Showing 1–25 of 200 documents
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Nichols BE, de Nooy A, Cassim N, Hans L, da Silva MP, et al.
…tment is necessary. We, therefore, sought to understand the health and economic impacts of the molecular diagnostic programme in South Africa, to deepen the understanding of the broad value of diagnostics and guide future healthcare investments. Methods We calculated the 10-year …
Shah S, Abbas G, Hanif M, Anees-Ur-Rehman, Zaman M, et al.
Background : Health-care systems in Asian countries are diverse. The economic evaluation provides information on how to make efficient use of the resources available to obtain the maximum benefits. In Asia, diseases such as cardiovascular diseases (CVDs), diabetes mellitus (DM), …
Steffany Vucetich, Kelly DeToy, Shilah F Waters, Nicole La Ruta, Yeonsoo Baik, et al.
… arrhythmias, and sudden death. This condition not only has health impacts in the form of morbidity and premature mortality but also carries significant economic burden related to its cost of care. This study aims to evaluate the current health and economic burden of Chagas cardi…
Chaofan Wang, Xiaozhen Lai, Kaja Abbas, Koen B Pouwels, Haijun Zhang, et al.
…(EPI), initiated by WHO in 1974, is a cornerstone of public health. China's EPI covers more than a sixth of the world's population and includes eight routine vaccines with high coverage rates. This study aimed to estimate health and economic impacts of China's EPI over the past 5…
Menzies NA, Bellerose M, Testa C, Swartwood NA, Malyuta Y, et al.
…mate the potential impact of effective global TB control on health and economic outcomes in the United States. Methods: We estimated outcomes using linked mathematical models of TB epidemiology in the United States and migrants' birth countries. A base-case scenario extrapolated …
Swartwood NA, Li Y, Regan M, Marks SM, Barham T, et al.
…nd case-fatality rates in the US. Objective To estimate the health outcomes and economic cost of TB disparities among US-born persons from 2023 to 2035. Design, setting, and participants Generalized additive regression models projecting trends in TB incidence and case-fatality ra…
Foster N, Tadesse AW, McQuaid CF, Gosce L, Abdurhman T, et al.
…ementing DATs in Ethiopia. Methods and design A total of 78 health facilities have been randomised (1:1:1) into one of two intervention arms or a standard-of-care arm. Approximately 50 participants from each health facility will be enrolled on the trial. Participants in facilitie…
Machlaurin A, Pol SV, Setiawan D, van der Werf TS, Postma MJ
…ions, target populations, and vaccine types. The Quality of Health Economic Studies (QHES) instrument was used to assess the quality of the studies included in the analysis. Expert opinion : Most of the studies showed a favorable economic profile of BCG vaccination. Selective str…
Baggaley RF, Vegvari C, Dimala CA, Lipman M, Miller RF, et al.
…ences. Databases were searched 1980-2020. Studies including health economic evaluation of LTBI screening of PLWH in lower TB incidence countries ( Results: Of 2,644 articles screened, nine studies were included. Cost-effectiveness estimates of LTBI screening/PT for PLWH varied wi…
Van Ginderdeuren E, Bassett J, Hanrahan CF, Mutunga L, Van Rie A
…wait time and task-shifted to delegate tasks to lower cadre healthcare workers, and result was compared to TST reading by high cadre research staff. TST reading and placement cost to the health system and patients were estimated. Simulations of health system costs were performed …
Ryckman TS, McQuaid CF, Cohen T, Menzies NA, Kendall EA
…ective of tuberculosis regimen development. We modelled the health and economic benefits of such a regimen and analysed which of its features contribute most to impact and savings. Methods We constructed a mathematical model of tuberculosis treatment parameterised with data from …
Menzies NA, Shrestha S, Parriott A, Marks SM, Hill AN, et al.
…o progress to tuberculosis (TB). We estimated the potential health and economic benefits of diagnostics with improved discrimination for LTBI that will progress to TB. Methods A base case scenario represented current LTBI testing and treatment services in the United States in 202…
Sumner T, Clark RA, Mukandavire C, Portnoy A, Weerasuriya CK, et al.
