Showing 51–75 of 200 documents
Sorted by hybrid relevance (keyword + semantic via RRF)
Thibaut Morel-Journel, Christophe Guyeux, Christophe Sola
Lineage 1 is an ancestral lineage of the Mycobacterium tuberculosis complex (MTBC) comprising five sublineages. In a previous study, we suggested that a representative of sublineage L1.1.3, present in both Mozambique and northern Brazil, SIT129, may have been brought to Brazil by…
Nalunjogi J, Mucching-Toscano S, Sibomana JP, Centis R, D'Ambrosio L, et al.
…s growing on the overall impact of the COVID-19 pandemic on tuberculosis (TB) services, global studies based on national data are needed to better quantify the extent of the impact and the countries' preparedness to tackle the two diseases. The aim of this study was to compare th…
Kay AW, DiNardo AR, Dlamini Q, Kahari J, Mndzebele T, et al.
… are increasingly used in children to establish evidence of tuberculosis (TB) infection and to assist in the diagnosis of TB disease. The QuantiFERON-TB Gold In-Tube assay is being phased out in favor of a next-generation test, the QuantiFERON-TB Gold Plus (QFT-Plus) assay. The Q…
Sharma N, Bakshi R, Basu S, Zode M, Arora R, et al.
…nitiation, implementation and treatment completion rates of tuberculosis (TB) preventive therapy (TPT) using 3HP (INH-Rifapentine) among household contacts of microbiologically confirmed drug sensitive TB cases on anti-tubercular treatment under programmatic real-world settings. …
Woodruff R, Pratt R, Kolasa M
Problem/condition Elimination of tuberculosis (TB) is defined as reducing TB disease incidence in the United States to less than 1 case per million persons per year. In 2022, TB incidence in the United States was 2.5 TB cases per 100,000 persons. CDC's TB program developed a set …
Alemu A, Diriba G, Seid G, Wondimu A, Moga S, et al.
Objectives To assess tuberculosis (TB) and associated factors among patients with presumptive TB with chronic kidney disease (CKD). Methods A prospective cross-sectional study was conducted from January to December 2023 among 381 patients with CKD attending six hospitals found in…
Nababan B, Triasih R, Chan G, Dwihardiani B, Hidayat A, et al.
In Indonesia, the implementation of tuberculosis (TB) contact investigation is limited, with low detection rates. We report the yield of and risk factors for TB disease and infection for household contacts (HHCs) investigated using chest X-ray (CXR) screening. We identified HHCs …
Massi MN, Hidayah N, Handayani I, Iskandar IW, Djannah F, et al.
…ificance as an immunomarker for several diseases, including tuberculosis. This study aimed to determine the difference between miR-425-5p and miR-4523 expressions in patients with active pulmonary TB (PTB), latent TB infection (LTBI), and lymph node TB (LNTB), whose diagnosis rem…
Yao S, Yan J, Li L, Ma D, Liu J, et al.
Background Multidrug-resistant tuberculosis (MDR-TB) is currently a major problem in China. The prevention and treatment work for MDR-TB patients started late in Anhui province. To determine the prevalence of MDR-TB in sputum smear-positive TB patients (SSPTBPs) and analyze the r…
Utpat KV, Rajpurohit R, Desai U
Background Drug-resistant tuberculosis (DR-TB) is the most exigent and calamitous challenge encountered in treatment of TB. Extra pulmonary (EP) DR-TB poses a complex diagnostic and therapeutic challenge owing to myriad of presentations and paucibacillary nature. Data available o…
Plans-Rubió P, Godoy S, Toledo D, Domínguez A, Caylà J, et al.
…dy was to identify factors associated with non-adherence to tuberculosis (TB) preventive treatment among contacts with latent TB infection for new cases of pulmonary TB cases reported in Catalonia in 2019-2021. All contacts aged 18 years or older with a latent TB infection who re…
Khader Y, Al-Rahamneh MJ, Abu Khudair S, Abaza H, Al Shatnawi A, et al.
Objectives Evaluate and determine the gaps in the National Tuberculosis Program and Tuberculosis Surveillance System in Jordan. Methods A concurrent embedded mixed quantitative/qualitative methods study was conducted to assess the National Tuberculosis Program and Tuberculosis Su…
Bhargava A, Bhargava M, Meher A, Benedetti A, Velayutham B, et al.
