Showing 26–50 of 200 documents
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Divya Dayal
Background of the Study: Tuberculosis is a global public health issue despite the discovery of the causal bacterium over 100 years ago and availability of effective medications and vaccines for prevention and cure. Tuberculosis has a global incidence rate of 119 per lakh, with lo…
Musisi E, Sessolo A, Kaswabuli S, Zawedde J, Byanyima P, et al.
…ted the utility of a novel RNA-based quantitative test, the tuberculosis molecular bacterial load assay (TB-MBLA), for the detection and quantification of Mycobacterium tuberculosis in stool. Stools from 100 adult individuals were treated with OMNIgene-sputum reagent and tested u…
Adane Bitew, Solomon Bati
…y mycosis is increasing and often misdiagnosed as pulmonary tuberculosis in developing countries where the prevalence of pulmonary tuberculosis is high. Objective: To determine the prevalence of pulmonary mycosis and pulmonary tuberculosis fungal co-infections. Methods: A hospita…
Umar F, Hatta M, Husain DR, Natzir R, Dwiyanti R, et al.
…ssion level of the Rv1250 efflux pump gene in Mycobacterium tuberculosis isolated from individuals with tuberculosis who received drug therapy, at the 1st, 3rd and 5th months, and newly diagnosed patients with tuberculosis who will receive drug therapy (0 month). The study was a …
М. А. Плеханова, В. А. Аксенова, Л. А. Кривцова
…ctive: to determine predictors of the development of latent tuberculosis infection (LTBI) and tuberculosis in children and adolescents. Subjects and methods . A study was carried out, including testing induced IFN-y and assessment of genotypes of the polymorphic variant of IFNG g…
Agus Khoirul Anam
Abstract: Tuberculosis is an infectious disease caused by germs of a group of mycobacterium namely mycobacterium tuberculosis. The objective of the research is to identify Tuberculosis patients complaints in side effects of drug treatment anti-tuberculosis and factors that influe…
Anand Kumar, Aparjot Singh, Sudhir Chaudhri, Sanjay Kumar Verma, Kiran Pandey, et al.
Background: Mycobacterium tuberculosis, most commonly, infects the lungs (pulmonary TB). Most cases of female genital TB (FGTB) are found in premenopausal women, theoretically because an atrophic endometrium provides a poor milieu for mycobacterial growth. Female genital TB gener…
Krunal Patel, Kinjal Patel, Pooja Gandhi, Bhavini Rathwa, Dipak M. Nakum
Introduction: Tuberculosis is a chronic infectious disease caused by predominantly Mycobacterium tubercle bacilli. Pediatric tuberculosis is among the top 10 causes of death in children. India accounts for one fourth of the global tuberculosis burden, standing one among the thirt…
Avula A, Ngu S, Mansour W, Gurala D, Maroun R
…ted with poor prognosis seen in advanced disease, laryngeal tuberculosis (LTB) now represents only 1% of all cases of tuberculosis (TB). The incidence of LTB has decreased drastically with the introduction of anti-tubercular drugs. LTB can be primary or secondary to pulmonary tub…
Berhan A, Almaw A, Solomon Y, Legese B, Damtie S, et al.
Background Tuberculosis is a communicable disease, mainly caused by the bacillus Mycobacterium tuberculosis. Globally, TB is the ninth leading cause of death, with developing countries bearing most of the burden. The discovery of chemotherapy lead to significant improvements in p…
Berhan A, Almaw A, Solomon Y, Legese B, Damtie S, et al.
Background Tuberculosis is a communicable disease, mainly caused by the bacillus Mycobacterium tuberculosis. Globally, TB is the ninth leading cause of death, with developing countries bearing most of the burden. The discovery of chemotherapy lead to significant improvements in p…
Wubu B, Jemal M, Million Y, Gizachew M
…r areas are important sites for disseminating Mycobacterium tuberculosis among individuals living in such areas. This study examined patients with suspected pulmonary tuberculosis (PTB) visiting the Abrihajira and Metema hospitals in northwest Ethiopia to investigate the prevalen…
Anagoni Srikar, B. V. Ramana, Parnakshi Sarma, Alladi Mohan, Abhijit Chaudhury
Abstract Background: Multidrug-resistant tuberculosis (MDR-TB) is a global public health problem. Methods: We tested 104 strains each of Mycobacterium tuberculosis complex ( Mtb ) isolated from new cases and previously treated cases against four first line anti-tuberculosis agent…
Zhang L, Ma H, Wan S, Zhang Y, Gao M, et al.