Background Tuberculosis remains a major public health problem in South Africa, with an estimated 300,000 cases and 55,000 deaths in 2021. New tuberculosis vaccines could play an important role in reducing this burden. Phase IIb trials have suggested efficacy of the M72/AS01 E vac…
Sonawane C, Yirga G, Carter NH
…anthropogenic waste for food can remove pathogens that pose health risks to humans and livestock, thereby saving lives and money. Quantifying these benefits is rare, yet can lead to innovative conservation solutions. To assess these benefits, we examined the feeding ecology and p…
Mao JJ, Zang X, Yue WL, Zhai PY, Zhang Q, et al.
…in a phase III trial. We aim to assess the population-level health and economic impacts of introducing Vaccae vaccination to inform policy-makers. Methods We evaluated a potential national Vaccae vaccination programme in China initiated in 2024, assuming 20 years of protection, 9…
Clark RA, Weerasuriya CK, Portnoy A, Mukandavire C, Quaife M, et al.
…ulation-level impact are needed. We estimated the potential health and economic impact of M72/AS01 E and BCG-revaccination in India and investigated the impact of variation in vaccine characteristics and delivery strategies. Methods We developed an age-stratified compartmental tu…
Pareek M, Eborall HC, Wobi F, Ellis KS, Kontopantelis E, et al.
…alitative sub-study to understand the views of migrants and healthcare professionals to the new testing policy in primary care. Finally, we will evaluate the cost-effectiveness of combined infection testing for migrants in primary care. Ethics and dissemination The study has rece…
de Necker M, de Beer JC, Stander MP, Connell CD, Mwai D
…ients on ARVs. Like many resource limited settings, Kenya's healthcare system faces serious challenges in effectively providing quality health services to its population. Increased investments to strengthen the country's capacity to diagnose, monitor and treat diseases, particula…
Yue WL, Zhai PY, Mao JJ, Ma JF, Ren WL, et al.
Abstract Introduction Tuberculosis (TB) is a major global health issue, particularly, in India and South Africa. We aim to evaluate the potential of the new TB vaccine, Vaccae, to enhance TB control by integrating with active case finding (ACF) strategies in these regions. Method…
Hailu G, Etefa M, Begna F
…bacterium tuberculosis complex, highly impacting the public health and economy of the country in endemic areas. Retrospective and cross-sectional study was conducted between March and August 2021. For knowledge, attitude, and practices study, five villages were randomly selected …
Clark RA, Portnoy A, Weerasuriya CK, Sumner T, Bakker R, et al.
Background India has the largest tuberculosis burden, but the all-age prevalence in 2021 ranged from 747/100,000 in Delhi to 137/100,000 in Gujarat. No modelling studies have compared the potential impact of new tuberculosis vaccines in regions with differing disease and infectio…
Pei-Yao Zhai, Xiao Zang, Ting Jiang, Jian Feng, Bin Zhang, et al.
**BACKGROUND:** China faces high burden of multidrug-resistant or rifampicin-resistant tuberculosis (MDR/RR-TB). We aimed to evaluate the impacts of Vaccae vaccination and enhanced drug-resistant TB (DR-TB) management strategies. **METHODS:** Using a compartmental model calibrat…
Claborn DM
… of a country's economy can have significant impacts on the health and healthcare infrastructure of the country. This paper compares the collapse of three national economies from widely separated regions: Venezuela, Zimbabwe, and the countries of the former Soviet Union. Despite …
Jiang T, Chen XS
…istance (AMR) has become a global threat to not only public health impacts but also clinical and economic outcomes. During the past decades, there have been many studies focusing on surveillance, mechanisms, and diagnostics of AMR in infectious diseases but the impacts on public …
Goryoka GW, Lokossou VK, Varela K, Oussayef N, Kofi B, et al.
…se a significant threat to human, animal, and environmental health. The Economic Community of West African States (ECOWAS) has endured a significant burden of zoonotic disease impacts. To address zoonotic disease threats in ECOWAS, a One Health Zoonotic Disease Prioritization (OH…