Showing 151–175 of 200 documents
Sorted by hybrid relevance (keyword + semantic via RRF)
Odafe S, Onotu D, Fagbamigbe JO, Ene U, Rivadeneira E, et al.
…ed HIV testing among children aged 0-14 years, we evaluated pediatric HIV-positivity rates in points of service in select health facilities in Nigeria. Methods We conducted a retrospective analysis of HIV testing and case identification among children aged 0-14 years at all point…
Ma HW, Lee HS, Ahn JY
…e target for reducing the infection rate. The management of pediatric LTBI is especially crucial because children can serve as a long-term source of infection upon developing active tuberculosis. Therefore, it is important to assess pediatric LTBI using contact investigation and …
Zhao A, Butala N, Luc CM, Feinn R, Murray TS
Pediatric patients with untreated tuberculosis infection (TBI), also called latent TBI, are at risk of progression to active TB disease. The primary aim of this study was to identify factors associated with higher rates of missed appointments and failure to complete therapy for p…
Betül Okuyan, Fatih Tok, Sevgi Karakuş, KAYMAKÇIOĞLU, BEDİA, Mesut Sancar
…soniazid (INH), rifampicin (RIF), and pyrazinamide (PZA) in pediatric tuberculosis patients. The study was carried out in 3 different training-research hospitals in Istanbul, Türkiye between 2011 and 2012. The pediatric patients (aged ≤14 years) who initiated the standard primary…
Jakhar S, Bitzer AA, Stromberg LR, Mukundan H
…l ages. However, the disease presents a larger challenge in pediatric populations, partially owing to the lack of reliable diagnostic standards for the early identification of infection. Currently, there are no biomarkers that have been clinically validated for use in pediatric T…
Nissa Prima Sari Nissa Prima
…s (SES), healthcare support, and medication adherence among pediatric TB patients in Solok, West Sumatera, Indonesia. </p> <p style="font-weight: 400;"><strong>Methods:</strong> A cross-sectional study was conducted involving 57 pediatric TB patients. Data…
Jun Komukai, Kaori Yamamoto, Osamu Tokunaga, Hiharu Inoue, Takayuki Wada
This study examined pediatric tuberculosis (TB) cases in Osaka City from 2008-2023, focusing on diagnostic methods and molecular epidemiology using variable number of tandem repeats (VNTR) analysis and whole-genome sequencing (WGS). Among 29 children aged 0-14 years (notification…
Harichander S, Wiafe E, Mensah KB, Bangalee V, Oosthuizen F
…te the incidence of TB and drug-resistant (DR) TB among the pediatric population. It also reviews the therapeutic options available to treat the condition. Methods A comprehensive search for all relevant evidence was conducted. The following databases were searched: MEDLINE, CINA…
Zhu Y, Gan M, Ge M, Dong X, Yan G, et al.
…sis of infectious diseases in adults, while its efficacy in pediatric infections remains uncertain. We performed a retrospective analysis of 1,493 mNGS samples from pediatric patients with blood, central nervous system, and lower respiratory tract infections. The positive percent…
A J Cabrera Goncalves, B C Adkinson, D Ashkin
Abstract Introduction Interventional bronchoscopy in pediatrics is challenging due to small airway caliber, limited pulmonary reserve, and scarce appropriately sized instrumentation. Expertise is often concentrated in high-volume centers, making complex airway interventions diffi…
Rachmawan Ivan, Munif Badrul, Rois Muhamad, As'ari Hasim, Atik Pramesti,, Wilujeng
…cation framework designed to improve treatment adherence in pediatric TB patients by integrating game elements into the therapy monitoring process. The gamification framework was developed using a user-centered approach by identifying factors influencing adherence through intervi…
Sharma S, Sarin R, Sahu G, Shukla G
Background Pediatric tuberculosis (TB) constitutes 8% of the total caseload of TB. Children are particularly vulnerable to dissemination of disease and mortality. Aim To determine mortality rate, elucidate type of TB, causes and predictors of mortality, if any, in admitted pediat…
Jayagandan S, Singh J, Mudliar SR, Shankar P, Maurya AK, et al.
