Showing 26–50 of 200 documents
Sorted by hybrid relevance (keyword + semantic via RRF)
Mary Jane Rotheram-Borus, Ph.D.
…his study is to test a mother-to-mother intervention during pregnancy and after delivery with Mothers Living with HIV (MLH)in South Africa. We hypothesize that the intervention will enhance the adjustment of the children of MLH by improving the health and mental health of MLH whi…
Amita Gupta, MD, MHS
…in low-income settings. When TB occurs during or soon after pregnancy, it can cause complications for the mother as well as infant TB or death. Infant TB is very difficult to diagnose, and up to half of infant TB cases are caused by maternal TB. It has been shown that treatment f…
Lu Shuihua, Bachelor
…, electrocardiogram, chest CT, HIV antibody test, and blood pregnancy examination of women of childbearing age; Vital signs examination before the skin test, The injection site was photographed 0min after the skin test, Vital signs were performed 30min after the skin test; Vital …
Christina Yoon, MD
…vels) and the optimal timing of TPT initiation, relative to pregnancy (immediately during pregnancy or deferred to postpartum). Because undiagnosed TB among pregnant women with HIV is associated with many devastating complications to both the mother and fetus, this research has t…
University of Liverpool
… example during periods of rapid childhood growth or during pregnancy and transition back to non-pregnant physiological state. It is aimed to obtain 20 sparse PK profiles in each of the following groups (pregnant, child \<5, child 6-11, adolescent 12-18, obese (BMI \>30 Kg/m2), …
Ian Toma, MD, PhD
…agnosis with HIV (first OBGYN consultation @ 12-16 weeks of pregnancy - TP1); repeated HIV test in 3rd trimester of pregnancy (34-36 weeks- TP2); umbilical cord blood (after delivery and ligation- TP3); neonates (24 hours after birth and after HBV vaccination, prior to BCG vaccin…
Maryline Bonnet, MD, Nilesh Bhatt, MD
…-income countries, poor access to EFV, contradiction during pregnancy and absence of FDC containing EFV lead to difficulties in HIV-TB treatment. Despite 2 limited retrospective studies and a non-randomised prospective study, which report good virological response at 6 months in…
Giuseppe Pantaleo, MD
…2 dose regimen, 1 due to withdrawal of consent and 1 due to pregnancy \[the subject delivered a healthy boy without complications and was followed to study completion\]; and 1 in the AERAS-404 3 dose regimen, due to inability to discontinue daily isotretinoin started after the se…
Joseph A Kovacs, M.D.
…ital signs taken and give a blood sample. Women will have a pregnancy test. Participants cannot take any other medicines during the study, including vitamins. Only occasional, infrequent use of acetaminophen (Tylenol , max 2000 mg/day), ibuprofen (Motrin or Advil ), naproxen (Al…
National Institute of Allergy and Infectious Diseases (NIAID)
…oing a physical exam and blood collection, and undergoing a pregnancy test for women of reproductive potential. Participants also will be required to keep a diary of the times they took outpatient study drugs, any medications taken other than the study drug, and any symptoms expe…
Kelly Dooley, MD
…ye exam, an electrocardiogram (ECG) to measure heartbeat, a pregnancy test, and a blood test. Certain behaviors and substances will be prohibited during the study, including consuming grapefruit, alcohol, or caffeine (on PK visit days); taking nutritional supplements, over-the-co…
Shuang Wei, M.D.
…men of childbearing age, not pregnant, willing to undergo a pregnancy test with a negative result, and willing to use highly effective contraceptive measures from signing the informed consent until 3 months after the end of the study treatment. For men of childbearing age, using…
Kelly Dooley, MD, PhD, Gary Maartens, MBChB, MMed
…um sample collection, hair sample collection, chest x-rays, pregnancy testing, electrocardiograms (ECGs), and adherence questionnaires. Participants were also asked to take part in an optional cerebrospinal fluid sampling study that entailed a lumbar puncture, to be done at week…
friedrich Thienemann, MD
…ng. Sputum will be collected and screening for diabetes and pregnancy will be completed. Whole-body PET/CTs will be performed at 0 months, 6 months, and 12 months. Spinal biopsies will be gathered if surgery is being performed. Samples of the sites of disease will be acquired if …
François Nosten, Professor
…me countries. However, there has been no sufficient data on pregnancy and people with co-morbidity especially HIV/TB patients. As there is limited knowledge about immunogenicity of COVID-19 vaccines among TB patients, examination of immunological responses from the COVID-19 vacc…
James Kublin, MD, MPH
…uations, blood draws, urine collections, skin biopsies, and pregnancy tests. This study will measure the rate of replication by utilizing qPCR and in vitro culture, systemic innate and adaptive immune responses, including humoral and cellular assay analyses and the evaluation and…
Ben Morton, MD. MPH, MBChB
…lateral flow test (if required by UKHSA) and storage, urine pregnancy test (females only). The following blood tests will be taken: HIV test, hepatitis serology, full blood count and clotting, stored serum, blood PBMCs. BCG intradermal injection (day 0): For both parts of the s…
Constance A Benson, MD, Umesh Lalloo, MD, FRCP
… CD4 cell count, HIV viral load, hematology, chemistry, and pregnancy testing in women of reproductive potential. Sputum, serum, and urine were stored for use in future analyses. An intensive PK visit occurred at day 12. PK blood draws in participants in Arms A and C were at RBT …
Hongfei Duan, MD
… limit of the normal range; if they were known or suspected pregnancy; if they were known or suspected isoniazid and/or rifampin resistant; if they were lack of consent； if they were any participant for whom investigators judge this study is not appropriated. Participants will b…
Yi Mo, Master
…e) from the first dose to 6 months after the full dose. All pregnancy events from the first dose to 30 days after the full dose were collected. In the control group, only all AESI (including immune system related diseases such as thyroid/parathyroid diseases) were collected u…
BONNET Maryline, MD
…/biluribin \<5xULN; no grade 4 clinical/biological sign; no pregnancy + barrier contraception; agree to participate and sign a consent form. Randomisation block, 1:1:1. Sample size: 28 patients to show that the reduction of AUC of EFV with R20mg/Kg vs no R is not greater to 30%,…
Estee Torok
…a: positive CSF Gram or India ink stain, known or suspected pregnancy; antituberculous treatment 8 to 30 days immediately prior to recruitment; previous antiretroviral therapy; laboratory contraindications to antiretroviral or antituberculous therapy; lack of consent. Consent: W…
Graeme Meintjes, MD MPH PhD
…nt for trial. Exclusion criteria include: Kaposi's sarcoma, pregnancy, TB meningitis or tuberculoma at TB diagnosis (because these patients receive corticosteroids), known rifampicin-resistant TB, being on corticosteroids for another indication within the past 7 days, on other im…
Olanisun O Adewole, MD, Olanisun O Adewole, MD, Bolanle A Omotoso, MD
…opometry documented, will be screened for HIV, Diabetes and Pregnancy (in females), and have sputum collected for mycobacterial smear and culture. At baseline visit (visit at which study drug is initiated), sputum will be collected for mycobacterial smear and culture, blood samp…
Scott K Heysell, Stellah G Mpagama, Edwin Nuwagira, Bibie Said, Mark Conaway, et al.
…ntituberculosis therapy within 6 months of hospitalisation, pregnancy or lactation, allergies to antituberculosis therapy, another investigational drug within the past month, chronic liver disease, heavy alcohol use, positive serum cryptococcal antigen, or anticipated significant…