Showing 101–125 of 200 documents
Sorted by hybrid relevance (keyword + semantic via RRF)
Olivia Kamoen, Kenan Bosco, Liberius Libent, Colman E. Assenga, Eli Mkwizu, et al.
In sub-Saharan Africa (SSA) central nervous system (CNS) infections in patients with HIV/AIDS are a major cause of HIV-related mortality and morbidity. We describe a patient with a paraparesis after start of tuberculosis (TB) treatment. The patient had stage IV HIV and was not on…
Saavedra Cervera B, López MG, Chiner-Oms Á, García AM, Cancino-Muñoz I, et al.
Genomic studies of the Mycobacterium tuberculosis complex (MTBC) might shed light on the dynamics of its transmission, especially in high-burden settings, where recent outbreaks are embedded in the complex natural history of the disease. To this end, we conducted a 1 year prospec…
Modongo C, Wang Q, Dima M, Matsiri O, Kgwaadira B, et al.
Background Dolutegravir (DTG) has recently been recommended as a preferred first-line regimen for the treatment of new and treatment-experienced HIV-infected patients. However, potential drug interactions between DTG and rifampicin remain a clinical and public health concern. Met…
LaCourse SM, Seko E, Wood R, Bundi W, Ouma GS, et al.
Objective We evaluated diagnostic performance of oral swab analysis (OSA) for tuberculosis (TB) in a high HIV/TB burden setting in Kenya. Methods In this cross-sectional study, buccal swabs and sputum were collected from 100 participants with suspected TB in outpatient clinics in…
Tapiwa Kumwenda, Veronica Phiri, Kelvin Rambik, Bianca Sossen, Tamiwe Tomoka, et al.
**BACKGROUND:** Enlarged lymph nodes (LN) pose diagnostic challenges for people with HIV (PWH). While tuberculosis (TB) is a common cause in low-income settings, lymphomas and Kaposi's sarcoma must also be considered. Ultrasound and symptoms cannot distinguish between these condi…
Wang DM, Li QF, Zhu M, Xu YH, Liao Y
…extrapulmonary tuberculosis/human immunodeficiency virus (EPTB/HIV) co-infection patients, especially the resistance profile of culture-confirmed EPTB. The purpose of our study was to analyse the clinical characteristics, common sites and drug resistance profile of culture-confir…
Mishkin K, Alaei K, Alikeyeva E, Paynter C, Aringazina A, et al.
Objectives Drug-resistant tuberculosis (TB) poses a serious threat to public health in Kazakhstan. This paper presents findings related to TB treatment outcome and drug resistance status among people co-infected with human immunodeficiency virus (HIV) and TB in Kazakhstan. Method…
Fielies ML, Walker IS
Aneurysmal dilatation secondary to HIV vasculitis is well described being more common in patients under 45 years of age with advanced stage HIV infection (CD4 < 200 cells/µl). Tuberculous meningitis is far more common than previously anticipated with centres in Cape Town publishi…
Mchunu NN, Mwambi HG, Rizopoulos D, Reddy T, Yende-Zuma N
Background The association structure linking the longitudinal and survival sub-models is of fundamental importance in the joint modeling framework and the choice of this structure should be made based on the clinical background of the study. However, this information may not alwa…
Torpey K, Agyei-Nkansah A, Ogyiri L, Forson A, Lartey M, et al.
Tuberculosis (TB) and HIV are strongly linked. There is a 19 times increased risk of developing active TB in people living with HIV than in HIV-negative people with Sub-Saharan Africa being the hardest hit region. According to the WHO, 1.3 million people died from TB, and an addi…
Zeleke A, Misiker B, Yesuf TA
Objectives Anti-tuberculosis drug-induced hepatotoxicity is a common serious adverse drug reaction. This study intended to determine the prevalence and associated factors of drug-induced hepatotoxicity among tuberculosis and human immunodeficiency virus co-infected patients in De…
Belén Saavedra, Mariana G. López, Álvaro Chiner‐Oms, Ana María García García, Irving Cancino‐Muñoz, et al.
Abstract Genomic studies of Mycobacterium tuberculosis complex (MTBC) might shed light on the dynamics of its transmission, especially in high-burden settings, where recent outbreaks are embedded in the complex natural history of the disease. We applied Whole-genome sequencing (W…
Lwin N, Boyle M, Davis JS
Corticosteroids are the mainstay of therapy for immune reconstitution inflammatory syndrome (IRIS). However, little is known about how to treat IRIS unresponsive to steroids. We report a patient with HIV-TB coinfection who was unresponsive to first prednisolone and then inflixima…
Sharan R, Bucşan AN, Ganatra S, Paiardini M, Mohan M, et al.
