Showing 51–74 of 74 documents
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Ogyiri L, Lartey M, Ojewale O, Adjei AA, Kwara A, et al.
…cy Virus (HIV) globally. Ghana as one of the 30 high burden TB/HIV countries has a high annual TB case-fatality rate of 10%. The study sought to assess the effect of HIV infection on TB treatment outcomes and assess the time to mortality after treatment onset. Methods We conducte…
Bizuneh FK, Bizuneh TK, Masresha SA, Kidie AA, Arage MW, et al.
…ite the effectiveness of antiretroviral therapy in reducing mortality from opportunistic infections among people living with HIV (PLHIV), tuberculosis (TB) continues to be a significant cause of death, accounting for over one-third of all deaths in this population. In Ethiopia, t…
Natália Rocha Almeida, Caio Azevedo Lima, Natália Lopes de Freitas, Fabiana Brandão
…, caused by Mycobacterium tuberculosis. In Brazil, the high mortality rate is identified precisely on the occasion of coinfection and it can actively lead to severe complications. This study aimed to analyze the treatment of multidrug-resistant tuberculosis in patients co-infecte…
Nhandara RBC, Ayele BT, Sigwadhi LN, Ozougwu LU, Nyasulu PS
…rculosis (TB) is one of the leading causes of morbidity and mortality among people living with HIV/AIDS. The growing burden of TB/HIV co-infection continues to strain the healthcare system due to association with long duration of treatment. This is a catalyst for poor adherence t…
Aisha Athman Katuga
…gh, especially among the HIV infected and the prevalence of TB/HIV co-infection was largely unknown, particularly in developing countries, including Uganda all but fuels the need for this study. To assess the prevalence and determinants of TB-HIV co-infection among HIV-positive p…
Avoka VA, Osei E
… a synergistic increase in their prevalence, morbidity, and mortality. In Ghana, 32% of TB cases were estimated to be coinfected with the human immunodeficiency virus and acquired immune deficiency syndrome (HIV/AIDS) epidemic HIV, with the highest number of coinfections in the V…
Lakoh S, Jiba DF, Adekanmbi O, Poveda E, Sahr F, et al.
…assess the diagnosis, treatment outcomes, and predictors of mortality in adult tuberculosis (TB) patients in an urban setting with a high HIV prevalence. Methods A retrospective study was conducted of adult TB patients aged ≥15 years who were treated at Connaught Hospital in Free…
Ruiz L, Maya MA, Rueda ZV, López L, Vélez LA
…on Tuberculosis (TB) is an important cause of morbidity and mortality in HIV patients. It is unknown if the advent of molecular diagnostic methods and a greater availability of antiretroviral therapy (ART) in our country have changed some characteristics of the TB/HIV co-infectio…
Kulkarni S, Endsley JJ, Lai Z, Bradley T, Sharan R
…atent TB infection (LTBI), worsening disease conditions and mortality. There is a lack of biomarkers of LTBI reactivation and/or immune-related transcriptional signatures to distinguish active TB from LTBI and predict TB reactivation upon HIV co-infection. Characterizing individu…
Omara G, Bwayo D, Mukunya D, Nantale R, Okia D, et al.
TB/HIV co-infection is associated with poorer treatment outcomes compared to TB alone. This study assessed the TB treatment success rate and its predictors among TB/HIV co-infected patients in East and North Eastern Uganda. A retrospective cohort design was used, involving 324 pa…
Onyango DO, Yuen CM, Masini E, Borgdorff MW
…ency virus (HIV) co-infection and identify risk factors for mortality during TB treatment. Study design We conducted a retrospective analysis of the Kenyan national TB program data for patients enrolled from 2013 through 2015. A total of 23 753 children aged less than 15 years we…
Darya Ebrahimi Moghaddam, Javid Sadri Nahand, Farah Bokharaei-Salim, Tahereh Donyavi, Fatemeh Ahmadi
…eficiency virus (HIV) co-infection remain leading causes of mortality, especially in source-limited settings where diagnostic challenges impede timely management. Non-coding RNAs (ncRNAs) are emerging as non-invasive biomarkers for infectious diseases due to their role in immune …
Osei E, Oppong S, Der J
… accelerate the declines in Tuberculosis (TB) incidence and mortality, there is the need for National Tuberculosis Programmes (NTPs) to monitor trends in key indicators across a geographical location and to provide reliable data for direct measurement of TB incidence and mortalit…
Saraceni V, Benzaken AS, Pereira GFM, Andrade KB, Oliveira PB, et al.