…ective Microbiological confirmation of tuberculosis (TB) in pediatric cases is challenging due to its paucibacillary nature and difficulty in specimen collection. This study aimed to validate stool as an alternative sample for the diagnosis of pediatric pulmonary TB via Xpert MTB…
Matúš Dohál, Peter Kunč, Jaroslav Fábry, Igor Porvazník, Ivan Solovič, et al.
…ulous mycobacteria (NTM) are rare but emerging pathogens in pediatric populations, particularly in countries where BCG vaccination has been discontinued. Their diagnosis is often delayed due to nonspecific symptoms and limited microbiological sensitivity. **METHODS:** We conduct…
Jamoussi M, Benrhouma H, Miladi Z, Ben Younes T, Klaa H, et al.
…the nervous system. Although it is more frequent in adults, pediatric cases have been reported in endemic countries and it is potentially a deadly affection. Therefore, any unusual neurological manifestation in a formerly healthy child, independently of their vaccination status, …
Gaensbauer J, Broadhurst R
…ests and broader application in non-sputum samples for both pediatric pulmonary and extrapulmonary tuberculosis. Finally, recent studies have provided solid evidence in support of shorter treatment courses for pediatric latent tuberculosis infection, such as 12 weeks of weekly is…
Mejia- Mertel J, Rojas -Hernandez J
…nical manifestations in HTLV-1, still studies are needed in pediatric population to improve diagnosis and treatment of infected patients. Methods Descriptive, retrospective cohort study, conducted in our referral pediatric hospital in Cali, Colombia. Included pediatric patients (…
Kumar NP, Hissar S, Thiruvengadam K, Banurekha VV, Suresh N, et al.
Pediatric TB poses challenge in diagnosis due to the paucibacillary nature of the disease. We conducted a prospective diagnostic study to identify immune biomarkers of pediatric TB and controls (discovery cohort) and obtained a separate "validation" cohort of confirmed cases of p…
Chu P, Chang Y, Zhang X, Han S, Jin Y, et al.
ABSTRACT Pediatric tuberculosis (TB) is a serious infectious disease that affects many children worldwide and is more likely to be extrapulmonary than adult TB. However, the clinical and epidemiological profile, and cost burden of pediatric extrapulmonary TB (EPTB) in China remai…
DesJardin CP, Chirenda J, Ye W, Mujuru HA, Yang Z
Background Historical neglect of pediatric tuberculosis (TB), compounding the absence of a universally effective vaccine, highlights the importance of successful treatment in combating the global epidemic. Furthermore, compliance with international standards of pediatric TB treat…
Neha Gupta, Bineeta Kashyap, Pooja Dewan, Puneeta Hyanki
…s. We aimed to study the serum levels of IL-12 and IFN-γ in pediatric tuberculosis and their correlation with clinical and microbiological features. Material and Methods: A case-control study was conducted on 60 microbiologically confirmed (smear and/or culture and/or cartridge-b…
Gebremichael B, Abebaw TA, Moges T, Abaerei AA, Worede N
…limited. Therefore this study aimed to assess predictors of pediatric Tuberculosis in Public Health Facilities. Methods Unmatched case control study among a total samples of 432 (144 cases and 288 controls) were done from August to December 2016 in Bale zone, South East Ethiopia.…
Eugenia Legan, J.L. Bessich, Alexander M. El‐Ali, Eleanor D. Muise
… the use of bronchial airway stents has been limited within pediatrics. In adults, airway stents serve to maintain airway patency in both intrinsic and extrinsic disease, with most stents placed for malignant disease. In adults with tracheobronchomalacia, a trial of silicone sten…
Christine Anterasian, Kim Dill-McFarland, Josh Ivie, Humphrey Mulenga, Justin Shenje, et al.
…host genetic variation is associated with susceptibility to pediatric tuberculosis disease and blood biomarker expression. Methods We used a case-control study with a 12–36-mo prospective observation period to examine susceptibility to tuberculosis in children aged 2 mo to 5 yr w…
Dong-Hyun Lee, Young‐Jin Choi, Jieun Kim, Eunhee Han, Mi Hyun Bae
…bution of bacterial species in NPS specimens collected from pediatric and adult patients by employing RT-PCR (Allplex respiratory panel 4, RP4, Seegene) to estimate its applicability in a panel-based assay for detecting respiratory viruses. Methods: We used 271 and 173 NPS specim…