Showing 176–200 of 200 documents
Sorted by hybrid relevance (keyword + semantic via RRF)
Jens Eckstein, Prof. Dr. med.
…ing ribonucleic acid) in the blood in the context of active tuberculosis is an innovative approach to the detection of new disease-specific biomarkers. The primary goal of this analysis is to define, for the first time, an miRNA fingerprint for tuberculosis in sweat. Samples tha…
Bahir Dar University
… holy water for healing. Therefore, integrating traditional tuberculosis care with modern care increase case detection, decrease diagnosis delay, and avoid catastrophic costs. There is no literature clearly defining integrating traditional TB care with modern care, but for the pu…
Anatoly I Saulin, Master
…bility of the complex therapy of drug-resistant respiratory tuberculosis using the drug Ingaron, a lyophilisate for the preparation of a solution for injection for intramuscular or subcutaneous administration of 500,000 IU. Open prospective observational cohort study. During the…
Ebba Abate, MSc, Ermias Diro, MD, Thomas Schoen, MD PhD
…ent against intestinal helminths in patients with pulmonary tuberculosis undergoing chemotherapy could improve the clinical outcome by enhancing host immunity. Mycobacterium tuberculosis causing tuberculosis (TB) is a major global public health problem. Because of increasing mul…
Per Björkman, M.D., Associate professor, Taye Tolera Balcha, M.D., Erik Sturegård, M.D., Ph.D., Patrik Medstrand, Professor
…adapted methods for management of patients co-infected with tuberculosis (TB) and HIV are needed. Improved detection of TB in patients starting ART, and assessment of co-administration of ART and TB treatment are priorities in this field. Aims: To identify clinical predictors of…
Tongji Hospital
…ifferent treatment options on long-term prognosis of severe tuberculosis patients. All cases of severe tuberculosis diagnosed between 2016 and 2021 were included in the electronic medical record system of one center, and data such as demographics, hospitalization information, cli…
Jeongha Mok, MD, PhD
…ion system (targeted bronchial washing) for detection of M. tuberculosis and resistant-conferring mutations in patients with pulmonary tuberculosis. Time to appropriate treatment and stain/culture conversion are also evaluated. Comparisons of detection rate of M. tuberculosis an…
GSK Clinical Trials
Vaccination against tuberculosis (TB) /healthy PPD-negative adults aged 18 to 45 years.Three doses of primary vaccination followed by a booster dose after completion of primary vaccination course. Booster vaccination will be given only to subjects receiving the candidate tubercul…
Monde Muyoyeta, MD, PhD
Tuberculosis and HIV continue to be major public health problems in resource constrained settings like Zambia. Zambia is among the top 30 highest burden countries globally. The major drivers of TB in the Africa region is the HIV epidemic. Inadequate TB diagnostic tools with failu…
Beijing Chest Hospital
…inical trial is to investigate the correlation between anti-tuberculosis drug concentration monitoring and treatment efficacy and safety through analytical studies.The main questions it aims to answer include: Guidance for individualized dosage adjustment of anti-tuberculosis dr…
amani omar, professor
…etect the characteristics, pattern and outcome of pulmonary tuberculosis patients treated at Assiut University Hospital by collecting their demographic, clinical, laboratory and radiological data. Tuberculosis (TB) is a problem of global importance, it is a medical, social and e…
Adithya Cattamanchi
…B worldwide. The Assessing Diagnostics At Point-of-care for Tuberculosis (ADAPT) study seeks to reduce the burden of TB worldwide by evaluating faster, simpler, and less expensive TB triage and diagnostic tests. The Assessing Diagnostics At Point-of-care for Tuberculosis (ADAPT)…
Nathalie DE CASTRO, MD, Celso KHOSA, MD
…and safety of adding adalimumab to standard treatment (anti-tuberculosis drugs and corticosteroids) in HIV patients with tuberculosis meningitis in 3 countries (Brazil, Mozambique, and Zambia). Phase II multicenter, open-label, randomized, proof of concept, comparative trial wit…
Antonio Lombardi, MD
…ial combination regimen(s) to treat patients with pulmonary tuberculosis (TB). The primary purpose of the Male Reproductive Safety - "BPaMZ/SEM"- clinical study is to evaluate the potential effect of pretomanid on human testicular function whilst being used in a 26 weeks antimicr…
Michael B Krawinkel, Prof. Dr.
