Showing 151–175 of 200 documents
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Christie Akwaowo, Idongesit Umoh, Oluseyi Motilewa, Victor Umoh, Eno Usoroh, et al.
…ger multicomponent intervention study, a randomised control trial was conducted with CHWs in 18 primary health care (PHC) clusters in Nigeria. The clusters were allocated to three arms: training and cash incentive (A), training only (B), and control (C) arms. Arms (A) and (B) rec…
Ggita JM, Katahoire A, Meyer AJ, Nansubuga E, Nalugwa T, et al.
…sehold contacts who participated in a randomized controlled trial evaluating home sputum collection and delivery of TB results via SMS (Pan-African Clinical Trials Registry #201509000877140). We asked about feelings, beliefs, decisions, and behaviors in response to the SMS result…
Andrew Arnott, Robert Hart, Scott McQueen, M. Watson, Malcolm Sim
…h secretion loads, although there are no randomised control trials evaluating its use. Novel vibrating mesh nebulisers generate a fine aerosol resulting in deeper lung penetration, potentially offering a more effective means of nebulisation in comparison to jet nebulisers. The pr…
Yuhan Bao, Chunxiang Wang, Haiping Xu, Yongjie Lai, Yupei Yan, et al.
…revention and control for pulmonary TB. </sec> <sec> <title>CLINICALTRIAL</title> Chinese Clinical Trial Registry ChiCTR2200055557; https://tinyurl.com/4ray3xnw </sec>
Lung T, Marks GB, Nhung NV, Anh NT, Hoa NLP, et al.
… are unclear due to the absence of evidence from randomised trials. We assessed the costs and cost-effectiveness of an active case finding strategy in Vietnam, where there is a high prevalence of tuberculosis. Methods We conducted an economic evaluation alongside the Active Case …
Ponlagrit Kumwichar, Tagoon Prappre, Virasakdi Chongsuvivatwong
… conversion rates in a 60-day cluster randomized controlled trial with patients with pulmonary tuberculosis (VOT: n=63 and DOT: n=65) with positive sputum acid-fast bacilli smears and 38 observers equally randomized into the VOT and DOT groups (19 observers per group and n=1-5 pa…
Jyoti S. Mathad, Sylvia M. LaCourse, Amita Gupta
…bservational studies or secondary analyses of TB prevention trials of women who became pregnant on study [12, 14]. The first randomized control trial of IPT in pregnancy (TB-APPRISE), demonstrates the importance of including pregnant and postpartum women in TB trials [8]. Gupta e…
Esmail A, Randall P, Oelofse S, Tomasicchio M, Pooran A, et al.
…is issue, we performed an open-label, randomized controlled trial in periurban informal settlements of Cape Town, South Africa, where we TB symptom screened 5,274 individuals using a community-based scalable mobile clinic. Some 584 individuals with HIV infection or symptoms of TB…
Le Wang, Hongsheng Wang, Liangbin Yan, Meiwen Yu, Jun Yang, et al.
…ing. METHODS: We conducted a cluster-randomized, controlled trial to investigate whether single-dose rifapentine is effective in preventing leprosy in household contacts of patients with leprosy. The clusters (counties or districts in Southwest China) were assigned to one of thre…
Goyal JP, Singh S, Bishnoi R, Bhardwaj P, Kaur RJ, et al.
…osis (TB). However, the evidence from randomized controlled trials (RCTs) is inconsistent. Objectives This systematic review and meta-analysis was performed to synthesize evidence regarding role of vitamin D versus placebo for the management of TB. Materials and methods We search…
Saidi SS, Abdul Manaf R
…s and methods A single-blinded, randomized controlled field trial study design was conducted in Melaka from September 2019 until August 2021, involving newly diagnosed PTB patients. The participants were randomized either into the intervention group (FASTEN intervention) or into …
Wang Q, Pang Y, Jing W, Liu Y, Wang N, et al.
… was the time to sputum culture conversion on solid medium. Clinical outcomes of patients were evaluated at the time of treatment completion. Of the 22 patients in the experimental group, 7 (31.8%) met the treatment criterion of "cure" and 1 (4.5%) "complete treatment," for a tot…
Giller DB, Giller BD, Giller GV, Scherbakova GV, Koroev VV, et al.
