Showing 126–150 of 200 documents
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Berrocal-Almanza LC, Harris R, Lalor MK, Muzyamba MC, Were J, et al.
… Evaluating interventions that might lead to a reduction in tuberculosis in high-income countries with a low incidence of the disease is key to accelerate progress towards its elimination. In such countries, migrants are known to contribute a large proportion of tuberculosis case…
Nilesh NamdeoGhule, Geeta Shiroor
The high incidence of Tuberculosis is a cause for concern and a huge threat to public health globally. The delays in case detection, diagnosis, health seeking, and non-adherence to treatment are some of the reason for the high Tuberculosis burden globally. In many tuberculosis Ce…
Menzies NA, Quaife M, Allwood BW, Byrne AL, Coussens AK, et al.
Background Many individuals who survive tuberculosis disease face ongoing disability and elevated mortality risks. However, the impact of post-tuberculosis sequelae is generally omitted from policy analyses and disease burden estimates. We therefore estimated the global burden of…
Ogwang MO, Imbuga M, Ngugi C, Mutharia L, Magoma G, et al.
Introduction Globally anti-tuberculosis drug resistance is one of the major challenges affecting control and prevention of tuberculosis. Kenya is ranked among 30 high burden TB countries globally. However, there is scanty information on second line antituberculosis drug resistanc…
Kim JW, Bowman K, Nazareth J, Lee J, Woltmann G, et al.
Background Incipient tuberculosis, a progressive state of Mycobacterium tuberculosis infection with an increased risk of developing into tuberculosis disease, remains poorly characterised. Animal models suggest an association of progressive infection with bacteraemia. Circulating…
Leonardo Martínez, Neus Altet, F Boulahbal, Joan A. Caylà, Tsira Chakhaia, et al.
…t Objective To evaluate the impact of isoniazid on incident tuberculosis in household contacts of MDR tuberculosis cases. Design Systematic review and individual-participant meta-analysis. Data sources MEDLINE, Web of Science, BIOSIS, and Embase without language restrictions for …
da Costa FBP, Nicol MP, Botha M, Workman L, Arcêncio RA, et al.
Background Paediatric tuberculosis leads to more than 200 000 deaths annually. We aimed to investigate the incidence of Mycobacterium tuberculosis infection and tuberculosis disease in the first decade of life in the Drakenstein Child Health Study (DCHS), a South African cohort i…
Fernanda Bruzadelli Paulino da Costa, Mark P. Nicol, Maresa Botha, Lesley Workman, Ricardo Alexandre Arcêncio, et al.
BACKGROUND: Paediatric tuberculosis leads to more than 200 000 deaths annually. We aimed to investigate the incidence of Mycobacterium tuberculosis infection and tuberculosis disease in the first decade of life in the Drakenstein Child Health Study (DCHS), a South African cohort …
Marcy O, Goyet S, Borand L, Msellati P, Ung V, et al.
Background There is no gold standard for tuberculosis diagnosis in children. Clinical Case Definitions for Classification of Intrathoracic Tuberculosis in Children were proposed by international experts in 2012 and updated in 2015. We aimed to compare the 2012 and 2015 Clinical C…
Saunders MJ, Wingfield T, Datta S, Montoya R, Ramos E, et al.
…eness of social protection and biomedical interventions for tuberculosis-affected households might be improved by risk stratification. We therefore derived and externally validated a household-level risk score to predict tuberculosis among contacts of patients with tuberculosis. …
K Monisha, Siddlingappa Hugara, K M Nanditha
**BACKGROUND:** National Tuberculosis Elimination Programme focuses more on open (pulmonary) cases of tuberculosis. In addition to pulmonary tuberculosis, extrapulmonary tuberculosis cases also contribute to the tuberculosis burden and spread of infection among household contacts…
Hu SS, Wei QC, Wu Y, Li XN, Liu FJ, et al.
Background Extrapulmonary tuberculosis (TB) is a relatively rare form of tuberculosis infection, accounting for approximately 15% of all tuberculosis infections. Lymph nodes are the most commonly affected sites, while involvement of the parotid gland is extremely rare. Case prese…
Engel N, Ochodo EA, Karanja PW, Schmidt BM, Janssen R, et al.