Background In India, tuberculosis and undernutrition are syndemics with a high burden of tuberculosis coexisting with a high burden of undernutrition in patients and in the population. The aim of this study was to determine the effect of nutritional supplementation on tuberculosi…
Zifodya JS, Kreniske JS, Schiller I, Kohli M, Dendukuri N, et al.
…on (WHO)-recommended rapid tests that simultaneously detect tuberculosis and rifampicin resistance in people with signs and symptoms of tuberculosis. This review builds on our recent extensive Cochrane Review of Xpert MTB/RIF accuracy. Objectives To compare the diagnostic accurac…
Van Hoving DJ, Griesel R, Meintjes G, Takwoingi Y, Maartens G, et al.
Background Accurate diagnosis of tuberculosis in people living with HIV is difficult. HIV-positive individuals have higher rates of extrapulmonary tuberculosis and the diagnosis of tuberculosis is often limited to imaging results. Ultrasound is such an imaging test that is widely…
Simon C Mendelsohn, Humphrey Mulenga, Michele Tameris, Tumelo Moloantoa, Stephanus T Malherbe, et al.
**BACKGROUND:** More than half of tuberculosis cases detected by community prevalence surveys are classified as asymptomatic. We evaluated yield of symptom and chest radiograph screening of tuberculosis-exposed household contacts in South Africa. **METHODS:** For this prospectiv…
Melike Hazal Can, Sedona Sweeney, Brian W Allwood, Susan E Dorman, Ted Cohen, et al.
**BACKGROUND:** Untreated pulmonary tuberculosis causes ongoing lung damage, which can persist after treatment. Conventional modelling approaches for assessing tuberculosis health effects might not fully capture these mechanisms. We evaluated how tuberculosis-associated lung dama…
Menzies NA, Quaife M, Allwood BW, Byrne AL, Coussens AK, et al.
Background Many individuals who survive tuberculosis disease face ongoing disability and elevated mortality risks. However, the impact of post-tuberculosis sequelae is generally omitted from policy analyses and disease burden estimates. We therefore estimated the global burden of…
Berrocal-Almanza LC, Harris R, Lalor MK, Muzyamba MC, Were J, et al.
… Evaluating interventions that might lead to a reduction in tuberculosis in high-income countries with a low incidence of the disease is key to accelerate progress towards its elimination. In such countries, migrants are known to contribute a large proportion of tuberculosis case…
Ogwang MO, Imbuga M, Ngugi C, Mutharia L, Magoma G, et al.
Introduction Globally anti-tuberculosis drug resistance is one of the major challenges affecting control and prevention of tuberculosis. Kenya is ranked among 30 high burden TB countries globally. However, there is scanty information on second line antituberculosis drug resistanc…
Kim JW, Bowman K, Nazareth J, Lee J, Woltmann G, et al.
Background Incipient tuberculosis, a progressive state of Mycobacterium tuberculosis infection with an increased risk of developing into tuberculosis disease, remains poorly characterised. Animal models suggest an association of progressive infection with bacteraemia. Circulating…
da Costa FBP, Nicol MP, Botha M, Workman L, Arcêncio RA, et al.
Background Paediatric tuberculosis leads to more than 200 000 deaths annually. We aimed to investigate the incidence of Mycobacterium tuberculosis infection and tuberculosis disease in the first decade of life in the Drakenstein Child Health Study (DCHS), a South African cohort i…
Marcy O, Goyet S, Borand L, Msellati P, Ung V, et al.
Background There is no gold standard for tuberculosis diagnosis in children. Clinical Case Definitions for Classification of Intrathoracic Tuberculosis in Children were proposed by international experts in 2012 and updated in 2015. We aimed to compare the 2012 and 2015 Clinical C…
Saunders MJ, Wingfield T, Datta S, Montoya R, Ramos E, et al.
…eness of social protection and biomedical interventions for tuberculosis-affected households might be improved by risk stratification. We therefore derived and externally validated a household-level risk score to predict tuberculosis among contacts of patients with tuberculosis. …
K Monisha, Siddlingappa Hugara, K M Nanditha
**BACKGROUND:** National Tuberculosis Elimination Programme focuses more on open (pulmonary) cases of tuberculosis. In addition to pulmonary tuberculosis, extrapulmonary tuberculosis cases also contribute to the tuberculosis burden and spread of infection among household contacts…