Showing 126–150 of 200 documents
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Mishra H, Reeve BWP, Palmer Z, Caldwell J, Dolby T, et al.
Background Xpert MTB/RIF Ultra (Ultra) is a new test for tuberculosis undergoing global roll-out. We assessed the performance of Ultra compared with Xpert MTB/RIF (Xpert) in an HIV-endemic setting where previous tuberculosis is frequent and current test performance is suboptimal.…
Jin J, Geng H, Li Y, Wang M, Yang S, et al.
…ness and its influencing factors of patients with pulmonary tuberculosis on preferential policies for tuberculosis prevention and treatment in Shandong, China. A total of 858 patients with pulmonary tuberculosis between January 1, 2018 and September 30, 2019 were surveyed with qu…
Risco D, Martínez R, Bravo M, Fernández Llario P, Cerrato R, et al.
…ground Wild boar is an important reservoir of Mycobacterium tuberculosis variant bovis , the main causative agent of bovine tuberculosis (bTB). A proportion of tuberculosis (TB)-affected wild boars shed M tuberculosis by nasal route, favouring the maintenance of bTB in a multihos…
Winter JR, Smith CJ, Davidson JA, Lalor MK, Delpech V, et al.
… known to increase the likelihood of reactivation of latent tuberculosis to active TB disease; however, its impact on tuberculosis infectiousness and consequent transmission is unclear, particularly in low-incidence settings. Methods National surveillance data from England, Wales…
AlHamawi R, Khader Y, Abaza H, Satyanarayana S, Wilson N, et al.
Background Tuberculosis knowledge, practices, and perceived stigma and discrimination among patients with tuberculosis are key factors for the management of the disease. Objectives The objectives of the study were to assess knowledge, practices, perceived stigma and discriminatio…
Ketema W, Woubishet K, Tesfaye S, Gutema S, Taye K, et al.
Background Tuberculosis is commonly detected late or not at all in HIV-positive people. Rapid and sensitive molecular tests like Gene X-pert have recently become available to replace or supplement existing conventional tests for detecting tuberculosis, and the World Health Organi…
Yu J, Liu M, Mijiti X, Liu H, Wang Q, et al.
…on between vitamin D receptor ( VDR ) gene polymorphism and tuberculosis susceptibility, as well as the potential interaction of host genetic factors with the heterogeneity of Mycobacterium tuberculosis in the population from Xinjiang, China. Methods From January 2019 to January …
Nindrea RD, Sari NP, Harahap WA, Haryono SJ, Kusnanto H, et al.
… data presents a survey data describing multidrug-resistant tuberculosis, tuberculosis patients characteristics and stress resilience during COVID-19 pandemic in West Sumatera Province, Indonesia. The data were gathered from multidrug-resistant tuberculosis, tuberculosis patients…
Sadovska D, Nodieva A, Pole I, Vīksna A, Ķimsis J, et al.
Background Current tuberculosis treatment regimens primarily rely on phenotypic drug susceptibility testing and rapid molecular assays. Although whole-genome sequencing (WGS) offers a promising alternative, disagreements between phenotypic and molecular testing methods remain. In…
Liu M, Wang Q, Liu H, Yin C, Mijiti X, et al.
…lymorphisms in MBL2 may contribute to the susceptibility to tuberculosis. The aim of the present study was to determine the associations of the polymorphisms of five loci (rs1800450, rs1800451, rs7096206, rs7095891, and rs11003125) in the MBL2 gene with susceptibility to tubercul…
Molla Y, Wubetu M, Dessie B
Background Tuberculosis caused by susceptible mycobacterium tuberculosis strains is effectively treated by the first-line anti-tuberculosis drugs. However, most antibacterial drugs are known to induce hepatotoxicity which may limit their adherence and hence lead to the developmen…
Mei YM, Zhang WY, Sun JY, Jiang HQ, Shi Y, et al.
Objectives Cutaneous tuberculosis with various manifestations can be divided into several clinical types according to the host's immune status and infective route. However, the etiological factors of this disease remain unclear. The objective of this study is to investigate the p…
Ishikawa CS, Matsuo OM, Sarno F
… To describe the characteristics of patients diagnosed with tuberculosis and latent tuberculosis infection. Methods A retrospective study, between 2012 and 2015, with data from patients of Programa Einstein na Comunidade de Paraisópolis. To evaluate possible factors associated wi…
Seifert M, Vargas E, Ruiz-Valdepeñas Montiel V, Wang J, Rodwell TC, et al.
