Showing 1–25 of 200 documents
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Km Roma, Suvesh Shrestha, Nirajan Bhandari, Gaurav Jung Shah, Shivam Khetan
Introduction: Pediatric tuberculosis is an infectious disease and is a leading cause of death in Nepal. The incidence of pediatric TB is a key tool of ongoing transmission of tuberculosis within the community and vital indicator of disease control. Its diagnosis is very much chal…
Saïd O. Ali, Hanitriniaina S. C. Samena, Kanto A. Razafindraibe, Annick Robinson
Background: Diagnosing tuberculosis in children remains a challenge especially in low-income countries. The aim of this study was to assess the performance of the scoring system combined to chest x-ray images compared to GeneXpert for diagnosis of pediatric tuberculosis.Methods: …
Daniela Russo
Despite its ancient origins, tuberculosis (TB) remains a major public health problem. In the pediatric population, the prevention and diagnosis of TB is considered a major challenge. For this reason, this scoping review will be conducted in order to systematically map the researc…
Ira Shah, Zahabiya Nalwalla
Pediatric tuberculosis is a proxy indicator for the tuberculosis (TB) burden in the community. Although there has been a decline in the incidence, it is inadequate to meet the global goals for complete eradication of the disease. Childhood TB remains a challenge for clinicians an…
Bineeta Kashyap, Neha Gupta, Pooja Dewan, NP Singh, Ashwani Khanna
Background: Microbiological confirmation of tuberculosis disease in children remains difficult due to paucibacillary disease and inability to obtain optimal samples. Recently introduced Cartridge based nucleic acid amplification test (CBNAAT) has improved microbiological diagnosi…
Meenu Singh, Ragini Bhatia, Madhuri Devaraju, MalkeetSingh Ghuman, Malaisamy Muniyandi, et al.
Background: According to a study on global burden of tuberculosis (TB), India witnessed 60,000 pediatric deaths in the year 2015. In India, most of the children do not get diagnosed with tuberculosis for various reasons. Aims and Objectives: This study will evaluate the cost-effe…
S Firoz, Sonia Bhatt
…tudy was to evaluate the efficacy of PCR targeting IS1081in diagnosis of pediatric tuberculosis and compare the results with MGIT culture.Methods: This prospective study was conducted in the department of pediatrics, S.N. medical college, Agra. 100 subjects (28 pulmonary 72 extra…
Juan J. Gómez-Valverde, Ramon Sanchez, José Luis Ribó, H. Simon Schaaf, Lara García Delgado, et al.
<sec> <title>BACKGROUND</title> Tuberculosis (TB) remains a major cause of morbidity and death worldwide, with a significant impact on children, especially those under the age of 5 years. The complex diagnosis of pediatric TB, compounded by limited access to more accurate diagnos…
Njeru Kenneth Njue, Mburu Samuel, David Nderu
Delayed detection and case diagnosis of pediatric tuberculosis (TB) is a significant factor in TB transmission, morbidity, and mortality especially in resource-limited settings, such as the sub-Saharan Africa, including Kenya.
Christoph Lange, Dumitru Chesov, Olha Konstantynovska, Anna-Maria Mandalakas, Zarir Udwadia
Until the coronavirus disease 2019 pandemic, tuberculosis had been the leading cause of death by an infectious disease worldwide. According to the WHO, there were 1.41 million deaths attributed to tuberculosis in 2019. Globally, the burden of tuberculosis is asymmetrically distri…
Tuberculosis (TB) is an airborne disease that can be spread from person to person.Children that are below 15 years old (also known as Pediatric Tuberculosis) have high probability to develop life threatening disease and the most substantial number of TB cases are observed in chil…
Sobia Rasheed, Salma aziz, Irfan Mehmud, Tanzeela Rani, Nur Ul Ain Umair, et al.
INTRODUCTION: Tuberculosis (TB) is a granulomatous infection caused by Mycobacterium tuberculosis. Pakistan ranks 4th globally. Diagnosis is challenging due to children's inability to expectorate sputum and similar symptoms to other respiratory diseases. Rapid detection is crucia…
Sevliya Öcal Demi̇r, Sabriye Gülçin Bozbeyoğlu, Kardelen Çeliker
Objective: Early diagnosis of tuberculosis (TB) is important in reducing morbidity and mortality. In this study, we aimed to determine the signs and symptoms that provide the differential diagnosis of TB in pediatric patients. Patients and Methods: The study included children dia…
Pooja Shah, Sae Pol, E Prabhakaran, Bhakti Karmalkar, Vaishali Gaikwad, et al.
