Showing 101–125 of 200 documents
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Herikurniawan Herikurniawan, Joanna Audrey, Mira Yulianti, N Indira, Cleopas Martin Rumende
Tuberculosis (TB) has become one of the global burdens of disease, with increasing morbidity and mortality every year. Tuberculosis can affect not only the lungs but also the extrapulmonary organs. The prevalence of drug-resistant tuberculosis (DR-TB) is rising and has caused a h…
Shanbag N, Haseeb M, Engade M, Siddiqui MS, Badaam KM, et al.
Background The prevalence of tuberculosis (TB) disease among household contacts of adult TB patients is very high. Contact screening and isoniazid preventive therapy (IPT) are recommended for household contacts, but their uptake by families and implementation by the national TB p…
Xichao Ou, Peilei Hu, Xundi Bao, Zhou Liu, Chong Teng, et al.
…ication and testing (AutoSAT) method in suspected pulmonary tuberculosis (PTB) and extrapulmonary tuberculosis (EPTB) by comparing with Xpert MTB/RIF (Xpert) method against the composite reference standard. **METHOD:** Patients with suspected PTB or EPTB were enrolled consecutiv…
Addo SO, Abrahams AOD, Mensah GI, Mawuli BA, Mosi L, et al.
…ity of immunohistochemistry (IHC) using anti- Mycobacterium tuberculosis antibody (ab905) for detecting the presence of mycobacterial antigens in archived formalin-fixed paraffin-embedded (FFPE) tissues. Methods FFPE tissues [surgical biopsies (n = 32) and post-mortem tissues (n …
International Journal of Medical Science and Advanced Clinical Research (IJMACR)
Abstract Introduction: Accurate and timely tuberculosis diagnosis is the primary step for initiating effective treatment. The colour plate agar-based culture test (TB-CX test) is a low cost, simple to use, detects Mycobacterium tuberculosis faster. The study conducted to compare …
Aylin Var, Yusuf Uysal, Mehmet Kuruş, Yağmur Seda Yeşiltaş, Uğur Bozlar, et al.
PURPOSE: Orbital/periorbital tuberculosis (TB) is an uncommon manifestation of extrapulmonary TB, presenting diagnostic challenges due to its varied clinical features that can mimic other diseases. This report aims to present a rare case of periorbital TB in a young man. METHODS:…
International Journal of Medical Science and Advanced Clinical Research (IJMACR)
Abstract Introduction: Accurate and timely tuberculosis diagnosis is the primary step for initiating effective treatment. The colour plate agar-based culture test (TB-CX test) is a low cost, simple to use, detects Mycobacterium tuberculosis faster. The study conducted to compare …
Scherer J, Mukasa SL, Wolmarans K, Guler R, Kotze T, et al.
Background Tuberculosis (TB) is caused by Mycobacterium tuberculosis (Mtb) and typically infects the lungs. However, extrapulmonary forms of TB can be found in approximately 20% of cases. It is suggested, that up to 10% of extrapulmonary TB affects the musculoskeletal system, in …
Ayu Rizky Widowati, I Wayan Agung Indrawan, Rezki Tantular
Introduction: Female Genital Tuberculosis (FGTB) is a rare but serious form of extrapulmonary tuberculosis that significantly impacts female reproductive health. It accounts for 15–20% of extrapulmonary TB cases and is found in 5–10% of infertile women. Diagnosis is often delayed…
Sibandze DB, Magazi BT, Malinga LA, Maningi NE, Shey BA, et al.
… There is a general dearth of information on extrapulmonary tuberculosis (EPTB). Here, we investigated Mycobacterium tuberculosis (Mtb) drug resistance and transmission patterns in EPTB patients treated in the Tshwane metropolitan area, in South Africa. Methods Consecutive Mtb cu…
Var A, Uysal Y, Kuruş M, Yeşiltaş YS, Bozlar U, et al.
Purpose Orbital/periorbital tuberculosis (TB) is an uncommon manifestation of extrapulmonary TB, presenting diagnostic challenges due to its varied clinical features that can mimic other diseases. This report aims to present a rare case of periorbital TB in a young man. Methods C…
Sharma K, Sharma M, Ayyadurai N, Dogra M, Sharma A, et al.
…IF Ultra (Ultra) was evaluated for the first time on Ocular tuberculosis (OTB) samples and compared with Xpert. Methods Seventy five vitreous fluid samples (3 confirmed OTB, 47 clinically suspected OTB, and 25 controls) were subjected to Ultra, Xpert and Multiplex-PCR and compare…
Faksri K, Xia E, Ong RT, Tan JH, Nonghanphithak D, et al.
