Showing 1–25 of 25 documents
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Khuat Thi Hai Oanh, Nguyen Thuy Linh, Masami Fujita, Lam Ngoc Thuy, Nguyen Hong Phuc, et al.
Tuberculosis is reported as highly prevalent among slum dwellers and unhoused individuals worldwide. We conducted a study to estimate the prevalence of tuberculosis among slum dwellers and unhoused individuals in Ho Chi Minh City, Vietnam, and identified risk factors. An intervie…
Kada Bentata, Sofiane Alihalassa, Merzak Gharnaout, Mohamed Abdellatif Bennani, Yahia Berrabah
Tuberculosis continues to pose a major challenge to the healthcare systems of many countries, particularly those with low to moderate incomes. Since gaining independence in 1962, Algeria has made significant economic and healthcare development strides. Tuberculosis control remain…
Juan Gabriel Sánchez-Cano, Laura Muñoz-Echeverría, María Casco-García, Leonor Moreno-Núñez
HIV-tuberculosis coinfection remains a major global health challenge and the concomitant use of antiretroviral therapy with rifampicin-based tuberculosis treatment is frequently complicated by clinically relevant drug-drug interactions. Rifampicin strongly induces CYP3A4 and UGT1…
Bhaskar Mitra, Ranjan Kr Das, V K Arora
Tuberculosis (TB) remains one of humanity's oldest and deadliest infectious diseases, yet its history is not written solely in medical texts and epidemiological tables. An extraordinary parallel narrative exists in philately-through tuberculosis seals and Christmas seals-those do…
LiSheng Qi, QinWen Gu, Bo Chen, DuJiang Yang, DongDong Li
…l paradigm in which exosomal miR-125b-5p from Mycobacterium tuberculosis-infected macrophages impairs osteoblast function by targeting IGF2, thereby linking pulmonary infection to systemic osteoporosis. While this work provides a valuable mechanistic insight, our letter offers a …
Nawang Yanga
Tuberculosis (TB) disproportionately affects immigrants and refugees in Canada, who accounted for 80% of active TB cases in 2023 despite making up only 23% of the population. This commentary highlights the urgent need to address systemic barriers that hinder access to timely and …
Shree V Dhotre, Pradnya S Dhotre, Ajay M Gavkare, Basavraj S Nagoba
… describing mixed connective tissue disease coexisting with tuberculosis (TB) provides an important contribution to the growing literature on complex autoimmune-infectious disease interactions. This letter expands on the diagnostic challenges highlighted by the authors by definin…
Ram W Sabnis
…ns, use of such compounds in treating bacterial infections, tuberculosis or leprosy, and processes for preparing such compounds.
Rogelio Hernández Pando
Tuberculosis (TB) remains a global health challenge, partly due to difficulties in diagnosis and the prolonged duration and toxicity of standard antibiotic regimens [...].
Fumu Wang, Haiming Wang
The coexistence of tuberculosis (TB) and diabetes mellitus (DM) presents a significant global health challenge, particularly in patients with poorly controlled glycemic levels. Subclinical or silent pulmonary TB in diabetic individuals-characterized by the absence of classic symp…
Vasiliki Kolokotroni, Irini Gerogianni, Konstantinos I Gourgoulianis, Garyfallia Perlepe
**BACKGROUND:** Monitoring treatment response in pulmonary tuberculosis (TB) is critical, but non-invasive biomarkers are limited for patients unable to produce sputum. **OBJECTIVE:** To evaluate the utility of the PATHFAST TB LAM Ag assay in urine for diagnosis and treatment mo…
Wenping Gong, Ashok Aspatwar
Tuberculosis is a chronic infectious disease caused by(MTB) and remains a major global public health challenge [...].
Saima Aleem, Saara Khan, Zohaib Khan, Zeeshan Kibria, Saima Sheikh, et al.
With the health and social care research trends shifting towards conception, development, delivery, and implementation of more evidence-based interventions, public partnerships have emerged as key foundational moral components to tailor best practices to conduct research with the…
Tomomi Tezuka, Naomi Ito, Kenzo Takahashi
…l health programs, including those addressing malaria, HIV, tuberculosis, and polio, and has caused funding shortages for non-profit and international organizations like GAVI and the World Bank. Projections indicate dire consequences. According to USAID, a potential 18 million ad…
Suryasnata Bhowmik, Adrija Hajra, Dhrubajyoti Bandyopadhyay
…ation strategies. The ongoing battle against drug-resistant tuberculosis (TB) illustrates the complexity of genomic variants in predicting resistance, highlighting the need for integrated diagnostic tools. Additionally, genome-wide association studies reveal antibiotic resistance…
D Pedrazzoli, F Khalid, F Mavhunga, T Kasaeva, S B Syed, et al.
…sustainable outcomes. Drawing on WHO's recent policy brief 'Tuberculosis and primary health care: synergies and opportunities towards universal health coverage', this article highlights the importance of reorienting health systems towards PHC to strengthen TB responses through in…
Santosha Kelamane, Ghada Muhjazi, Nevin Wilson, Martin van den Boom
Tuberculosis (TB) remains a public health threat in low- and middle-income countries (LMICs) of the World Health Organization (WHO) Eastern Mediterranean Region (EMR), driven by a combination of social determinants including undernutrition, fragile health systems, conflict-relate…
Martyna Biała, Brygida Knysz
…ttings due to the widespread use of antiretroviral therapy, tuberculosis remains a serious threat and a major cause of morbidity and mortality among HIV-infected individuals worldwide. Early diagnosis of HIV infection, timely initiation of antiretroviral therapy with good adheren…
Farzana Sathar, Claire du Toit, Violet Chihota, Conor Eastop, Norbert Ndjeka, et al.
Mycobacterium tuberculosis (TB) antigen-based skin tests, known as TB-specific skin tests (TBSTs), have been recommended by the World Health Organization (WHO) to test for TB infection (TBI). In light of these new recommendations, we conducted a situational analysis and market as…
Taiwo Oluwaseun Sokunbi, Abbas Bashir Umar, Uko Bassey Eyo
…th programs addressing HIV/AIDS, maternal and child health, tuberculosis, and malaria, which heavily rely on external funding. Reduced funding will disproportionately affect low- and middle-income African countries, increasing the financial burden on households and limiting acces…
Idris Zubairu Sadiq
…influences, and poverty. Common infectious diseases such as tuberculosis, malaria, HIV/AIDS, cholera, and dengue fever are significantly influenced by poor sanitation, inadequate housing, climate change, and gender disparities. Key interventions, including enhancing access to cle…
Santosh Sah, Areeba Ahsan, Tularam Yadav
Drug-resistant tuberculosis (DR-TB) is a serious public health threat, and Pakistan is one of the most impacted nations. The long treatment duration of traditional regimens puts a great burden on healthcare systems, especially in resource-constrained environments. Accordingly, th…
Kai-Yan Liu, Xiao-Bing Li
… increase in response to inflammatory conditions, including tuberculosis and malignancies. Elevated ADA levels in pleural have been shown to correlate with inflammatory exudates, making it a valuable biomarker for differentiating between inflammatory and non-inflammatory effusion…
Arshad Rizvi, Yash Gupta
Mycobacterial diseases, particularly tuberculosis (TB), continue to impose a substantial global health burden, disproportionately affecting populations in low- and middle-income countries [...].
Sheetal Gandotra, Yogendra Singh
The bacterium that causes TB can hide in liver cells called hepatocytes, and reprogram their metabolism for its own benefit.