Showing 51–75 of 200 documents
Sorted by hybrid relevance (keyword + semantic via RRF)
Headriawan A, Pramono AA, Sukadi A, Chairulfatah A, Maskoen AM, et al.
Background As pediatric tuberculosis (TB) globally is still reported challenging in diagnosis, to date, a lot of efforts have been established to eliminate the disease including proper treatment regimen using anti-TB drugs. However, antituberculosis drug-induced hepatotoxicity (A…
Kalra A, Parija D, Raizada N, Sachdeva KS, Rao R, et al.
Background Diagnosis of TB in pediatric population poses several challenges. A novel initiative was implemented in several major cities of India aimed at providing upfront access to free-of-cost Xpert MTB/RIF to presumptive pediatric TB cases. This paper aims to describe the expe…
Vukugah TA, Ntoh VN, Akoku DA, Leonie S, Jacob A
…o meet the specific needs of children is critical to ending pediatric TB epidemic. Systematic reviews are increasingly informing policies in pediatric tuberculosis (TB) care and control. However, there is a paucity of information on pediatric TB research priorities. Methodology .…
Raj Narayan Yadav, Manpreet Bhalla, Yellanki Yashwanth Chowdary, Ajoy Kumar Verma, Gaurav Kaushik, et al.
**BACKGROUND:** Pediatric tuberculosis is an important subset of tuberculosis infection burden with a high detection gap due to paucibacillary nature. GeneXpert MTB/RIF assay detects rifampicin resistant (RR) Mycobacterium tuberculosis (MTB) that provides bacillary load and mutat…
Renee Gresh, Kimberly Davidow, Jeff Myers, D Morley
…s been a metric tracked for the US News and World Report in pediatric oncology. Electronic health record (EHR) based tools may be used to improve rates of vaccination. An oncology knowledgebase is an internal web portal that integrates relevant diagnostic and clinical data from t…
Nora Fritschi, Schmidt A.J., Jürg Hammer, Nicole Ritz, Swiss pediatric surveillance unit
…ckground:</i></b> In Europe, surveillance and monitoring of pediatric tuberculosis (TB) remains important, particularly in the light of migration in recent years. The aim of the study was to evaluate incidence rates of childhood TB and detailed diagnostic pathways and treatment. …
Money NM, Schroeder AR, Quinonez RA, Ho T, Marin JR, et al.
Importance Medical overuse is common in pediatrics and may lead to unnecessary care, resource use, and patient harm. Timely scrutiny of established and emerging practices can identify areas of overuse and empower clinicians to reconsider the balance of harms and benefits of the m…
Thomas VA, Crouse HL, Murray KO, Hsu DC, Camp EA, et al.
… The aim of this study was to perform a needs assessment of pediatric (PEM) and general emergency medicine (EM) provider knowledge, comfort, and current practice patterns in the evaluation of pediatric tropical infectious diseases. Methods An online survey was developed based on …
Mgode GF, Cox CL, Mwimanzi S, Mulder C
…ermined the performance of trained rats in the diagnosis of pediatric TB and whether they can improve detection rate compared to the standard of care. Methods Presumptive TB patients in 24 TB clinics in Tanzania were tested. Samples indicated as TB-positive by rats underwent conf…
Mae Anne Rizalyn Allam, Mary Jane Dolores Ayson
Objective: Pediatric HIV is a national health concern that has grown exponentially in the past 5 years. This study aimed to determine the clinico-demographic profile and outcome of pediatric HIV/AIDS patients 0-18 years old seen at the Western Visayas Medical Center (WVMC) HIV/AI…
Jeffrey I. Campbell, Thomas J. Sandora, Jessica E. Haberer
…ts to eliminate TB by 2030. Identification and treatment of pediatric LTBI requires completion of a complex care cascade. While attention has been given to LTBI care cascades in adults, to date there has been no attempt to map literature on the pediatric LTBI care cascade. Facili…
Lauren R Brown, Mariette Smith, Cari van Schalkwyk, Leigh F Johnson, Vanessa Mudaly, et al.
**BACKGROUND:** Pediatric tuberculosis (TB) remains a major public health concern in high-burden settings like the Western Cape (WC), South Africa. We analyzed geographic differences in TB burden among children and young adolescents, described temporal trends, and quantified gaps…
Nicolas A. Menzies, Tyler S. Brown, Jeffrey W. Eaton, Peter J. Dodd, Ted Cohen, et al.