…) in reported AIDS cases, to compare the characteristics of TB/HIV subjects with those without TB and to evaluate survival with or without TB in Brazil. Methods The data source was the linked database between AIDS (2011-2014) and TB (2011-2014) databases from the Notifiable Disea…
Muhie NS
…ants that affecting bivariate hematological parameter among TB/HIV co-infected adults under TB/HIV treatment in university of Gondar comprehensive specialized hospital. Method The result of these study was conducted at university of Gondar comprehensive specialized hospital, Gond…
Tola A, Mishore KM, Ayele Y, Mekuria AN, Legese N
…poor treatment adherence, high TB recurrence rate, and high mortality risk. Our objective was to assess the outcomes of TB treatment and associated factors among TB-HIV co-infected patients in Harar town, Eastern part of Ethiopia, 2018. Methods A retrospective study was conducted…
Shaik J, Pillay M, Jeena P
…round Tuberculosis (TB) is one of the most common causes of mortality globally with a steady rise in paediatric cases in the past decade. Laboratory methods of diagnosing TB and monitoring response to treatment have limitations. Current research focuses on interrogating host- and…
Cho FN, Achidi EA, Enoh JE, Pallerla SR, Linh LTK, et al.
…d tuberculosis (TB) are major contributors to morbidity and mortality in sub-Saharan Africa including Cameroon. Pharmacogenetic variants could serve as predictors of drug-induced hepatotoxicity (DIH), in patients with TB co-infected with HIV. We evaluated the occurrence of DIH an…
Jacques Lukenze Tamuzi, Ley Muyaya Muyaya, Patrick Mbuesse
…ed 9th rank in the world and 2nd rank in Africa. TB and HIV coinfection is a major public health issue in the DRC as the percentage of people living with HIV/TB is increasing. However, the country lacks a high evidence study that may depict the overview of HIV/TB co-infection. We…
Berry KM, Rodriguez CA, Berhanu RH, Ismail N, Mvusi L, et al.
…cidence rate in South Africa but the greatest proportion of TB/HIV co-infection, with 68% of TB patients estimated to have HIV. TB treatment outcomes are well documented at the national and provincial level; however, knowledge gaps remain on how outcomes differ across detailed ag…
Gelaw YA, Williams G, Soares Magalhães RJ, Gilks CF, Assefa Y
HIV associated tuberculosis (TB) morbidity and mortality is a major concern in sub-Saharan Africa. Understanding the level of HIV infection among TB patients is vital for adequate response. We conducted a systematic review and meta-analysis to estimate the prevalence of HIV in TB…
Kevin Brown, Aaron Walsh, Anjali S Yennemadi, Dearbhla M Murphy, Sarah A Connolly, et al.
Tuberculosis (TB)-associated mortality remains disproportionately high among people living with HIV (PLWH), with macrophage dysfunction representing a key mechanism of impaired host defence against Mycobacterium tuberculosis (Mtb) infection. Macrophage metabolic switching has eme…
Dastagiri P, Dasari Vanisree, K. Parameswari, Hema Preethi. P, P. Neeraja
… a global prevalence with devastating morbidity and massive mortality, a signicant percentage of TB cases are Human immunodeciency virus (HIV) positive also. As the HIV epidemic is fuelling the global TB epidemic, the prevalence of the virus in TB patients is a sensitive indica…
Tiruneh F, Deyas Y
…sful in developed countries. However, in developing country TB/HIV co-infection remains perplexing among children on the treatment. The aim of this study was to investigate the impact of ART on the incidence of TB among Children infected with HIV in Southwest Ethiopia. A retrospe…