Showing 1–25 of 33 documents
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Carlos Brito, Rita Moraes de Brito
…he article "Brazilian Recommendations for the Management of Tuberculosis Infection in Immune-Mediated Inflammatory Diseases" by Viviane de Souza et al. presents important discussions on the subject; however, the recommendation for annual repetition of the TST/IGRA test for three …
Viviane Angelina de Souza, Ana Luiza Mendes Amorim Caparroz, Virginia Fernandes Moça Trevisani, Anna Carolina Faria Moreira Gomes Tavares, Ana Karla Guedes de Melo, et al.
…esponse to a letter addressing the Brazilian guidelines for tuberculosis infection (TBI) screening in immune-mediated inflammatory diseases (IMID), we clarify that the recommendations reflect a structured, evidence-based consensus developed by a multidisciplinary panel, in accord…
Muhamad Khizar, Ehsanullah Alokozay, Muhammad Junaid, Najibullah Alokozay
We commend Oh et al.'s recent analysis of TB preventive treatment (TPT) in the Western Pacific Region, but note important gaps and ways forward. We first caution that reliance on routine program data may overestimate gains. For example, China's passive surveillance misses ≈…
Khuat Thi Hai Oanh, Nguyen Thuy Linh, Masami Fujita, Lam Ngoc Thuy, Nguyen Hong Phuc, et al.
Tuberculosis is reported as highly prevalent among slum dwellers and unhoused individuals worldwide. We conducted a study to estimate the prevalence of tuberculosis among slum dwellers and unhoused individuals in Ho Chi Minh City, Vietnam, and identified risk factors. An intervie…
Kada Bentata, Sofiane Alihalassa, Merzak Gharnaout, Mohamed Abdellatif Bennani, Yahia Berrabah
Tuberculosis continues to pose a major challenge to the healthcare systems of many countries, particularly those with low to moderate incomes. Since gaining independence in 1962, Algeria has made significant economic and healthcare development strides. Tuberculosis control remain…
Juan Gabriel Sánchez-Cano, Laura Muñoz-Echeverría, María Casco-García, Leonor Moreno-Núñez
HIV-tuberculosis coinfection remains a major global health challenge and the concomitant use of antiretroviral therapy with rifampicin-based tuberculosis treatment is frequently complicated by clinically relevant drug-drug interactions. Rifampicin strongly induces CYP3A4 and UGT1…
Dr Garima Rawat, Dr Aditi Shukla, Dr Hema Malini Aiyer
Laryngeal tuberculosis (TB) is a rare form of extrapulmonary tuberculosis and its isolated presentation without concurrent pulmonary involvement is even rare [1, 2] This poses significant diagnostic challenges as it can present with nonspecific symptoms such as hoarseness, throat…
Balsam Barkous, Saba Boubakri, Helmi Ben Saad
… ventilatory patterns, with the clinical characteristics of tuberculosis-destroyed lung patients. This study is significant for healthcare providers managing long-term tuberculosis cases, especially with the rise of multidrug-resistant strains. By analyzing spirometry data, the s…
Bhaskar Mitra, Ranjan Kr Das, V K Arora
Tuberculosis (TB) remains one of humanity's oldest and deadliest infectious diseases, yet its history is not written solely in medical texts and epidemiological tables. An extraordinary parallel narrative exists in philately-through tuberculosis seals and Christmas seals-those do…
LiSheng Qi, QinWen Gu, Bo Chen, DuJiang Yang, DongDong Li
…l paradigm in which exosomal miR-125b-5p from Mycobacterium tuberculosis-infected macrophages impairs osteoblast function by targeting IGF2, thereby linking pulmonary infection to systemic osteoporosis. While this work provides a valuable mechanistic insight, our letter offers a …
Nawang Yanga
Tuberculosis (TB) disproportionately affects immigrants and refugees in Canada, who accounted for 80% of active TB cases in 2023 despite making up only 23% of the population. This commentary highlights the urgent need to address systemic barriers that hinder access to timely and …
Wenping Gong, Ashok Aspatwar
Tuberculosis is a chronic infectious disease caused by(MTB) and remains a major global public health challenge [...].
