Showing 151–175 of 200 documents
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Noor AM, Ghazali SM, Bakar ZA, Ruzan IN
…ostic tools are critically needed to diagnose Mycobacterium tuberculosis and rifampicin resistance in AFB smear-negative samples. In this study, we evaluated the diagnostic performance of Xpert MTB/RIF Ultra (Ultra) as a rapid test to diagnose tuberculosis in smear-negative cases…
Atherton RR, Cresswell FV, Ellis J, Skipper C, Tadeo KK, et al.
…ion recommended the Xpert ® MTB/RIF Ultra assay (Ultra) for tuberculosis (TB) diagnosis. Ultra offers improved analytical sensitivity when compared with the initial Xpert ® MTB/RIF (Xpert) assay for the detection of Mycobacterium tuberculosis. Ultra is therefore likely to be of p…
Varghese B, Enani M, Alrajhi A, Al Johani S, Albarak A, et al.
…ckground Growing evidences suggested that the Mycobacterium tuberculosis complex (MTBC) lineages can determine the clinical outcome of pulmonary and extra-pulmonary tuberculosis. However, limited data only available revealing such association of bacterial genotypes and clinical p…
Fang Y, Zhou Q, Li L, Zhou Y, Sha W
…udy aimed to investigate the epidemiology of extrapulmonary tuberculosis (EPTB) and analyse the epidemiological characteristics of EPTB patients with or without pulmonary tuberculosis (PTB). EPTB cases admitted in our hospital from January 2015 to December 2020 were included. Uni…
Santhanam Naguthevar, Deepak Kumar, Akshatha Ravindra, Subhashree Samantaray, Sarika Kombade, et al.
Abstract Background Extrapulmonary tuberculosis (EPTB) is quite prevalent in India, ranging from 8.3% and 13.1%. Diagnosis of EPTB is often challenging as it resembles other granulomatous conditions pathologically. TB culture remains the gold standard for definitive diagnosis, bu…
Nikita Birhman, Nikhil Payal, Manisha Khandait, Mohit Bhardwaj
Abstract Background: Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis , primarily affecting the lungs. While pulmonary TB (PTB) is the most prevalent form, comprising the majority of cases, extrapulmonary TB (EPTB) presents unique diagnostic and the…
Anil Kumar Gupta, Amit Singh, Saumya Srivastava, Arti Shrivas, Anvita Gupta Malhotra, et al.
Objectives: Tuberculosis (TB) is curable if diagnosed correctly and promptly. However, the lack of effective and accessible point-of-care tests hindered the systematic screening of TB. The current TB diagnostic methods, including molecular tests, have failed to deliver the capaci…
Shivanand Gundalli, Surekha U Arakeri
A BSTRACT Background: Extrapulmonary tuberculosis (EPTB) was underdiagnosed due to its varying and nonspecific symptoms and limited diagnostic tools. Recent data suggest that there is an increase in the incidence of EPTB due to the availability of the newer diagnostic tools. Obje…
Wenting J, Yuyan M, Qingfeng S, Yao Z, Yumeng Y, et al.
Background and purpose abdominal tuberculosis (TB) is a common form of extrapulmonary TB but it is still a diagnostic dilemma in clinical practice. This study aimed to highlight the clinical features and diagnostic approaches for abdominal TB. Methods seventy cases of diagnosed a…
van Heerden JK, van Zyl A, Schaaf HS, Frigati LJ, Goussard P, et al.
Background Tuberculosis (TB) and childhood cancers have overlapping presentations and malignancies may be misdiagnosed as TB in high TB-burden settings. Methods This retrospective study investigated the diagnosis of TB in children with cancer registered in the Tygerberg Hospital …
Badr Aljarallah
Objective: Intestinal tuberculosis (ITB) is an important form of extrapulmonary TB that often mimics other gastrointestinal diseases, making early diagnosis and management challenging. This study aimed to assess the clinical features, diagnostic approaches and treatment response …
Ule Belotti NC, Madela NK, Tonelli Nardi SM, Mariano DC, de Souza NG, et al.
Background The Xpert Mycobacterium tuberculosis Rifampicin (MTB-RIF) is a technological innovation that presents precision and speed in the diagnosis of tuberculosis (TB). The study aimed to evaluate the performance of Xpert MTB/RIF in the TB diagnosis and compare its results wit…
Niu T, He F, Yang J, Ma C, Xu J, et al.
