Showing 1–25 of 31 documents
Sorted by hybrid relevance (keyword + semantic via RRF)
Esin Nkereuwem, MBBCh, MSc
…using lung function measurements regardless of symptoms and social determinants for lung health. This study seeks to determine whether, among Gambian children and adolescents aged 19 years and below, PTB is associated with a reduction in pulmonary function measured by spirometry…
Nathalie DE CASTRO, MD PHD
… its care, its impact on quality of life, and the effect of social determinants, situations of precariousness, health literacy, belonging to key populations (incarcerated, migrant and/or homeless people) as well as mental health disorders and addictions on compliance, experience …
Juliet N Sekandi, MD, MS, DrPH
… to determine whether Video Observed Treatment (VDOT) using social internet bundle incentives for tuberculosis (TB) is an effective way to improve medication adherence in TB treatment, compared with standard in-person treatment (home-/ community-based). The study will include tw…
Richard E. Chaisson
…etermine the association of these factors with demographic, social, and clinical characteristics. V. Assess attitudes and beliefs about tuberculosis susceptibility, seriousness, benefits of preventive therapy, barriers to therapy, and self-efficacy as predictors of health-relate…
Mbarara University of Science and Technology
…eal time adherence monitoring linked with SMS reminders and social support notifications can address barriers to sustained ART (antiretroviral therapy) adherence. Such novel interventions addressing TB medication adherence challenges in low resource settings to date are limited. …
Freundeskreis Für Internationale Tuberkulosehilfe e.V
…dy hypothesizes that providing financial and enhanced psychosocial support to people with TB will improve their treatment success and reduce the financial burden on TB-affected households. Background - Previous Studies on Social Protection for TB in Vietnam This study has been …
Mark Hatherill, Limakatso Lebina
The purpose of this study is to evaluate the safety and immunogenicity of MTBVAC in adolescents and adults living with and without HIV in South Africa This study will evaluate the safety and immunogenicity of MTBVAC in adolescents and adults living with and without HIV in South …
King's College London
…g Health Clinic where the investigators will offer a psycho-social intervention for advice and support.
Moustapha Ndir, MD, Christian Lienhardt, MD
…ituation of tuberculosis (TB) in Sénégal 2. to identify the determinants of cure, 3. to develop measures to improve patient's compliance with the treatment that are adapted to the local situation, acceptable, affordable and sustainable 4. to evaluate the impact of these measures …
J. Lucian Davis, MD, MAS, Achilles Katamba, MBChB, DCH, MS, PhD
… tuberculosis (TB) with and without HIV/AIDS and assess the social-behavioral mechanisms underlying the observed treatment effects. Study Design Aim 1. The investigators will conduct a parallel, cluster-randomized, hybrid Type 2, effectiveness-implementation trial at 16 sites i…
Kogieleum Naidoo, MBChB
… HIV-TB services. Understanding the context (environmental, social and political factors) in which we are working is essential to identifying factors that promote or inhibit the implementation of the intervention. We will use the COACH tool (Context Assessment for Community Healt…
Raphael CHIRON, MD
This study evaluates a diagnostic serological test for Non-Tuberculous Mycobacteria (NTM) infection in cystic fibrosis patients by measuring T cell response. It aims to highlight a dynamic response associated to the pathogen's presence. This multicenter case-control study involve…
Igor Rudan
Chronic Respiratory Diseases (CRDs) are common disabling conditions worldwide with high prevalence, morbidity and mortality. More than half of the CRD patients live in low- and middle-income countries (LMICs) where resources for identifying the condition, understanding the diseas…
Degu J Dare, MD, PhD
…dequately adhere to their prescribed regimen due to various social, economic, personal, and healthcare system barriers. However, previous interventions did not adequately consider combined strategies in a way that addressed social, personal, economic, and health system barriers t…
J. Lucian Davis, MD, Achilles Katamba, PhD, Mari Armstrong-Hough, PhD
…implementation trial evaluating a complex, multi-component, social and behavioral intervention designed to normalize the acceptance of HIV testing in the household and increase diagnosis of HIV. An estimated 39 million people worldwide are living with HIV, but nearly half do not…
Bahir Dar University
…hods: self-reported household income loss net of welfare or social assistance payments. This includes the cost that the caregivers bear by contributing their time and in-kind services. Any gain or loss of income reported during each phase or for the entire episode is considered t…
Siyan Yi, PhD, Alvin Teo, MPH
…ed. Limited access to health care, high treatment cost, and social stigma of TB contributed to delayed detection and poor treatment uptake. Other risk factors such as poor living conditions and overcrowding further perpetuated the transmission of TB, which, in turn, leads to soci…
Universidade Federal do Rio de Janeiro
…als in three areas or domains: symptoms, activity and psychosocial aspects. Another instrument used to assess quality of life is the Short-Form 36 (SF-36), a generic questionnaire, self-administered or applied by interview, consisting of 36 items that assess the domains: function…
Maastricht University
…ues, and behavior in educating others who may share similar social backgrounds or life experiences. Prison: A facility that holds convicts who have committed crimes the legal system deems especially serious for more long term sentences. 3.13. Plan for Analysis Collect…
Diane Havlir, MD, Gabriel Chamie, MD, MPH
…d on the PRECEDE framework which outlines the importance of social networks, social influence, and behavior change. The SEARCH-IPT multi-component intervention includes: * A teaching collaborative which will be formed within the randomized clusters of district DHOs and DTLSs to…
JHP Pharmaceuticals LLC
Determine if investigational products and reference standard produce similar responses. Primary: To determine if the 2 investigational products (Aplisol formulated from the new Tuberculin PPD drug substance and the reference standard PPD-S2) produce qualitatively similar respon…
New York State Psychiatric Institute
This hybrid type I effectiveness-implementation trial will increase understanding of the effectiveness and cost-effectiveness of integrating a brief evidence-based treatment for major depressive disorder (MDD) within the tuberculosis (TB) care platform to improve TB and MDD. Find…
Olivier Marcy, Chishala Chabala, Joanna Orne-Gliemann, James Seddon
…luding associated digital tools, and to identify contextual determinants influencing implementation and contribute to improved implementation/adaptations throughout intervention delivery. 3. To assess preferences, acceptability, and perceived feasibility of using the comprehensiv…
J. Lucian Davis, MD
… CHWs and that it will increase self-efficacy and perceived social support among CHWs. Finally, the investigators hypothesize that models evaluating the impact of the user-centered strategy when delivered nationwide will find it cost-effective and able to reduce national TB incid…
Brittney J van de Water, PhD
… into routine management systems, and identify clinic-level determinants of successful SAIA-TB implementation. Recurrent measurement of structural readiness and implementation dose (as a function of quality and quantity) at the clinic level will inform guidance on essential struc…