…d dying from tuberculosis (TB). We estimated the additional pediatric TB cases and deaths that could occur over 2025-2034 if programmes supported by United States bilateral health aid and the Global Fund to Fight AIDS, Tuberculosis, and Malaria (Global Fund) are discontinued. Met…
Adusumelli Y, Tabatneck M, Sherman S, Lamb G, Sabharwal V, et al.
… to engaging in TB infection care is critical to preventing pediatric TB disease. We explored families' and clinicians' perspectives on pediatric TB infection diagnosis and care. Methods We conducted individual interviews and small group discussions with primary care and subspeci…
Trim Lajqi, Natascha Köstlin‐Gille, Christian Gille
…in 2020. Particularly, in low- and middle-income countries, pediatric infectious diseases remain a significant public health concern. During early development, infants rely mainly on the activity of the innate immune responses in the defense against invading pathogens. Until rece…
Bineeta Kashyap, Neha Gupta, Pooja Dewan, Puneeta Hyanki, Narendra Singh
… cough, low fever and weight loss. Radiological features in pediatric pulmonary TB may also remain non-specific, most typical being hilar or paratracheal lymphadenopathy. So the diagnosis remains difficult. Microbiological confirmation remains challenging due to suboptimal pulmon…
Gómez-Valverde JJ, Sánchez-Jacob R, Ribó JL, Schaaf HS, García Delgado L, et al.
…ly those under the age of 5 years. The complex diagnosis of pediatric TB, compounded by limited access to more accurate diagnostic tests, underscores the need for improved tools to enhance diagnosis and care in resource-limited settings. Objective This study aims to present a tel…
Madzgharashvili T, Salindri AD, Magee MJ, Tukvadze N, Avaliani Z, et al.
Background Among pediatric patients with multidrug-resistant tuberculosis (MDR-TB), limited data exist regarding treatment outcomes in the context of the new and repurposed second-line TB drugs (SLDs). We aimed to describe the treatment outcomes among pediatric MDR-TB patients re…
Epperson K, Crane C, Ingulli E
Donor derived infections (DDIs) in pediatric kidney transplant recipients remain challenging to diagnose and can result in serious morbidity and mortality. This review summarizes the current guidelines and recommendations for prevention, diagnosis, and treatment of unexpected DDI…
Sabila Salsabila, Ni Made Mertaniasih, Retno Asih Setyoningrum
…common result on the Xpert MTB/RIF examination in suspected pediatric TB cases. Abstract Introduction: The difficulty of diagnosing tuberculosis (TB) is the most significant challenge in pediatric pulmonary TB cases. More accurate and faster diagnostic tools are essential for det…
Peck GM, Staat MA, Huang FS, Khalil N, Boyce C, et al.
…ad of tuberculosis and the progression to active disease in pediatric patients. As of 2017, the short course combination regimen of weekly isoniazid and rifapentine (3HP) administered by directly observed therapy (DOT) has replaced 9 months of isoniazid as the standard of treatme…
Enrique G. Villarreal, Ricardo J. Estrada-Mendizábal, Emilia Ramos-Barrera, Pablo D Treviño-Valdez, Oscar Tamez‐Rivera
…cal trends of the different clinical presentations of TB in pediatric population. Methods A retrospective, cross-sectional study, carried out at a pediatric referral hospital in Mexico between 2012-2021. Pediatric patients diagnosed with TB were included. Descriptive statistics w…
Muljadi R, Koesbandono, Octavius GS
Introduction Despite medical advancement, pediatric pulmonary tuberculosis (PTB) still has high morbidity and mortality, due to challenging detection in clinical practice. Ultrasound has been touted as the next best diagnostic tool but currently, this claim is unfounded. Therefor…
Ananya S Willsraj, Suba Joice, Y Dishan, Blessed Singh, Ajin Chandran
…ials and methods: A cross-sectional study was done among 90 pediatric HHC (5–15 years) of 48 microbiologically confirmed pulmonary TB patients notified in Neyyattinkara TB unit from March 2021 to July 2022. Data were entered and analyzed using SPSS trial version 26. All qualitati…
Bineeta Kashyap, Neha Gupta, Pooja Dewan, Puneeta Hyanki, NarendraPal Singh
… of disease in TBM. We aimed to assess serum TNF-α level in pediatric patients with TB in association with clinicoradiological and microbiological features, with special reference to TBM. Materials and methods Serum TNF-α level was estimated using enzyme-linked immunosorbent assa…