Tuberculous meningitis (TBM) is a severe form of tuberculosis with a high mortality rate. The factors associated with TBM pathogenesis are still unclear. Using comparative whole-genome sequence analysis we compared Mycobacterium tuberculosis (Mtb) isolates from cerebrospinal flui…
S Sinha, A Ajayababu, R Titiyal, A Sinha, P R Mohapatra, et al.
Abstract Background Extrapulmonary tuberculosis (EPTB) constituting approximately one-fifth of the overall burden of tuberculosis (TB), is challenge both in terms of diagnosis due to lower rates of microbiological positivity and for treatment in terms of drug penetration, duratio…
Doctor Busizwe Sibandze, Beki Themba Magazi, Lesibana Anthony Malinga, Nontuthuko Excellent Maningi, Bong Akee Shey, et al.
… There is a general dearth of information on extrapulmonary tuberculosis (EPTB). We investigated Mycobacterium tuberculosis (Mtb) drug resistance and transmission patterns in EPTB patients treated in the Tshwane metropolitan, South Africa. Methods Consecutive Mtb culture-positive…
Kim M, Lee JH, Lee HN, Park DJ, Lee EJ
Tuberculosis (TB), an infectious disease caused by Mycobacterium tuberculosis (MTB), can affect the lungs (pulmonary TB) as well as other sites (extrapulmonary TB). Nasopharyngeal tuberculosis (NPTB) is a rare type of extrapulmonary TB. Since NPTB has nonspecific clinical present…
Kaur K, Sharma S, Abhishek S, Kaur P, Saini UC, et al.
Objectives Bone tuberculosis (TB) is the third most common types of extrapulmonary tuberculosis. It is critical to understand mycobacterial adaptive strategies within bone lesions to identify mycobacterial factors that may have role in disease pathogenesis. Methods Whole genome m…
Kaur K, Laal S, Ryndak MB
Introduction . Intraocular tuberculosis (IOTB) is a significant cause of visual morbidity in tuberculosis (TB)-endemic countries. Although Mycobacterium tuberculosis ( M. tb ) has been detected in both the retinal pigment epithelial (RPE) cells and in the intraocular fluid (IOF) …
Enes Dalmanoğlu
…neous involvement is a relatively uncommon manifestation of tuberculosis. Cutaneous lesions account for less than 2 percent of all extrapulmonary manifestations. Due to the paucibacillary nature of the lesions, there is a potential for misdiagnosis, which could result in the chro…
Shreya Dubey, RV Singh, Bhavana Gupta, Anju Nayak, Ajay Rai, et al.
Tuberculosis has been declared as global emergency by WHO as about 85 per cent of all tuberculosis cases occur in WHO region of South East Asia (34%), Africa (31%) and western pacific (20%). The disease is accountable for more deaths throughout the world than any other bacterial …
Human Sciences Research Council
…mmunopathology occurs in human immunodeficiency virus (HIV)/tuberculosis (TB) coinfection, but the underlying molecular mechanisms are not well-defined. Excessive matrix metalloproteinase (MMP) activity is emerging as a key process but has not been systematically studied in HIV-a…
Payal Gami Vinit Patel
… abscess of chest wall accounts for 1-4% of musculoskeletal tuberculosis which in case accounts for 1-2% of all types of tuberculosis. It is a rare form of extrapulmonary tuberculosis. It is rare in a immunocompetent patients to have chest wall abscess with concomitant tubercular…
Şahin Mavi EA, Akdemir MÇ, Akin AE, Uyaroğlu OA, Köksal D
Tuberculosis (TB) is an airborne infectious disease caused by Mycobacterium tuberculosis (MTB). Although it typically affects the lungs (pulmonary TB), one-fifth of TB cases present as extrapulmonary TB. The diagnosis of extrapulmonary TB is often overlooked due to its atypical c…
Felisitas Farica Sutantoyo, Paulus Sugianto
Background/aim. Mycobacterium tuberculosis (M. tuberculosis) infection can cause pulmonary and extrapulmonary tuberculosis (TB), resulted from hematogenous or lymphatic dissemination of the bacteria. Disseminated TB is characterized by the presence of two or more non-contiguous s…
Li H, Long Y, Shao F, Lan X
Extrapulmonary tuberculosis could involve multiple organs. However, thymic tuberculosis is relatively rare. We report a 21-year-old man who was referred for an F-FDG PET/CT imaging to assess his newly detected pulmonary nodule. The images showed the pulmonary nodule had minimal a…