.
**INTRODUCTION:** The rise of drug-resistant tuberculosis poses a significant challenge in patient management. Epidemiological cut-off values define drug resistance in. In our previous study, we reported deviations from the WHO-recommended epidemiological cut-off values and ident…