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Cuadros EN, Calzada-Hernández J, Clemente D, Martín SG, Silveira LF, et al.
…rovides practical recommendations on infection screening in pediatric patients with immune-mediated rheumatic diseases and immunosuppressive therapies. For this reason, a qualitative approach was applied. A narrative literature review was performed via Medline. Primary searches w…
Lee WS, Arai K, Alex G, Treepongkaruna S, Kim KM, et al.
Disease phenotype of pediatric inflammatory bowel disease (PIBD) in children from the Asia-Pacific region differs from that of children from the West. Many parts of Asia are endemic for tuberculosis, making diagnosis and management of pediatric Crohn's disease a challenge. Curren…
Kanjanaphan T
…igation of LTBI in healthcare personnel (HCPS) working with pediatric patients with active pulmonary TB and report the side effects of 12-week-isoniazid and rifapentine (3HP). Methods This contact investigation reviewed HCPS who were in close contact with pediatric pulmonary TB. …
Brendan Mullen, Joy Githua, Jaclyn N Escudero, Jerphason Mecha, Lucy Kijaro, et al.
…lescents worldwide. Diagnostic challenges are pronounced in pediatrics, in which collecting respiratory specimens is challenging and TB is often paucibacillary, leading to delayed diagnosis and increased mortality. We describe the protocol and methodology of the Pediatric TB Diag…
Lee WS, Arai K, Alex G, Treepongkaruna S, Kim KM, et al.
Pediatric inflammatory bowel disease (PIBD) is rising rapidly in many industrialised and affluent areas in the Asia Pacific region. Current available guidelines, mainly from Europe and North America, may not be completely applicable to clinicians caring for children with PIBD in …
Olbrich L, Nliwasa M, Sabi I, Ntinginya NE, Khosa C, et al.
…perfect reference standard, Rapid and Accurate Diagnosis of Pediatric Tuberculosis Disease (RaPaed-TB) was designed following a rigorous and complex methodology. This allows for the determination of diagnostic accuracy of novel assays and combination of testing strategies for opt…
Martinelli M, Giugliano FP, Strisciuglio C, Urbonas V, Serban DE, et al.
…accine-preventable diseases and opportunistic infections in pediatric inflammatory bowel disease (IBD) are increasingly recognized issues. The aims of this study were to evaluate vaccinations, immunization status, and consequent therapeutic management in children with IBD and to …
Neyro SE, Squassi IR, Medín M, Caratozzolo A, Martínez Burkett A, et al.
Extrapulmonary tuberculosis accounts for 15-20 % of all clinical presentations of tuberculosis. Peripheral tuberculous lymphadenitis is the second most common presentation of extrapulmonary tuberculosis in children, after pleural tuberculosis, in Argentina. We analyzed 92 patient…
Clemente Garulo D, Núñez-Cuadros E, Camacho Lovillo M, Calzada-Hernández J, Guillén Martín S, et al.
…e practical recommendations on prophylaxis for infection in pediatric patients with immune-mediated rheumatic diseases receiving/scheduled to receive immunosuppressive therapy. A qualitative approach was applied. A narrative literature review was performed via Medline. Primary se…
Clemente D, Cuadros EN, Lovillo MC, Hernández JC, Martín SG, et al.
…s to provide practical recommendations on the management of pediatric patients with immune-mediated rheumatic diseases receiving immunosuppressive therapies. The recommendations specifically address the cases of surgery, fever, and opportunistic infections (varicella, herpes-zost…
Beyer RS, Franklin AJ, Hatter MJ, Nguyen A, Brown NJ, et al.
…re characterized by inflammation of the endplate-disc unit. Pediatric spinal infection is rare and challenging to diagnose due to vague presenting symptoms. Most cases are conservatively managed with surgery rarely indicated. The authors performed a systematic review to study the…
Vukugah TA, Akoku DA, Tchoupa MM, Lambert E
…ttitude, and practice (KAP) of healthcare workers (HCWs) on pediatric TB management and its associated factors in the Centre Region of Cameroon. Methods A cross-sectional study was conducted between January and March 2022. HCWs, selected through a multistage sampling technique in…
Sangeeta Kumari, Aarti Agarwal, Manveer Singh, Komal Grover, Jagdish Chandra, et al.
