Showing 26–50 of 200 documents
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Olbrich L, Verghese VP, Franckling-Smith Z, Sabi I, Ntinginya NE, et al.
Background Childhood tuberculosis remains a major cause of morbidity and mortality in part due to missed diagnosis. Diagnostic methods with enhanced sensitivity using easy-to-obtain specimens are needed. We aimed to assess the diagnostic accuracy of the Cepheid Mycobacterium tube…
Oshima K, Nakajima C, Hirata K, Hayashi H, Kodama EN, et al.
Tuberculosis remains a major public health concern. Millions of tuberculosis cases and associated deaths have been reported worldwide. The Indo-Oceanic lineage Mycobacterium tuberculosis is common in Southeast Asia and causes extrapulmonary lesions. Only a few case studies on thi…
Abiodun Ronke Ojewuyi, Abiona Oluwadamilola Odeyemi, A.O. Odeyemi, Amadin Aitua Olotu
Abstract Background Tuberculosis (TB) is a cause of high morbidity and mortality across the world but more so in developing countries. A large proportion of patients with tuberculosis present with extra-pulmonary disease which is often misdiagnosed or under-diagnosed. In Southwes…
Anak Agung Fendy Triwicaksana, Musofa Rusli, Muhammad Vitanata Arfijanto, Bramantono, Nasronudin Nasronudin, et al.
…ing to some infections such as pulmonary and extrapulmonary tuberculosis. A rare case of decreased CD4+ T cells is idiopathic CD4+ T cell lymphocytopenia, a rare and unexplained immunodeficiency syndrome with no evidence of HIV infection. In this case report, we are reporting a p…
Wanli Kang, Jiajia Yu, Cheng Liang, Quanhong Wang, L. Li, et al.
…le>Abstract</title> <bold>Background: </bold>Extrapulmonary tuberculosis (EPTB) is a significant health problem which can lead to severe morbidity and mortality. In clinical practice, EPTB can have a variety of nonspecific clinical manifestations and can be concurrent with other …
Amare W Tadesse, Noriah Maraba, Jason Alacapa, Katya Gamazina, Tanyaradzwa Dube, et al.
**BACKGROUND:** Tuberculosis remains a leading cause of death globally, particularly in countries with high tuberculosis and HIV burdens. Disruptions caused by the COVID-19 pandemic may have further impacted tuberculosis outcomes. This study examines on-treatment mortality and as…
Jiajia Yu, Yunqing Chang, Chen Liang, Shengsheng Liu, Liang Li, et al.
Extrapulmonary tuberculosis (EPTB) is a significant health problem which can lead to severe morbidity and mortality. In clinical practice, EPTB can have a variety of nonspecific clinical manifestations and can be concurrent with other types of EPTB. As information pertaining to c…
Neelam Chauhan, Anshu Sharma
Tuberculosis (TB) and HIV have been closely linked since the emergence of AIDS. Worldwide, TB is the most common opportunistic infection affecting HIV-seropositive individuals and it remains the most common cause of death in patients with AIDS. Aim is to determine the percentage …
Ekaterina Kulchavenya, Mahmadzarif Merganov
Introduction: The role of extrapulmonary tuberculosis (EPTB) in general and urogenital tuberculosis (UGTB) in particular is under-estimated in official statistics, medical practice and by the population. The purpose of this report was to estimate the relative importance of UGTB i…
P. K. Yаblonskiy, B. I. Vishnevskiy, N. S. Solovyova, Vladimir Galkin
…ive: to assess changes in the data on drug resistance of M. tuberculosis for 2015-2021 and compare it with data for 2012-2014. Subjects and Methods. Using continuous sampling, the frequency of drug resistance of Mycobacterium tuberculosis (MTB DR) was studied in isolates from 151…
Vandana Balgi, J Sanjana, D K Suneetha, Amrudha Surendran, Gowri Chandrashekar
Background: Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis, which has posed a constant challenge to mankind in its treatment due to increasing resistance and longer duration of treatment. The newer approach is to look towards strengthening host immune …
Aishwarya Alavandar
Background: Standard weight-based dosing of first-line anti-tuberculosis drugs does not consistently achieve therapeutic plasma concentrations in all patients. Inadequate drug exposure may contribute to poor treatment response, particularly in extrapulmonary and disseminated tube…
Надежда Игоревна Поркулевич, А. В. Мордык
…trend towards a decrease in the incidence of extrapulmonary tuberculosis is noted both in the Omsk region and throughout the Russian Federation Purpose of the study. To study anamnestic, epidemiological and clinical features of children diagnosed with renal tuberculosis and other…
Abhishek S, Saikia UN, Gupta A, Bansal R, Gupta V, et al.
