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Shivalli S, Hondappagol A, Akshaya KM, Nirgude A, Varun N, et al.
…This is a pragmatic, prospective, non-randomised controlled trial in two pairs of RNTCP Designated Microscopy Centres (located at secondary and primary healthcare facilities) of Dakshina Kannada district, India. Presumptive pulmonary TB patients aged ≥18 years will be included. W…
Ashwin Karnan, Ulhas Jadhav, Babaji Ghewade, Vivek Alone
…y with slightly better adherence in the shorter regimen. **CLINICAL TRIAL REGISTRATION:** The study was registered in the Clinical Trials Registry-India (Indian Council of Medical Research-National Institute of Medical Statistics), https://ctri.nic.in/, CTRI registration number …
Tadesse AW, Mohammed Z, Foster N, Quaife M, McQuaid CF, et al.
…gn We will conduct a pragmatic three-arm cluster-randomised trial with 78 health facilities in two regions in Ethiopia. Facilities are randomised (1:1:1) to either of the two intervention arms or standard of care. Adults aged ≥ 18 years with drug-sensitive (DS) pulmonary TB are e…
Jahnke N, Waters V, Ratjen F, Smith S, Hambleton IR, et al.
…(CF). Search methods We searched Cochrane's Cystic Fibrosis Trials Register, online databases (MEDLINE, Embase and PubMed) and online trials registries (www. Clinicaltrials gov and the World Health Organization International Clinical Trials Registry). We also searched the referen…
Geetanjali Chander, Nishi Suryavanshi, Nikhil Gupte, Gauri Dhumal, Shatabdi Bagchi, et al.
…outcomes. This paper describes the protocol for HATHI,ybrid trial forlcohol reduction among people withB andIV inndia, a Hybrid Type 1 effectiveness-implementation trial, that tests if a behavioral intervention integrated into TB and HIV treatment, compared to usual care, results…
Kay AW, González Fernández L, Takwoingi Y, Eisenhut M, Detjen AK, et al.
…dered age, disease severity, smear-test status, HIV status, clinical setting, specimen type, high tuberculosis burden, and high tuberculosis/HIV burden - For detection of rifampicin resistance, we considered multi-drug-resistant tuberculosis burden • To compare multiple Xpert MTB…
Karikalan Nagaraj, Bella Devaleenal Daniel, Chandra Suresh, Dhanalakshmi Angamuthu, Shobana Palanisamy, et al.
…based interventions under the National TB program of India. Clinical trial registration The study has been registered in the Clinical Trial Registry of India CTRI/2024/05/066847.
Yadav B, Rai A, Mundada PS, Singhal R, Rao BCS, et al.
…tions in cases suffering with long term effects of COVID 19 TRIAL DESIGN: Multi-centric, randomized, controlled, parallel group, open-label, exploratory study. The study duration is 9 months and the intervention period is 90 days from the day of enrolment of the participant. Part…
Kohei Fujita, Yutaka Ito, Yuki Yamamoto, Osamu Kanai, Takuma Imakita, et al.
…ormer had more localized lung inflammation than the latter. Trial registration : This trial was prospectively registered in the Clinical Trials Registry (UMIN 000027652).
Kohei Fujita, Yutaka Ito, Yuki Yamamoto, Osamu Kanai, Takuma Imakita, et al.
…ormer had more localized lung inflammation than the latter. TRIAL REGISTRATION: This trial was prospectively registered in the Clinical Trials Registry (UMIN 000027652).
Sumari-de Boer M, Pima FM, Ngowi KM, Chelangwa GM, Mtesha BA, et al.
