Showing 176–200 of 200 documents
Sorted by hybrid relevance (keyword + semantic via RRF)
Anthony Harries, Kudakwashe C Takarinda
…ress.METHODS: We performed a cluster-randomized, controlled trial in Ca Mau Province, Vietnam, to evaluate the effectiveness of active community-wide screening, as compared with standard passive case detection alone, for reducing the prevalence of tuberculosis. Persons 15 years o…
Zeliang Yang, Zichun Ma, Zubi Liu, Peibo Li, Yuqin Liu, et al.
…ormance of tNGS was robust regardless of specimen types and clinical symptoms. tNGS also showed a detection potential for other coinfecting respiratory pathogens. More than 90% of tNGS-positive individuals gained drug susceptibility results, which were mainly dependent on bacteri…
Franco JV, Bongaerts B, Metzendorf MI, Risso A, Guo Y, et al.
… WHO Global Index Medicus, as well as the WHO International Clinical Trials Registry Platform (ICTRP) on 3 May 2023 (date of last search for all databases). We placed no restrictions on the language of publication. Selection criteria We included retrospective and prospective coho…
Adrienne Katrin M Guiang-Valerio, Ma Theresa M Collante, Christine B Bernal
…re warranted to optimize pediatric treatment strategies. **CLINICAL TRIAL REGISTRY NAME AND REGISTRATION NUMBER:** N/A. **SUPPLEMENTARY INFORMATION:** The online version contains supplementary material available at 10.1186/s41927-026-00630-2.
Franco JV, Bongaerts B, Metzendorf MI, Risso A, Guo Y, et al.
…ed) and WHO Global Index Medicus, and the WHO International Clinical Trials Registry Platform (ICTRP) on 3 May 2023 (date of last search for all databases); we placed no restrictions on the language of publication. Selection criteria We included retrospective and prospective coho…
Schwab TC, Perrig L, Göller PC, Guebely De la Hoz FF, Lahousse AP, et al.
…ence Core Collection, Global Index Medicus, Google Scholar, ClinicalTrials.gov, and the WHO International Clinical Trials Registry Platform for published and unpublished reports on targeted NGS for drug-resistant tuberculosis from Jan 1, 2005, to Oct 14, 2022, with updates to our…
Manon Lounnas, Eden Ngu Masama, Samuel Beneteau, Kunda Kasakwa, Rodney Kaitano, et al.
…d questionnaire at all sites. This study is registered with ClinicalTrials.gov (NCT04203628) and the Pan African Clinical Trial Registry (PACTR202006814433059). **FINDINGS:** Of the 216 children enrolled between Jan 13, 2020, and Dec 31, 2021, 215 were included in the study and …
Camila Massae Sato, Omar Ariel Espinosa, Gutembergue Santos de Sousa, Fabiane Verônica da Silva, Roberta Olmo Pinheiro, et al.
…ntacts of multibacillary leprosy cases. </sec> <sec> <title>CLINICALTRIAL</title> Brazilian Registry of Clinical Trials (ReBEC), RBR-6yg2z9. Retrospectively registered on 3 de Out. de 2019. </sec>
Stefan Fabian Weber, Anne Glaser, Bayodé Roméo Adegbite, Jabar Babatunde Pacome Agbo Achimi Abdul, Guy Arnault Rogue Mfoumbi Ibinda, et al.
…uartile range 28-57). PTB was confirmed in 34 of 103 (33%), clinically diagnosed in 5 of 103 (5%), and not diagnosed in 62 of 103 (62%). In the non-TB group, CXR findings were consistent with bacterial pneumonia (24/62, 39%) or malignancy (12/62, 19%). At follow-up, 81 of 100 (81…
Padmapriyadarsini C, Das M, Burugina Nagaraja S, Rajendran M, Kirubakaran R, et al.
…ods We conducted a literature search for randomized control trials, cohort studies, and case reports of chemoprophylaxis for pediatric contacts of MDR-TB patients in PubMed, EMBASE, Cochrane Databases of Systematic Reviews, metaRegister of Controlled Trials, and other clinical re…
Singh S, Diwakar A, Singh RK
… withdrawal of BCG vaccination mandates from developed industrialized countries while reducing to a single neonatal shot in the rest. Concurrently, a steady increase in early childhood Brain and CNS (BCNS) tumors has occurred. Though immunological causes of pediatric BCNS cancer …
Ndege R, Ngome O, Vanobberghen F, Bani F, Temba Y, et al.
