Showing 126–150 of 200 documents
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Bo Su, Yong Fang, Na Wang, Liang Tang, Xiaojun Yang, et al.
…onsuming and of low sensitivity for the diagnosis of active tuberculosis (ATB). The purpose of this study is to investigate the accuracy of CD27 - CD38 + IFN-γ + CD4 + /CD4 + for active tuberculosis (ATB) diagnosis. Methods: This prospective diagnostic accuracy study was conducte…
Yong Fang, Na Wang, Liang Tang, Xiaojun Yang, Yuan Tang, et al.
…onsuming and of low sensitivity for the diagnosis of active tuberculosis (ATB). The purpose of this study is to investigate the accuracy of CD27 - CD38 + IFN-γ + CD4 + /CD4 + for active tuberculosis (ATB) diagnosis. Methods: This prospective diagnostic accuracy study was conducte…
I. Mouslim, Chaimae Jioua, Abdelfettah Touibi, S. Ouahid, F. Nejjari, et al.
…apy between 2021 and 2024. Results The prevalence of latent tuberculosis TBL identified in patients with chronic inflammatory bowel disease candidates for anti-TNFα therapy in our study was 24.1%, detected by the Quantiferon Gold IT® test. Factors influencing the results of the t…
Muhammad Irshad, Shahzeen Irshad
…vity (83%) and 100% specificity for detecting Mycobacterium tuberculosis from fresh ulcer base biopsy samples, offering an alternative to conventional methods like acid-fast bacillus staining, TB-PCR, and histopathological examination. Given the diagnostic challenges in tuberculo…
Lijiao Chen, Lingke Yuan, Tingting Sun, Ruiqing Liu, Qing Huang, et al.
Abstract Background Tuberculosis is a chronic infectious disease caused by mycobacterium tuberculosis (MTB) and is the ninth leading cause of death worldwide. It is still difficult to distinguish active TB from latent TB ,so it is very important for individualized management and …
E. M. Bogorodskaya, В. И. Литвинов
…erature review briefly describes the main aspects of latent tuberculosis infection and the place of tuberculosis infection among various variants of the course of tuberculosis. Latent tuberculosis infection is one of the main problems of phthisiology. Today we have made significa…
Owusu W, van Vliet AHM, Riddell NE, Stewart G, Akwani WC, et al.
In low-resource settings with high tuberculosis (TB) burdens, lack of rapid diagnostic methods for detection and differentiation of Mycobacterium tuberculosis complex (MTBC) is a major challenge affecting TB management. This study utilized comparative genomic analyses of MTBC lin…
Alison Smith, Russell R. Kempker, Liya Wassie, Kidist Bobosha, Azhar Nizam, et al.
…amines the association between diabetes mellitus and latent tuberculosis infection among a cohort of household contacts exposed to active tuberculosis in Ethiopia, focusing attention on the need for further translational research to determine the mechanisms of susceptibility to M…
Chen L, Yuan L, Sun T, Liu R, Huang Q, et al.
Background Tuberculosis is a chronic infectious disease caused by mycobacterium tuberculosis (MTB) and is the ninth leading cause of death worldwide. It is still difficult to distinguish active TB from latent TB,but it is very important for individualized management and treatment…
Mariana S. Sousa, Inês Ladeira, Carlos Fernandes, Ana Ponte, Adélia Rodrigues, et al.
Portugal is one of the countries with the highest tuberculosis burden in the European Union, with a reporting rate in the North region registered in 2016 of 21.6 cases per 100000 inhabitants. Anti-TNF can increase up to five times the reactivation of tuberculosis in patients with…
Giovanni Battista Migliori, Ong C, Linda Petrone, Lia D’Ambrosio, Rosella Centis, et al.
Latent tuberculosis infection was the term traditionally used to indicate tuberculosis (TB) infection. This term was used to define “a state of persistent immune response to stimulation by Mycobacterium tuberculosis antigens through tests such as the tuberculin skin test (TST) or…
Flynn AG, Aiona K, Haas MK, Reves R, Belknap R
Although rare, subclinical tuberculosis disease can be missed during evaluations for latent tuberculosis infection, and can manifest with symptoms during latent tuberculosis treatment. Among over 8000 patients treated for latent tuberculosis we found no evidence of acquired drug …
Y. Nakano, Kenta Yamada, Koji Suzuki, Motoko Yasutomi, Motohiro Takeuchi, et al.
Pancreatic tuberculosis (TB) is a rare form of extrapulmonary TB.1 We present a case of pancreatic TB requiring differentiation from pancreatic neoplasms. A 13-year-old boy born in the Philippines presented with fever and back pain lasting 6 days. While living in the Philippines,…
Carvalho I, Goletti D, Manga S, Silva DR, Manissero D, et al.