HIV co-infection is the most critical risk factor for the reactivation of latent tuberculosis (TB) infection (LTBI). While CD4 + T cell depletion has been considered the major cause of HIV-induced reactivation of LTBI, recent work in macaques co-infected with Mycobacterium tuberc…
Maji D, Agarwal U, Kumar L, V V, Sharma A
The risk of death in HIV-TB coinfected individuals is far greater than in HIV-only patients. It is critical to provide timely and appropriate therapy in HIV-TB coinfected patients in order to reduce morbidity and mortality. The purpose of this study was to evaluate the clinical p…
Adeloye Adewale Idowu, Ayinde Abayomi Oluwasegun, Ohue Michael, Tope Gloria Olatunde-Aiyedun, Ogunode Niyi Jacob
…ive studies focusing on the distributions and correlates of TB/HIV co-infections among Patients attending TB clinics in Ibadan are lacking in the literature. The objective of this study was to determine the prevalence and correlates of TB/HIV co-infection among patients suspected…
Tuberculosis in combination with HIV infection (TB/HIV) poses a threat to the TB epidemic well-being. Pur-pose: to study trends in the prevalence of tuberculosis (TB), including TB/HIV, in Russia as a whole and by re-gions. Methods: official statistics were used. The list of regi…
Agballa Mébiny-Essoh Tchalla Abalo, Essona Matatom Akara, Toyi Tchamdja, Bokoulmé Haienga, Kassouta N’tapi, et al.
…fection with Tuberculosis and Human Immunodeficiency Virus (TB/HIV) is highly lethal and Africa hosts 74% of cases. In Togo, the prevalence of TB/HIV co-infection was 22% in 2016 with a 42% mortality among the TB/HIV co-infected cases. There is limited data on TB/HIV co-infection…
Darya Ebrahimi Moghaddam, Javid Sadri Nahand, Farah Bokharaei-Salim, Tahereh Donyavi, Fatemeh Ahmadi
… in distinguishing TB monoinfection, HIV monoinfection, and TB/HIV co-infection remains unclear. In this study, we examined the expression of miR-155, miR-29a, and lncRNAs (lncRNA-COX2, lncRNA-NEAT1, lncRNA-GAS5) by qRT-PCR in peripheral blood mononuclear cells (PBMCs) from 95 pa…
Lelisho ME, Teshale BM, Tareke SA, Hassen SS, Andargie SA, et al.
…y was to identify factors associated with survival rates of TB/HIV co-infected patients using survival models. Methods A retrospective study was conducted on TB/HIV co-infected adult patients registered and under follow-up at Tepi General Hospital (TGH) and Mizan-Tepi University …
Martino RJ, Chirenda J, Mujuru HA, Ye W, Yang Z
…ntify patient characteristics significantly associated with TB/HIV coinfection. Of the 13,802 TB cases analyzed, 9,725 (70.5%) were HIV positive. A significantly higher odds of having TB/HIV coinfection diagnosis was found among females, patients aged 25-64 years, previously trea…
Hudson M, Rutherford GW, Weiser S, Fair E
…and private healthcare providers to maximize integration of TB/HIV services and minimize costs. We systematically reviewed published models of public-private sector diagnostic and referral services for TB/HIV co-infected patients. Methods We searched PubMed, the Cochrane Central …
Dlatu N, Longo-Mbenza B, Apalata T
… A Likert scale was used to assess the perceived quality of TB/HIV integration. Regression models and canonical discriminant analyses were used to explore the associations between the perceived quality of TB and HIV integrated service delivery and independent predictors of intere…
Ngari MM, Rashid MA, Sanga D, Mathenge H, Agoro O, et al.
…nt outcomes, there is paucity of data on changing trends of TB/HIV co-infection and their treatment outcomes. This study aims to estimate the burden of TB/HIV co-infection over time, describe the treatment available to TB/HIV patients and estimate the effect of TB/HIV co-infectio…
Benjamin Momo Kadia, Noah Fongwen, Christian Akem Dimala, Victoria Simms
…(HIV) in sub-Saharan Africa (SSA), TB treatment outcomes in TB/HIV co-infected patients in the region remain sub-optimal.<bold>Objective: </bold>To summarize the available evidence on the association between integrated TB/HIV treatment and TB treatment outcomes specifically, succ…