Background Pulmonary tuberculosis (PTB) complicated with extrapulmonary tuberculosis (EPTB) infection can aggravate the disease, but there have been few reports. Methods Retrospective analysis was used to collect the clinical data of PTB patients with pathogen positive in a teach…
Rashmi M. Karigoudar, Mahesh H. Karigoudar, Sanjay M. Wavare, Lakshmi Kakhandki, Smitha Bagali
Objective: Tuberculosis is an airborne infection caused by Mycobacterium tuberculosis. Timely diagnosis and treatment are important to prevent the spread of infection. Cartridge-based nucleic acid amplification test (CBNAAT) provides a valuable tool in the early detection of TB. …
Rakhee Khanduri, Amita Mason, Varuna Jethani, Ankit Aggarwal, Sushant Khanduri, et al.
Tuberculosis (TB) is a major health concern. It is a contagious disease caused by Mycobacterium tuberculosis. The disease can present in almost all sites-pulmonary and extrapulmonary. We always consider TB in our differentials. The commoner presentations are picked up early and t…
İlkay Bahçeci
Aim: Despite the developments every passing year, tuberculosis is still a major public health problem in Turkey and in the world. Early and correct diagnosis is important for the control of the disease. The aim of this study is to investigate the diagnostic efficiency of the cult…
Hoel IM, Syre H, Skarstein I, Mustafa T
The diagnosis of extrapulmonary tuberculosis (EPTB) is often challenging due to paucibacillary nature of the disease. Xpert MTB/RIF Ultra (Ultra) has been developed to improve detection of Mycobacterium tuberculosis complex (MTC) in paucibacillary specimens. The objective of the …
Jain S, Bajgai P, Kaur S, Dogra M, Sharma A, et al.
… To describe the prevalence and clinical findings of ocular tuberculosis (TB) in Human immunodeficiency virus (HIV) and systemic TB co-infected patients. Methods : In this prospective, observational, non-comparative case series, we included HIV and systemic TB co-infected patient…
Ozbakir H, Guner Ozenen G, Ergun D, Kacar P, Gulderen M, et al.
Background Tuberculosis (TB) infection is transmitted by sharing the same airway with people with active TB. Children are often not considered the source of TB bacilli, and index case investigation is carried out after diagnosis. Here, we describe the impact of the presence of a …
Uddin MKM, Ather MF, Rahman A, Nasrin R, Rahman SMM, et al.
Tuberculosis (TB) remains one of the leading causes of death and Bangladesh ranks 7th among the highest TB burden countries. Though molecular epidemiological data for pulmonary TB (PTB) have previously been described in Bangladesh, data on the molecular characterization and clini…
Weber SF, Saravu K, Heller T, Kadavigere R, Vishwanath S, et al.
Diagnosing extrapulmonary tuberculosis (EPTB) is challenging. Point-of-care ultrasound (POCUS) for human immunodeficiency virus (HIV)-associated EPTB is applied in sub-Saharan Africa. This study aimed at evaluating the applicability of POCUS for diagnosing EPTB in HIV-positive an…
Esra Gürbüz, Saim Türkoğlu, Hakan Çilka, Mehmet Ali Çelik
…odalities of the patients followed up with the diagnosis of tuberculosis (TB). Methods: Patients older than 18 years of age who were followed up for TB in Van Central Tuberculosis Dispensary between January 2018 and December 2021 were included in this study. Demographic character…
Maitre T, Bonnet M, Calmy A, Raberahona M, Rakotoarivelo RA, et al.
…s meningitis (TBM) is the most lethal and disabling form of tuberculosis (TB), particularly in sub-Saharan Africa. Current anti-TB treatment is poorly effective since TBM mortality reaches 40% in HIV-negative patients and up to 70% in HIV-co-infected patients. To reduce TBM-induc…
Qian X, Nguyen DT, Lyu J, Albers AE, Bi X, et al.
…ognized as risk factors for dissemination of extrapulmonary tuberculosis (EPTB). However, there are few population-based studies investigating the association between the primary sites of tuberculosis (TB) infection and mortality during TB treatment. De-identified population-base…
Yuliza Yuliza, Alfian Nur Rosyid, Wiwin Is Effendi, Prastuti Asta Wulaningrum, Herley Windo Setiawan
Introduction: Gastrointestinal tuberculosis (GI TB) is quite rare with 3% incidence of all extrapulmonary involvement. Appendicular TB may occur in 0.1 - 3% of cases. Diagnosis is often difficult because the patient usually complains about chronic abdominal pain and fever. A defi…