…d active TB absence verified with computed tomography (CT). Clinical improvement (sputum negativity, closure of caverna, and lack of reactivation for 3 years) was achieved in 81% of cases. Conclusions Comparing the successful results of this technique in the cohort of multidrug-r…
Jackson-Morris A, Masyuko S, Morrell L, Kataria I, Kocher EL, et al.
…eb of Science, EMBASE, Global Health Database, and selected clinical trials registries. Eligible studies were published between 2010 and December 2022, available in English, and report health service delivery programs or policies for the selected disease dyads in LMICs. We identi…
Fox GJ, Nhung NV, Cam Binh N, Hoa NB, Garden FL, et al.
…esistant tuberculosis is a global health priority. However, trials evaluating the effectiveness of treating Mycobacterium tuberculosis infection among contacts of persons with drug-resistant tuberculosis are lacking. Methods We conducted a double-blind, randomized, controlled tri…
Marks GB, Nguyen NV, Nguyen PTB, Nguyen TA, Nguyen HB, et al.
…ress. Methods We performed a cluster-randomized, controlled trial in Ca Mau Province, Vietnam, to evaluate the effectiveness of active community-wide screening, as compared with standard passive case detection alone, for reducing the prevalence of tuberculosis. Persons 15 years o…
Juan Víctor Ariel Franco, Maria-Intí Metzendorf, Agostina Risso, Melanie Boeckmann, Sabrina Schlesinger, et al.
… WHO Global Index Medicus, as well as the WHO International Clinical Trials Registry Platform (ICTRP) on 3 May 2023 (date of last search for all databases). We placed no restrictions on the language of publication. Selection criteria: We included retrospective and prospective coh…
Singh A, Midha V, Kaur K, Mahajan R, Singh D, et al.
…e for induction of remission at 8 weeks. Trail registration Clinical Trials Registry of India [CTRI/2021/10/037641].
Shangguan Y, Guo W, Feng X, Shi Y, Li X, et al.
… is unclear. Methods We conducted an open-label, randomized trial in China, involving newly diagnosed, drug-susceptible pulmonary TB. The control group was treated with the standard 6-month regimen. The experimental group replaced ethambutol with faropenem for 2 months. The prima…
Inbaraj LR, Shewade HD, Daniel J, Srinivasalu VA, Paul J, et al.
… for the studies to be included were; randomized controlled trials or cohort studies that focused on adults with Isoniazid mono-resistant tuberculosis (HrTB) and treated with a Levofloxacin-containing regimen along with first-line anti-tubercular drugs; they should have had a con…
Fu L, Feng Y, Ren T, Yang M, Yang Q, et al.
…ever studied for LTBI. This proof-of-concept study (Chinese Clinical Trials Registry number: ChiCTR2200058346) was the first to explore a novel, rapid, and simple LTBI detection method via breath test on high-pressure photon ionization time-of-flight mass spectrometry (HPPI-TOFMS…
Menghang Wu, Xiaorong Yin, Maojun Chen, Yan Liu, Xia Zhang, et al.
…long-term prognosis.The study was registered in the Chinese Clinical Trial Registry on May 16, 2015 (ChiCTR-IOR-15006441).
Menghang Wu, Xiaorong Yin, Maojun Chen, Yan Liu, Xia Zhang, et al.
…long-term prognosis.The study was registered in the Chinese Clinical Trial Registry on May 16, 2015 (ChiCTR-IOR-15006441).
Menghang Wu, Xiaorong Yin, Maojun Chen, Yan Liu, Xia Zhang, et al.
…long-term prognosis.The study was registered in the Chinese Clinical Trial Registry on May 16, 2015 (ChiCTR-IOR-15006441).
Marcy O, Wobudeya E, Font H, Vessière A, Chabala C, et al.
…ortality. Methods We did a stepped-wedge cluster-randomised trial in 16 hospitals from six countries (Cambodia, Cameroon, Côte d'Ivoire, Mozambique, Uganda, and Zambia) with high incidence of tuberculosis. Children younger than 5 years with WHO-defined severe pneumonia received e…