Vasiliki Kolokotroni, Irini Gerogianni, Konstantinos I Gourgoulianis, Garyfallia Perlepe
**BACKGROUND:** Monitoring treatment response in pulmonary tuberculosis (TB) is critical, but non-invasive biomarkers are limited for patients unable to produce sputum. **OBJECTIVE:** To evaluate the utility of the PATHFAST TB LAM Ag assay in urine for diagnosis and treatment mo…
Shree V Dhotre, Pradnya S Dhotre, Ajay M Gavkare, Basavraj S Nagoba
… describing mixed connective tissue disease coexisting with tuberculosis (TB) provides an important contribution to the growing literature on complex autoimmune-infectious disease interactions. This letter expands on the diagnostic challenges highlighted by the authors by definin…
Rogelio Hernández Pando
Tuberculosis (TB) remains a global health challenge, partly due to difficulties in diagnosis and the prolonged duration and toxicity of standard antibiotic regimens [...].
Ram W Sabnis
…ns, use of such compounds in treating bacterial infections, tuberculosis or leprosy, and processes for preparing such compounds.
Fumu Wang, Haiming Wang
The coexistence of tuberculosis (TB) and diabetes mellitus (DM) presents a significant global health challenge, particularly in patients with poorly controlled glycemic levels. Subclinical or silent pulmonary TB in diabetic individuals-characterized by the absence of classic symp…
Saima Aleem, Saara Khan, Zohaib Khan, Zeeshan Kibria, Saima Sheikh, et al.
With the health and social care research trends shifting towards conception, development, delivery, and implementation of more evidence-based interventions, public partnerships have emerged as key foundational moral components to tailor best practices to conduct research with the…
Parth Aphale, Shashank Dokania, Himanshu Shekhar
…y Song et al. [1] detailing the significant improvements in Tuberculosis Infection Control (TBIC) implementation rates across designated hospitals in Jiangsu Province, China, provides valuable data on the feasibility of programmatic interventions in high-burden settings. The demo…
Tomomi Tezuka, Naomi Ito, Kenzo Takahashi
…l health programs, including those addressing malaria, HIV, tuberculosis, and polio, and has caused funding shortages for non-profit and international organizations like GAVI and the World Bank. Projections indicate dire consequences. According to USAID, a potential 18 million ad…
Idris Zubairu Sadiq
…influences, and poverty. Common infectious diseases such as tuberculosis, malaria, HIV/AIDS, cholera, and dengue fever are significantly influenced by poor sanitation, inadequate housing, climate change, and gender disparities. Key interventions, including enhancing access to cle…
Santosha Kelamane, Ghada Muhjazi, Nevin Wilson, Martin van den Boom
Tuberculosis (TB) remains a public health threat in low- and middle-income countries (LMICs) of the World Health Organization (WHO) Eastern Mediterranean Region (EMR), driven by a combination of social determinants including undernutrition, fragile health systems, conflict-relate…
D Pedrazzoli, F Khalid, F Mavhunga, T Kasaeva, S B Syed, et al.
…sustainable outcomes. Drawing on WHO's recent policy brief 'Tuberculosis and primary health care: synergies and opportunities towards universal health coverage', this article highlights the importance of reorienting health systems towards PHC to strengthen TB responses through in…
Eric T Roberts, Matthew Murrill, Gabriela Schmajuk, Jinoos Yazdany
We argue for universal latent tuberculosis infection (LTBI) screening prior to administration of biologic or targeted synthetic DMARDs (b/tsDMARDs). First, though evidence about the risk of LTBI reactivation for newer b/tsDMARDs is accumulating these studies are conducted in popu…
Santosh Sah, Areeba Ahsan, Tularam Yadav
Drug-resistant tuberculosis (DR-TB) is a serious public health threat, and Pakistan is one of the most impacted nations. The long treatment duration of traditional regimens puts a great burden on healthcare systems, especially in resource-constrained environments. Accordingly, th…