Background: Intraocular tuberculosis (IOTB), an extrapulmonary manifestation of tuberculosis of the eye, has unique and varied clinical presentations with poorly understood pathogenesis. As it is a significant cause of inflammation and visual morbidity, particularly in TB endemic…
Rupali Rupali, Karan Sharma, N. C. Kajal
…lass="abstract"><strong>Background:</strong> Tuberculosis (TB) is primarily a disease of lungs but can affect any part of the body. Among extrapulmonary TB, tuberculosis of otorhinolaryngeal region is uncommon but not rare. Despite the best efforts of the RNTCP, tu…
Ayik R. Puspaningtyas, Ari S. Nugraha, Yuni Retnaningtyas, Siti Zulaiha
Tuberculosis (TB) is a chronic infectious disease caused by Mycobacterium tuberculosis (Mtb). Mtb affects not only the respiratory system but also other body organs, such as the lungs, leading to pulmonary and extrapulmonary TB, the brain, and the spine. Aspilia pluriceta from Me…
Y Hafeeza, M Rishitha, Naga Yeseswini S, Venu Babu A, Sumavi Sekhar J, et al.
Background: Tuberculosis is a global disease leading to cause death worldwide. The Revised National Tuberculosis Control Programme (RNTCP), Directly Observed Treatment Short Course (DOTS), was launched to reduce tuberculosis mortality, improve patient adherence to treatment, and …
van Leeuwen LM, Versteegen P, Zaharie SD, van Elsland SL, Jordaan A, et al.
…itis (TBM), the most severe extrapulmonary manifestation of tuberculosis, is caused by the pathogen Mycobacterium tuberculosis The M. tuberculosis complex includes seven lineages, all described to harbor a unique geographical dissemination pattern and clinical presentation. In th…
Alavandar A
Background Standard weight-based dosing of first-line anti-tuberculosis drugs does not consistently achieve therapeutic plasma concentrations in all patients. Inadequate drug exposure may contribute to poor treatment response, particularly in extrapulmonary and disseminated tuber…
Safira Amelia, Nastiti Kaswandani
Background: Tuberculosis remains a significant cause of mortality in children. Nutritional status is one of the major risk factors for tuberculosis severity. This study investigated the factors influencing nutritional status in tuberculosis patients. Methods: This is a retrospect…
Aishwarya Alavandar
…CKGROUND:** Standard weight-based dosing of first-line anti-tuberculosis drugs does not consistently achieve therapeutic plasma concentrations in all patients. Inadequate drug exposure may contribute to poor treatment response, particularly in extrapulmonary and disseminated tube…
Saha S
…ehend the diagnostic challenges of primary gastrointestinal tuberculosis (an uncommon extrapulmonary tuberculosis condition) utilizing the recently published case report of a young male with prolonged gastrointestinal symptoms and weight loss who received intermittent anti-tuberc…
Alehegn E, Gebreyohanns A, Berhane B, Wright J, Fantahun M, et al.
Background Extra pulmonary tuberculosis (EPTB) accounts for a significant proportion of tuberculosis (TB), a devastating disease of public health concern. The complexity of the cases, the involvement of many organs, resource constraints, and concerns regarding drug resistance mak…
Tebeje WT, Ayen AA, Argaw DA, Mulu TS, Abdulahi AA, et al.
Introduction and importance Tuberculosis (TB), a common chronic infectious disease, affected approximately 10.6 million people worldwide in 2021. While TB can affect the lungs (pulmonary TB) or other parts of the body, extrapulmonary TB, genital TB is a rare form of extrapulmonar…
А. Г. Наумов, Konstantin Boronin, K V Bokova, N S Zherebyat'eva, E. V. Zhukova, et al.
Timely detection of tuberculosis among the population, both pulmonary and, especially, extrapulmonary, is a priority task of domestic and foreign health care. Often, extrapulmonary forms of tuberculosis mask various other pathologies. For example, laryngeal tuberculosis may be ma…