…ts with suspected extrapulmonary tuberculosis. Methods This trial in adults with suspected extrapulmonary tuberculosis was performed in a rural and an urban hospital in Tanzania. Participants were randomized 1:1 to intervention or routine care, stratified by site and HIV status. …
Maraba N, Orrell C, Chetty-Makkan CM, Velen K, Mukora R, et al.
…andard of care clinics will be conducted. Significance This trial will provide evidence for the use of an intervention, including medication monitors and differentiated care package, to improve adherence to TB treatment. Improved adherence should also improve TB treatment complet…
Bogers SJ, Schim van der Loeff MF, Davidovich U, Boyd A, van der Valk M, et al.
…iated with a prevalence of undiagnosed HIV > 0.1%, or whose clinical management would be impeded if an HIV infection were undiagnosed. IC-guided HIV testing is an effective strategy in identifying undiagnosed HIV, but opportunities for earlier HIV diagnosis through IC-guided test…
Story A, Aldridge RW, Smith CM, Garber E, Hall J, et al.
…icentre, analyst-blinded, randomised controlled superiority trial in 22 clinics in England (UK). Eligible participants were patients aged at least 16 years with active pulmonary or non-pulmonary tuberculosis who were eligible for DOT according to local guidance. Exclusion criteri…
Jane E. Gross, Silvia M. Caceres, Katie R. Poch, Nabeeh A. Hasan, Rebecca M. Davidson, et al.
…rol guidelines. This study will systematically characterize clinically-relevant NTM isolates of CF healthcare environmental dust and water biofilms and set the stage to describe the most common environmental sources within the healthcare setting harboring clinically-relevant NTM …
Christina S. Thornton, Nicole Boechler, Vidhi Desai, Ranjani Somayaji, Swathi Purighalla, et al.
…adian Bronchiectasis and Nontuberculous Mycobacterial (NTM) Registry aims to 1) outline the clinical characteristics and natural history of bronchiectasis in Canada, 2) identify risk factors contributing to disease progression within Canadians, 3) integrate comprehensive clinical…
Theodore G. Liou, Frederick R. Adler, Natalia Argel, Fadi Asfour, Perry Brown, et al.
… fibrosis (CF) disease outcomes would increase the power of clinical trials and contribute to better personalization of clinical assessments. A representative patient cohort would improve searching for believable, generalizable, reproducible and accurate biomarkers. METHODS: We r…
Yuli Lily Hsieh
…ologies to enhance the quality of evidence translation from clinical trial findings into real-world healthcare decisions. Decisions on whether to adopt new healthcare technologies often rely on evidence from randomized controlled trials (RCTs). However, trial and target populatio…
Jonas DE, Riley SR, Lee LC, Coffey CP, Wang SH, et al.
…USPSTF). Data sources PubMed/MEDLINE, Cochrane Library, and trial registries through December 3, 2021; references; experts; literature surveillance through January 20, 2023. Study selection English-language studies of LTBI screening, LTBI treatment, or accuracy of the tuberculin …
Erin Boland, Halle R Amick, Leila C. Kahwati, Daniel E Jonas, Cynthia Feltner, et al.
…ing its 1996 recommendation. MEDLINE, Cochrane Library, and trial registries, searched through August 3, 2015; references from pertinent articles; and experts. Literature surveillance was conducted through May 31, 2016. English-language studies of LTBI screening, LTBI treatment w…
Sweeney S, Gomez G, Kitson N, Sinha A, Yatskevich N, et al.
…mic evaluation (PRACTECAL-EE substudy) alongside an ongoing clinical trial (TB-PRACTECAL) aiming to assess the costs to patients and providers of new regimens, as well as their cost-effectiveness and impact on participant poverty levels. This substudy is based on data from the th…
C.A. Celis-Preciado, Simon Leclerc, Martine Duval, Dominic O. Cliché, Pierre Larivée, et al.
…r utility in acute asthma is unclear. We speculate that the clinical and biological response to those treatments varies according to inflammometry and microbiological test results. Methods and analysis An observational longitudinal pilot study with multimodal clinical and transla…
Mukora R, Maraba N, Orrell C, Jennings L, Naidoo P, et al.
…heir treatment journey and help overcome TB-related stigma. Trial registration number Pan African Trial Registry PACTR201902681157721.
Stefano Aliberti, Luigi Ruffo Codecasa, Andrea Gori, Giovanni Sotgiu, Maura Spotti, et al.
…This manuscript describes the protocol of the first Italian registry of adult patients with respiratory infections caused by NTM (IRENE). Methods: IRENE is an observational, multicenter, prospective, cohort study enrolling consecutive adult patients with either a NTM respiratory …