Tuberculosis (TB) patients often have a lower body mass index (BMI) and experience wasting. Wasting reduces lean body mass and may cause physical function impairment. This study aimed to determine the efficacy of fermented soybeans (tempeh) as a food supplement on body weight and…
Sang Min Lee, MD, PhD
…ients who present with hemoptysis, and those with pulmonary tuberculosis, non-tuberculous mycobacterial pulmonary disease (NTM-PD), and lung cancer, analyzing respiratory specimen acquired by bronchoscopic approach. Subjects who were going to undergo bronchoscopy for hemoptysis …
Noha S Shafik, Lecturer, Asmaa T Mostafa, Lecturer, Ebtisam M Gad, Lecturer, Mona M Abdelrahman, Lecturer, Dina H Mohamed, Lecturer
Tuberculosis (TB) is caused by Mycobacterium tuberculosis and is one of the top 10 causes of mortality worldwide. It is estimated that in 2017, 10 million people were infected with TB, and 1.6 million died from the disease, including 0.3 million people with human immunodeficiency…
Elinore F McCance-Katz, M.D., Ph.D.
…s needed to be completed at UCSF/SFGH will be discussed) or tuberculosis(TB) (rifampin or rifabutin) medications (note: supplement application currently pending). Participants are those with opioid dependence who qualify for buprenorphine/naloxone treatment or they are healthy su…
Norbert Heinrich, Christina Manyama, Simon E Koele, Stellah Mpagama, Francis Mhimbira, et al.
…component globally in first-line therapy for drug-resistant tuberculosis but has considerable toxicity. New and safer alternative oxazolidinones are needed. Sutezolid is one such promising alternative. We aimed to evaluate preliminary efficacy and safety of sutezolid and to ident…
Guang Ji
…ving Standard Combination Therapy for Retreatment Pulmonary Tuberculosis. Retreatment of tuberculosis involves the management of entities as diverse as relapse, failure, treatment after default, and poor patient adherence to the previous treatment. The emergence of conditions fo…
Adrian Martineau, Prof
…rmine whether vitamin D3 has potential to prevent recurrent tuberculosis (TB), as indicated by enhanced resolution of pulmonary inflammation detected using 18F-FDG PET-CT scanning. The extent of pulmonary inflammation detectable on PET-CT scanning is a validated biomarker that ha…
Richard Chaisson, MD
…based screening program in local, decentralized clinics for tuberculosis (TB) screening of child contacts less than 5 years old who were exposed to tuberculosis in the home. This will allow nurses in decentralized clinics to either start IPT for those asymptomatic patients and re…
LINA LEE, MD,PhD
…o determine whether the monoclonal protein in patients with tuberculosis and monoclonal gammopathy has anti-tuberculous activity, and whether genes coding their monoclonal proteins show characteristic mutations. Monoclonal immunoglobulins arise from abnormal proliferation of a s…
Giovan Battista Migliori, Prof
Pulmonary tuberculosis (TB) is an important risk factor for chronic respiratory disease due to residual lung damage. A recent review of the literature on TB sequelae and rehabilitation has provided clear evidence that TB is definitively responsible for lung function impairment. F…
Centers for Disease Control and Prevention
…ts who began study phase therapy with signs and symptoms of tuberculosis or cultures positive for M. tuberculosis. To compare the toxicity associated with the two study regimens by comparing discontinuation rates due to adverse events and occurrence rates of signs and symptoms a…