Outside of the ongoing COVID-19 pandemic, tuberculosis is the leading cause of infectious disease mortality globally. Currently, there is no commercially available point-of-care diagnostic that is rapid, inexpensive, and highly sensitive for the diagnosis of active tuberculosis d…
Olbrich L, Verghese VP, Franckling-Smith Z, Sabi I, Ntinginya NE, et al.
Background Childhood tuberculosis remains a major cause of morbidity and mortality in part due to missed diagnosis. Diagnostic methods with enhanced sensitivity using easy-to-obtain specimens are needed. We aimed to assess the diagnostic accuracy of the Cepheid Mycobacterium tube…
Rajamanickam A, Ann Daniel E, Dasan B, Thiruvengadam K, Chandrasekaran P, et al.
Background The progression from Mycobacterium tuberculosis infection to active tuberculosis disease varies among individuals, and identifying biomarkers to predict progression is crucial for guiding interventions. In this study, we aimed to determine plasma immune biomarker profi…
Djika M, Koudokpon CH, Dougnon VT, Sanoussi N, Alphazazi S, et al.
Introduction tuberculosis remains a major public health problem, with continuing high levels of prevalence, and mortality. In Niger, the incidence of tuberculosis remains high. This study aims to investigate the epidemiology of pulmonary tuberculosis at the National Anti-Tubercul…
Li QH, Zhang Y, Zhao MM, Gu Y, Hu Y, et al.
…eous application and testing method to detect Mycobacterium tuberculosis rRNA (SAT-TB) with the endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) biopsy specimens to differentiate sputum-negative tuberculosis from sarcoidosis. In the first part, we vali…
Oshima K, Nakajima C, Hirata K, Hayashi H, Kodama EN, et al.
Tuberculosis remains a major public health concern. Millions of tuberculosis cases and associated deaths have been reported worldwide. The Indo-Oceanic lineage Mycobacterium tuberculosis is common in Southeast Asia and causes extrapulmonary lesions. Only a few case studies on thi…
Sari NIP, Mertaniasih NM, Soedarsono, Maruyama F
…nd accurate diagnosis are very important in managing active tuberculosis because they provide an advantage in preventing further disease transmission. In accordance with the recommendation of the World Health Organization, the Indonesian Tuberculosis Control Program uses the acid…
Kahase D, Desta K, Yaregal Z, Yenew B, Driba G, et al.
…ing Ethiopia. Hence, we aimed to assess the magnitude of M. tuberculosis and nontuberculous mycobacteria (NTM) among presumptive pulmonary tuberculosis patients attending St. Paul's hospital Medical College, Addis Ababa, Ethiopia. Methods A cross-sectional study was conducted fro…
Poudyal IP, Khanal P, Mishra SR, Malla M, Poudel P, et al.
…e co-morbidity of cardiometabolic diseases in patients with Tuberculosis adds a significant burden in current health systems in developing countries including Nepal. The main objective of this study was to explore cardiometabolic risk factors among patients with Tuberculosis. Met…
Kanabalan RD, Lee LJ, Lee TY, Chong PP, Hassan L, et al.
Mycobacterium tuberculosis complex (MTBC) refers to a group of mycobacteria encompassing nine members of closely related species that causes tuberculosis in animals and humans. Among the nine members, Mycobacterium tuberculosis (M. tuberculosis) remains the main causative agent f…
Jansen-Aaldring N, van de Berg S, van de Berg S, van den Hof S
…nd practices of patient support during treatment for active tuberculosis and for latent tuberculosis infection in European countries with a low incidence of tuberculosis and to identify potential best practices. Background Policies, practices and its' evaluations from similar set…
Ehlers LP, Bianchi MV, Argenta FF, Lopes BC, Taunde PA, et al.
Tuberculosis is a common zooanthroponosis in humans with a high incidence in Brazil, but it may also affect non-human primates (NHPs), of which Old World primates are most commonly involved. Nonetheless, its occurrence in New World primates is unknown, and therefore, this study a…