…reatment outcome. We propose a pragmatic cluster randomized trial to investigate the effectiveness of evriMED with reminder cues and tailored feedback on adherence to TB treatment in Kilimanjaro, Tanzania. Methods/design We will create clusters in Kilimanjaro based on level of he…
Khan S, Shahzadi A
… search of PubMed, the Cochrane Central Register of Control Trials, Science Direct, and Clinical Trials Registry (ClinicalTrials.gov), encompassing the period between 2000 and 2017, was conducted in accordance to PRISMA guidelines. Seven studies were identified. Collectively, the…
Steven Taylor, Kerry L. Ivey, Peter G. Gibson, Jodie L. Simpson, Geraint B. Rogers
… in adults with persistent symptomatic asthma in the AMAZES trial (Australian and New Zealand Clinical Trials Registry (ANZCTR), number 12609000197235) [1]. However, response to treatment was variable between participants and the characteristics of those who experience most clini…
Misra UK, Kumar M, Kalita J
…le-centre, open-label, parallel group randomized controlled trial was conducted from May 2017 to June 2019 in India. Treatment-naïve patients with TBM fulfilling the inclusion criteria were randomized to four drug ATT regimens (rifampicin, isoniazid, ethambutol and pyrazinamide) …
Gao L, Zhang H, Xin H, Liu J, Pan S, et al.
…rganization's End TB Strategy.In this randomised controlled trial (Chinese Clinical Trial Registry identifier ChiCTR-IOR-15007202), two short-course regimens with rifapentine plus isoniazid (a 3-month once-weekly regimen and a 2-month twice-weekly regimen) were initially designed…
Bhargava A, Bhargava M, Velayutham B, Thiruvengadam K, Watson B, et al.
…. We designed an open-label, field-based cluster randomised trial to assess the impact of nutritional supplementation (with food rations) on TB incidence in a group at higher risk of TB infection and disease, viz household contacts (HHC) of patients with microbiologically confirm…
Bao Y, Wang C, Xu H, Lai Y, Yan Y, et al.
…ior and quality of prevention and control for pulmonary TB. Trial registration Chinese Clinical Trial Registry ChiCTR2200055557; https://tinyurl.com/4ray3xnw.
Wenwen Sun, Zhengwei Dong, Yiming Zhou, Kunlong Xiong, Hongcheng Liu, et al.
…infection were detected at one time by mNGS. All mNGS-based clinical decisions were made within 2 days.Conclusions The mNGS could accurately and quickly detect fungi and mycobacteria in FFPE specimens from postoperative granuloma specimens and identify the pathogens to the specie…
Kumwichar P, Prappre T, Chongsuvivatwong V
… conversion rates in a 60-day cluster randomized controlled trial with patients with pulmonary tuberculosis (VOT: n=63 and DOT: n=65) with positive sputum acid-fast bacilli smears and 38 observers equally randomized into the VOT and DOT groups (19 observers per group and n=1-5 pa…
Kumwichar P, Chongsuvivatwong V, Prappre T
…se of TB treatment. Methods A cluster randomized controlled trial of pulmonary TB patients and their observers will be conducted over a 2-month period. This study will be conducted in the Hat Yai and Meuang Songkhla districts of Songkhla Province, Southern Thailand. A total of 38…
Zhenfan Wang, Xue Tian, Feng Yang, Lu Wang, Hao Li, et al.
…s under near-infrared imaging. The primary outcomes of this trial were the detection rate and background-tumour ratio of lung nodules, and the secondary objectives were time to search for nodules and operative time to nodules excision. RESULTS: A total of 50 pulmonary nodules in …
Xing XW, Zhang JT, Ma YB, He MW, Yao GE, et al.
…d in conjunction with conventional microbiological testing. Trial Registration: Chinese Clinical Trial Registry, ChiCTR1800020442.
He CX, Wu C, Zhang L, Jin HZ
…he need for routine TBI screening and preventive treatment. Trial registration Chinese Clinical Trial Registry, ChiCTR2100045823.
Chengyu Jiang, Xiaoqing Luo
…f-management may enhance treatment outcomes in patients. **TRIAL REGISTRATION:** Chinese Clinical Trial Registry, ChiCTR2500096661. Registered 27 January 2025; Retrospectively registered.
Leon N, Balakrishna Y, Hohlfeld A, Odendaal WA, Schmidt BM, et al.
…ods We searched the Cochrane Central Register of Controlled Trials (CENTRAL) in the Cochrane Library, MEDLINE Ovid and Embase Ovid in May 2019. We searched Global Health, Ovid and PsycInfo in April 2016. In January 2020 we searched for grey literature in the Grey Literature Repor…