Tuberculosis (TB) is a major cause of childhood morbidity and mortality worldwide. The aim of this review is to describe the management of the child with TB and latent tuberculosis infection (LTBI). To develop this article, a working group reviewed relevant epidemiological and ot…
Lu P, Xu J, Wang R, Gong X, Liu Q, et al.
… is recommended by the World Health Organization for latent tuberculosis infection (LTBI). However, it is still unknown how the EC skin test performs in students during a school tuberculosis outbreak. Methods We conducted an epidemiological investigation to assess the performance…
Ye L, Cao Y, Fu Y, Tian C, Cao Q
Background Discriminating Crohn's disease (CD) with latent tuberculosis infection (LTBI) from intestinal tuberculosis (ITB) in tuberculosis-endemic regions remains challenging. Aim To assess whether targeted next-generation sequencing (tNGS) could be an efficient method for ITB d…
Della Bella C, Spinicci M, Grassi A, Bartalesi F, Benagiano M, et al.
Background Tuberculosis (TB) still is a major worldwide health problem, with 10.4 million new cases in 2016. Only 5-15% of people infected with M. tuberculosis develop TB disease while others remain latently infected (LTBI) during their lifetime. Thus, the absence of tests able t…
Derliyana Irwan Badarudin, Muhammad Nasrum Massi, Ahyar, Arif Santoso, Burhanuddin Bahar, et al.
…Immunosorbent Assay (ELISA). The samples in this study were tuberculosis and latent after 2 months of treatment, the samples used were 30 samples, statistic tests were normality tests with Shapiro Wilk and Independent sample tests. The results of the research that has been done, …
S Praveen Raj Dr. Anitha S Menon
…cemasks is likely to reduce the spread of <em>Mycobacterium tuberculosis (MTB)</em>. However, there is an anticipated net negative effect of COVID-19 on TB control, including an increase in the number of TB cases, death and the proportion of drug- resistant TB. Here, we present s…
Smith A, Kempker R, Wassie L, Bobosha K, Nizam A, et al.
…amines the association between diabetes mellitus and latent tuberculosis infection among a cohort of household contacts exposed to active tuberculosis in Ethiopia, focusing attention on the need for further translational research to determine the mechanisms of susceptibility to M…
Liu Y, Zhang L, Chen Y, Ruan G, Liu Y, et al.
Background The population with latent tuberculosis infection (LTBI) represents a potential pool of patients with active tuberculosis (ATB). T-SPOT.TB is an important test tool for screening LTBI. Owing to the large population of LTBI patients in China, it is necessary to identify…
Justen T Despain, John L Kiley, Mary B Ford
**INTRODUCTION:** Tuberculosis (TB) causes significant morbidity and mortality worldwide. Diagnosing TB in service members can be a challenge given the overall low incidence but increased risk of exposure that accompanies military travel, training and activities. Here we describe…
Luo D, Yang BY, Qin K, Shi CY, Wei NS, et al.
Purpose Distinguishing latent tuberculosis infection (LTBI) from active tuberculosis (ATB) is important to control the prevalence of tuberculosis; however, there is currently no effective method. The aim of this study was to discover specific metabolites through fecal untargeted …
Lee JY, Kim BJ, Koo HK, Kim J, Kim JM, et al.
Tuberculosis remains a major public health problem. Conventional tests are inadequate to distinguish between active tuberculosis (ATB) and latent tuberculosis infection (LTBI). We measured antibody responses to Mycobacterium tuberculosis antigens ( Mycobacterium tuberculosis chor…
Tang W, Leonhardt L, Pervez A, Sarvepalli S
The reactivation of latent tuberculosis occurs when a patient living with Mycobacterium tuberculosis enters a state where the immune system is suppressed. Since early 2021, the standard of care has been to provide corticosteroids in patients with COVID-19 infection in hospitalize…