…kground Programmes that introduce rapid molecular tests for tuberculosis and tuberculosis drug resistance aim to bring tests closer to the community, and thereby cut delay in diagnosis, ensure early treatment, and improve health outcomes, as well as overcome problems with poor la…
Shasha Hu, Qingzhu Wei, Yu Wu, Xin-Nian Li, Fujin Liu, et al.
BACKGROUND: Extrapulmonary tuberculosis (TB) is a relatively rare form of tuberculosis infection, accounting for approximately 15% of all tuberculosis infections. Lymph nodes are the most commonly affected sites, while involvement of the parotid gland is extremely rare. CASE PRES…
D. M. Kutuzova, T.E. Tyulkova, Valentina Tinkova
…enting with limited pulmonary damage, who were monitored in tuberculosis care institutions. Patients and Methods: a retrospective study was conducted based on medical record analysis of patients observed for tuberculosis in an antituberculosis dispensary during 2020–2021. Initial…
Oo MM, Tassanakijpanich N, Phyu MH, Safira N, Kandel S, et al.
Background The comorbid presence of tuberculosis and diabetes mellitus has become an increasingly important public health threat to the prevention and control of both diseases. Thus, household contact investigation may serve a dual purpose of screening for both tuberculosis and d…
Gebremariam G, Kiros M, Hagos S, Hadush H, Gebremichael A, et al.
Background Tuberculosis (TB) is a major public health concern in the developing countries. Moreover, the emergence of multidrug-resistant tuberculosis is challenging. However, there are no organized data on the trends of pulmonary tuberculosis and rifampicin-resistant Mycobacteri…
Ali MM, Weldegebreal F, Kabew G, Urgesa K
Background Multi-drug resistant Mycobacterium tuberculosis is a growing public health problem in developing countries including Somalia. Although, the prevalence of multi-drug resistant tuberculosis among new and retreated cases is high, data on GeneXpert- Mycobacterium tuberculo…
JAYA JAIN, Deepti Shrivastava
…CTION •There exists a lot of diagnostic dilemma for genital tuberculosis in the available literature No single test is found confirmatory except for wet culture and histopathological positivity which may become paucibacillary extrapulmonary sites and time consuming too. •Polymera…
Belay M, Tulu B, Younis S, Jolliffe DA, Tayachew D, et al.
…rface marker have been posited as a niche for Mycobacterium tuberculosis complex bacilli during latent tuberculosis infection. Our aim was to determine whether M tuberculosis complex DNA is detectable in CD34-positive peripheral blood mononuclear cells (PBMCs) isolated from asymp…
Alrajhi AA, Alotaibi J, Alghamdi AM, Almanea H, AlSebayel M, et al.
Objectives Mycobacterium tuberculosis DNA has been detected in multiple organs in people without active tuberculosis or a history of tuberculosis. Molecular testing for metabolic activity has suggested that M tuberculosis DNA represents viable bacilli. Whether transplanted organs…
Visensius Krisdianilo, Vincentia Ade Rizky, Saadah Siregar, Asvia Rahayu
Background: Mycobacterium tuberculosis is known as a highly pathogenic bacterium. These bacteria are aerobic in shape like rods and have resistance to acids. This bacteria can cause tuberculosis (TB). TB disease has been widely recognized as a cause of death which is quite high i…
Cosmas Kenan Onah, Benedict Ndubueze Azuogu, Edmund Ndudi Ossai, Adaoha Pearl Agu, Victoria Chioma Azuogu, et al.
Abstract Background: A major constraint to tuberculosis control is low case finding with under-reporting to national authorities. Evidence shows that Patent Medicine Dealers are first port of call for most people with symptoms of tuberculosis, yet there is poor referral of such c…
Onah CK, Azuogu BN, Ossai EN, Agu AP, Azuogu VC, et al.
Background A major constraint to tuberculosis control is low case finding with under-reporting to national authorities. Evidence shows that Patent Medicine Dealers are first port of call for most people with symptoms of tuberculosis, yet there is poor referral of such clients to …
E. M. Bogorodskaya, E. M. Belilovsky, L. B. Ayusheeva, E. N. Posadskaya
…tients with HIV infection is of the leading risk groups for tuberculosis. According to WHO, the presence of HIV infection increases the likelihood of developing tuberculosis by 26 times and is the second factor in the world after malnutrition that affects the number of cases of t…