Background Differential diagnosis of active tuberculosis (ATB) and latent tuberculosis infection (LTBI) has been a challenge for clinicians in high TB burden countries. The purpose of this study was to improve the accuracy of differential diagnosis of ATB and LTBI by using fluore…
Nkechi Eucharia Egbe, Azizat Olatunji, Peter A. Vantsawa
The accurate diagnosis of tuberculosis (TB), detection of drug‐resistant TB and knowledge of the associated risk factors can reduce transmission of TB in the community. Therefore this study was carried out to determine the prevalence of Mycobaterium tuberculosis ( MTB ) and its r…
M. S. Ramya, Jyothi Jadhav, T S Ranganath
Background: Tuberculosis (TB) is a top infectious disease killer worldwide. In India although Revised National Tuberculosis Control Programme (RNTCP) has seen significant success in TB treatment, patient non-adherence or lost to follow up continue to persist and are influenced by…
Holmberg P, Janoušková M, Schmidt T, Neumann A, Olsson O, et al.
Background Interferon-γ release assays (IGRAs) for tuberculosis infection (TBI) cannot distinguish different stages of the TBI spectrum (including spontaneously cleared infection). We investigated patterns of Mtb-specific blood mediators in people with and without TBI during tube…
Pan SW, Su WJ, Chan YJ, Chuang FY, Feng JY, et al.
Objectives The timely diagnosis of pulmonary tuberculosis (PTB) is challenging. Although pathogen-derived circulating cell-free DNA (cfDNA) has been detected in humans, the significance of Mycobacterium tuberculosis (MTB)-cfDNA detection in patients with PTB remains unclear. Meth…
Luo Y, Xue Y, Yuan X, Lin Q, Tang G, et al.
… is no rapid and effective method for distinguishing active tuberculosis (ATB) from latent tuberculosis infection (LTBI), the discrimination between these two statuses remains challenging. This study sought to investigate the value of nutritional indexes and tuberculosis-specific…
Dipali Maganbhai Gavali, Binita Aring, Hiral Gadhavi, Akhlakahemad Nathamehta, Abhishek B Dave, et al.
… high prevalence in India, accounting for one-fourth of the Tuberculosis (TB) cases in the world. In our study, we aimed to find the prevalence of Pre XDR-TB and XDR-TB amongst newly diagnosed cases of pulmonary MDR-TB who had never been previously treated with second-line drugs.…
Luo Y, Xue Y, Mao L, Lin Q, Tang G, et al.
…ackground Rapid and effective discrimination between active tuberculosis (ATB) and latent tuberculosis infection (LTBI) remains a challenge. There is an urgent need for developing practical and affordable approaches targeting this issue. Methods Participants with ATB and LTBI wer…
Lifan Zhang, Huimin Ma, Qiping Ge, Yueqiu Zhang, Xiaochun Shi, et al.
Abstract Background To establish the Mycobacterium tuberculosis (MTB) specific IFN-γ/IL-2/TNF-α-FluoroSpot assay, and preliminarily evaluate its accuracy of differential diagnosis of active tuberculosis (ATB) and latent tuberculosis infection (LTBI). Methods Patients with patholo…
Dekel Shlomi, Inbal Galor, Anna More, Bernice Oberman, Lizi Fireman
<b>Background:</b> Treatment for latent tuberculosis (TB) is traditionally based on the result of the tuberculin skin test (TST) which is often falsely positive. The Interferon gamma release assays (IGRA) are more specific but considerably more expensive. Several studies have imp…
D. S. Esmedlyaevа, Н. П. Алексеева, Marina Dyakova
…of adverse treatment outcomes in individuals with pulmonary tuberculosis (PT) is relevant due to the worldwide increase in drug resistance of Mycobacterium tuberculosis (MBT) strains to anti-tuberculosis drugs (PTP). Matrix metalloproteinases (MMPs) and their tissue inhibitors (T…
Shaohua Yao, Yan Jy, Li L, Daqing Ma, Jun Liu, et al.
…Wang,1 Aimin Wang,1 Fangjin Bao,1 Zekun Zhang,1 Xundi Bao1 1Tuberculosis Prevention and Treatment Institute of Anhui Province (Anhui Chest Hospital), Hefei 230022, Anhui, People’s Republic of China; 2Affiliated Psychological Hospital of Anhui Medical University, Hefei Fourt…