…atment (TPT) in India remains suboptimal, especially in the pediatric age group. This study aimed to determine the missed opportunities of disease identification and prevention among pediatric TB cases with a documented history of household exposure to a TB index case. Prima…
James Marcomic Maragia, Jepchirchir Kiplagat, Onyango Dickens, Lazarus Odeny, Stephen Olubulyera, et al.
…nya, approximately 77,000 TB cases were reported, with pediatric TB contributing to 9.6% of all cases and 4.8% of TB-related deaths. Turkana County, a pastoralist region, accounted for 19% of the national pediatric TB burden. The specific drivers of this high pediatric TB ra…
Van Brusselen D, Simons E, Luendo T, Habarugira D, Ngowa J, et al.
… covering a population of 520,000, with an elevated rate of pediatric malnutrition. In July 2017, an adapted MSF pediatric TB diagnostic algorithm, including Xpert MTB/RIF on gastric aspirates (GAs), was implemented. The aim of this study was to evaluate whether the introduction …
Earley M, Chirenda J, Highet A, Mujuru HA, Yang Z
Pediatric tuberculosis (TB) represents a major barrier to reducing global TB mortality, especially in countries confronting dual TB and human immunodeficiency virus (HIV) epidemics. Our study aimed to characterize pediatric TB epidemiology in the high-burden setting of Harare, Zi…
Mandera I, Ayebazibwe G, Tumusiime A, Byamukama T, Mfitumukiza V, et al.
…rculosis (TB) and >214,000 died in 2022. The integration of pediatric TB screening should help in the identification and management of cases among children attending clinics at entry points. This study aimed to establish the extent of integrating pediatric TB screening into mains…
Siddalingaiah N, Chawla K, Nagaraja SB, Hazra D
Pediatric tuberculosis is a major cause of mortality and morbidity in children due to high transmission, poor diagnostic tools, and various respiratory diseases mimicking TB. Identifying risk factors will provide evidence for clinicians to strongly relate their diagnosis to the a…
Kim Y, Bae KS, Choi UY, Han SB, Kim JH
Background The treatment of pediatric patients with latent tuberculosis infection (LTBI) is a crucial TB control strategy. LTBI is not a reportable communicable disease, and data regarding LTBI treatment in pediatric patients in Korea are scarce. This study aimed to investigate t…
Harrist AV, McDaniel CJ, Wortham JM, Althomsons SP
Introduction Pediatric tuberculosis (TB) cases are sentinel events for Mycobacterium tuberculosis transmission in communities because children, by definition, must have been infected relatively recently. However, these events are not consistently identified by genotype-dependent …
Marina Bahaa Monir Zakhary Gad El Sayed, Dennis Tai, Lucy Yu, Daniel Novak, Amrita Dosanjh
…tcomes of pulmonary NTM infections in a non-cystic fibrosis pediatric population from four distinct age groups. **METHODS:** A retrospective study as cross-sectional design for data collection from the TriNetX platform, a global electronic health record database. Inclusion crite…
Alicia Hernanz-Lobo, Juan J Gómez-Valverde, Ángel Lancharro, Ramón Sánchez-Jacob, José Luis Ribó, et al.
…t radiography (CXR) is the most widely used imaging tool in pediatric tuberculosis (TB) diagnostic pathways, and remains central in current WHO algorithms. However, its standalone diagnostic accuracy has not been well established in standardized multicenter evaluations. This stud…
Wang DM, Wang C, An Q, Yang Q, Liao Y
…ample, dynamic epidemiology, and characteristic analysis of pediatric tuberculosis (TB) in Southwest China is not clear. Herein, we conducted descriptive dynamic epidemiology, characteristic analysis and geographical distribution study of pediatric TB inpatients in Southwest Chin…
Weldetsadik AY, Abayneh M, Abraha M, Sirgu S, Bekele D
Introduction Most previous pediatric COVID-19 studies reported milder disease in children. However, there are limited pediatric data from low-income settings. We aimed to assess the characteristics and outcomes of pediatric COVID-19 in Ethiopia. Setting St. Paul's COVID-19 treatm…
Xiaojun Wang, Cuili Yang, Meilan Zhou, Cuiping Xiao, Xiaolu Yu, et al.
**BACKGROUND:** Research on the economic burden of pediatric tuberculosis (TB) remains scarce. This study aims to investigate the hospitalization characteristics, direct medical expenses, and key determinants of hospitalization costs in pediatric TB patients. **METHODS:** We con…