Abstract Background : Tuberculosis (TB) remains a significant public health challenge in developing countries, including India, where children under 15 years account for 12% of all TB cases. The National Tuberculosis Elimination Programme (NTEP) recommends the use of GeneXpert/Ca…
Bhanu Desai, Rushi N Patel, Yashvi Vijaykumar Dattani, Tamannaben Rameshbhai Ninama, Amay Himanshu Khara, et al.
… TB in children. Paediatric clinical feature is variable in tuberculosis. Many cases of primary TB infection in children are asymptomatic and remain completely unnoticed or accidentally discovered at a later stage. In this study we looked for clinical and radiological presentatio…
Urvashi B. Singh, Manjula Singh, Kiran Bala, Abhinav Srivas, Neeraj Mahajan, et al.
…e, and sensitive diagnostic assays are essential for global tuberculosis (TB) control, especially in high TB burden, resource-limited settings. The current study was designed to evaluate diagnostic accuracy of Truenat MTB-Rif Dx (MolBio) in children less than 18 years of age, wit…
Rina Triasih, Amalia Setyati, Dwikisworo Setyowireni, Titik Nuryastuti, Rachma Dewi Isnaini Putri, et al.
…#x0D; Objective To evaluate the use of Xpert MTB/RIF for TB diagnosis in children.
 Methods We conducted a prospective study in Yogyakarta, Indonesia, involving 19 primary health centers (PHCs) and one provincial hospital. Children aged 0-14 years with suspected TB who visit…
Ery Olivianto, Agustin Iskandar, Triyana Dian Dhuha Akmaly, Sarah Zoraya Mirza, Maxie Felix Jahono
Background: Tuberculosis (TB) remains a major global health challenge, particularly among children. Diagnosing pediatric TB is complicated due to nonspecific symptoms and the difficulty of obtaining sputum samples for microbiological confirmation. Immunological tests, such as the…
Roxana Mansour Ghanaie, Abdollah Karimi, Leila Azimi, Seddon James, Mahshid Nasehi, et al.
… Although the World Health Organization has recommended the diagnosis and prophylactic treatment of latent tuberculous infection (LTBI) in child household contacts of tuberculosis (TB) cases, the national programs in high-burden TB regions rarely implement adequate screening of t…
Amodini Lakshmeswar, Mamta N. Anand, M B Koujalgi
…ackground: In India, an estimated 220,000 children contract tuberculosis (TB) annually, yet the absence of a gold standard test hinders effective diagnosis and reporting of childhood TB. Objective: This study aimed to analyse the clinical profile of childhood tuberculosis, utiliz…
Emel Aytaç Kaplan, Deniz Akan, Nazan Dalgıç, Emel Ekşi, Özge Yapıcı, et al.
Giri: Bu almann amac, ocukluk a akcier tberklozu tansnda spesifik bilgisayarl tomografi (BT) bulgularn tanmlamaktr
Berlian Beatrix Rarome, Nurul Aisah, Retno Asih Setyoningrum, Ni Made Mertaniasih
The diagnosis of childhood tuberculosis remains a challenge worldwide. The GeneXpert MTB/RIF test, a rapid Mycobacteria tuberculosis diagnostic tool, was recommended for use in children. No pediatric studies of GeneXpert MTB/RIF assessing pulmonary tuberculosis within a hospital …
Rika Oktania Sari, Bayu Prabowo
Introduction: Pediatric tuberculosis can cause a variety of problems, including growth failure, disability, and death. In 2021, WHO recorded 10.6 million individuals had tuberculosis globally, with pediatric tuberculosis accounting for 11% of these cases. Indonesia is the second …
Nina T. Castillo-Carandang, Lauren M. Leining, Anna M. Mandalakas, Kristy O. Murray, Jinhua Liao, et al.
…r documents the experiences of rural physicians in managing pediatric tuberculosis (TB) cases before and after disasters in Bohol, Philippines. The participants are from the public and private healthcare systems in municipalities heavily affected and less affected by a 7.2-magnit…
E. S. Ovsyankinа, Л. В. Панова, И. Н. Захарова
Interdisciplinary interaction between phthisiatricians and pediatricians on the issues of detection and diagnosis of tuberculosis provides basis for the reduction of duration of the diagnostic process and the early identification of disease progression. The purpose of this review…